Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 6. P. 68-73

NUCLEAR MEDICINE

T.N. Sharypova, S.L. Timerbaeva

Features of SPECT Visualization of Brain for Functional Changes Estimation in the Focal Distention Patients

Research Center of Neurology of RAMS, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose:To estimate features and specific SPECT visualizations into Brodmann`s Maps in patients with cervical distention (CD).

Material and method: 16 patients with CD and 7 controls studied with SPECT (e.cam Siemens) after intravenous injection with 700 MBk 99mTc-teoxim (analog HMPAO). For analysis of results the program “Neurogam” with standardized perfusion middle maps was used.

Results: Different variants of the image cerebral perfusion by criterions hyper- or hypo-perfusion into Brodmann’s Maps have been obtained: in the group CD - increase cerebral perfusion into 1-3, 4, 6 and 40 at 81 % into right brain and 75 % into left brain; the control group - normal perfusion into 1-3, 4, 6, 5, 7, 39, 40 (U-criterion of Mann-Whitney p < 0. 001).

Conclusions: Maps of brain perfusion reflect microcirculation and functional deviations in Brodmann`s Maps 1-3, 4, 6, 5, 7, 39, 40 of CD patients in comparison with the control group.

Key words: SPECT, brain, focal dystonia, brodmann’s maps