Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 6. P. 5-8

RADIATION BIOLOGY

V.F. Stepanenko, I.G. Belukha, D.V. Dubov, E.K. Yaskova, A.F. Tsyb

Nanodosymetric Basing of Selective Irradiation to Chromosomes with Cascade Irradiatora of Low-Energy Electrons

Medical Radiological Research Center, Obninsk, Kaluga region, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Nanodosimertry data as a ground for the possibility of selective irradiation on chromosomes by cascade emitters of low energy Auger electrons and photoelectrons, generated by the photoelectric effect on the native and on the incorporated atoms in the DNA resulted from external irradiation by low-energy photons, are presented. A theoretical evaluation of the biological effectiveness of photon activation effect on cultured B-16 melanoma cells with included to the DNA molecule of stable bromine or iodine atoms was performed.

Key words: nanodosimetry, chromosomes, cascade irradiators of electrons

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