Medical Radiology and Radiation Safety. 2013. Vol. 58. No. 6. P. 36-43
NUCLEAR MEDICINE
Yu.A. Kurachenko1, N.K. Voznesensky1, Eu.S. Matusevich1, L.A. Lebedev2, V.A. Levchenko3, A.V. Levchenko3
Deep-Seated Neoplasm Neutron-Capture Therapy at the Modified Beam of the MARS Medical Reactor
1. Institute of Nuclear Power Engineering in National Research Nuclear University «MEPhI», Obninsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Rosatom Nuclear Energy State Corporation, Moscow, Russia; 3. Simulation Systems Ltd, Obninsk, Russia
Abstract
The MARS medical reactor beam is analyzed for neutron capture therapy of deep neoplasm. Necessary conditions of the new approach are based on: a) precise delivery of the pharmaceutical with Boron or Gadolinium to a target and long-time confinement it, and b) using a high-energy & high fluence rate neutron beam, which provides neutron deep penetration. Results of the numerical experiment for administered dose delivery to a deep seated target for the modified MARS reactor beam are presented. It is shown, that new quality of results is quite achievable in acceptable time of an exposure.
Key words: NCT new concept, precise B/Gd delivery, high-energy neutron beam, removal block optimization, Gd-capture therapy, MARS reactor beam modification