Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 4. P. 18-24

RADIATION MEDICINE

V.A. Osipov, A.M. Lyaginskaya, I.M. Petoyan, A.P. Ermalitskiy, N.M. Karelina

Innate Development Defects in Children of Smolensk NPP Personnel and their Connection with the Occupational Exposure to the Fathers

Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To study the common frequency of innate development defects (IDD) in the newborn children in the families of man-personnel of the basic shops of Smolensk NPP and to find out their connection with the occupational exposure to fathers.

Material and methods: As the material of study the data of medical individual stories «The history of the development of kind» and «The history of the development of newborn» in Desnogorsk during 1989–2012 were examined. By the method of continuous sample were registered 1245 cases of child-bearing by living child in the families of man-personnel of the basic shops of Smolensk NPP and by the method of the random sampling – 1294 cases of child-bearing in the families of men from the population of Desnogorsk (control group).

Results: The generation of children with the innate defects both in the families of man-personnel Smolensk NPP and in the control group, during the 20-year observation 1989–2010 is characterized by two periods, which are statistically distinguished by the frequency of IDD: 1989–1998 and 2001–2010. Frequency of the birth of children with IDD in 1989–1998 was reliably higher, in comparison with 2001–2010. Summation frequency of the generation of children with the innate defects and with small anomalies of development in the families of man-personnel Smolensk NPP in 1989–1998 was statistically reliably higher, than in the families of the men of control group, and in 2001–2010 the frequency of this index in the groups of observation statically did not differ.

Conclusion: Frequency of IDD, which exceeds reference quantities by the group of the children of personnel is, apparently, caused by of many unfavorable factors, such as the maternal and paternal factors of risk. In the general structure of IDD in the children of the group of personnel, as in the children of control group, portion of IDD with the high mutation hereditary component composed 30 % and 39 % respectively, and the portion of IDD of multifactor nature – 70 % and 61 % respectively. The exceeding frequency of IDD in the children of the group of personnel is caused by the portion of IDD of multifactor genesis.

Key words: innate development defects in the children, Smolensk NPP, occupational exposure of the man-personnel