Саенко Владимир Александрович

доктор биологических наук (Dr. Sc. Biol), профессор медицинской школы Университета Нагасаки, кафедра радиационной эпидемиологии. Нагасаки, Япония (Department of Radiation Molecular Epidemiology, Atomic Bomb Disease Institute Nagasaki University Nagasaki Japan)

 ПУБЛИКАЦИИ 2013–2017 гг.

Отрасль: 03.00.00 Биологические науки. Группы специальностей: 03.01.00 Физико-химическая биология (03.01.01 Радиобиология); 03.02.00 Общая биология (03.02.08 Экология)

Отрасль: 05.00.00 Технические науки. Группа специальностей: 05.26.00 Безопасность деятельности человека (05.26.05. Ядерная и радиационная безопасность)

Отрасль: 14.00.00 Медицинские науким. Группа специальностей: 14.02.00 Профилактическая медицина (14.02.02 Эпидемиология)

  1. Bogdanova TI, SaenkoVA, Hirokawa M, Ito M, Zurnadzhy LY, Hayashi T, Rogounovitch TI, Miyauchi A, Tronko MD, Yamashita Comparative histopathological analysis of sporadic pediatric papillary thyroid carcinoma from Japan and Ukraine. Endocr J 2017;64(10):977-993. DOI: 10.1507/endocrj.EJ17-0134.
  2. Khvostunov IK, SaenkoVA, Krylov V, Rodichev A, Yamashita Cytogenetic biodosimetry and dose-rate effect after radioiodine therapy for thyroid cancer. Radiat Environ Biophys 2017;56(3):213-226. DOI: 10.1007/s00411-017-0696-3.
  3. Iyama K, Matsuse M, Mitsutake N, Rogounovitch T, Saenko VA, Suzuki K, Ashizawa M, Ookouchi C, Suzuki S, Mizunuma H, Fukushima T, Suzuki S, Yamashita S. Identification of Three Novel Fusion Oncogenes, SQSTM1/NTRK3, AFAP1L2/RET, and PPFIBP2/RET in Thyroid Cancers of Young Patients in Fukushima. Thyroid 2017, 27(6):811-818. DOI: 10.1089/thy.2016.0673.
  4. Bilous N, Abramenko I, Saenko V, Chumak A, Dyagil I, Martina Z, Kryachok I. Clinical relevance of TP53 polymorphic genetic variations in chronic lymphocytic leukemia. Leuk Res 2017;58:1-8. DOI: 10.1016/j.leukres.2017.03.009.
  5. Yamashita S, Saenko VA. What is the "Screening Effect" Six years after the Fukushima Nuclear Power Plant Accident? Thyroid 2017;27(5):595-596. DOI: 10.1089/thy.2017.0154.
  6. Saenko VA, Thomas GA, Yamashita S. Meeting report: the 5th International expert symposium in Fukushima on radiation andhealth. Environ Health 2017, 16(1):3. DOI: 10.1186/s12940-017-0211-y.
  7. Matsuse M, Yabuta T, Saenko V, Hirokawa M, Nishihara E, Suzuki K, Yamashita S, Miyauchi A, Mitsutake N. TERT promoter mutations and Ki-67 labeling index as a prognostic marker of papillary thyroid carcinomas: combination of two independent factors. Scientific Rep 2017, 7:41752 DOI: 10.1038/srep41752. PMID: 28150740.
  8. Nikitski A, Rogounovitch T, Bychkov A, Takahashi M, Yoshiura K, Mitsutake N, Kawaguchi T, Matsuse M, Drozd V, Demidchik Yu, Nishihara E, Hirokawa M, Miyauchi A, Rubanovich A, Matsuda F, Yamashita S, Saenko V. Genotype analyses in the Japanese and Belarusian populations reveal independent effects of rs965513 and rs1867277 but do not support the role of FOXE1 polyalanine tract length in conferring risk for papillary thyroid carcinoma.Thyroid 2017;27(2):224-235. DOI: 10.1089/thy.2015.0541.
  9. Takamura N, Orita M, Saenko V, Yamashita S, Nagataki S, Demidchik Yu. Radiation and risk of thyroid cancer: Fukushima and Chernobyl. Lancet Diabetes Endocrinol 2016;4(8):647.
  10. Nikitski A, Saenko V, Shimamura M, Nakashima M, Matsuse M, Suzuki K, Rogounovitch T, Bogdanova T, Shibusawa N, Yamada M, Nagayama Y, Yamashita S, Mitsutake N. Targeted Foxe1 overexpression in mouse thyroid causes the development of multinodular goiter but does not promote carcinogenesis. Endocrinology 2016;157(5):2182-2195. DOI: 10.1210/en.2015-2066.
  11. Mussazhanova Z, Akazawa Y, Matsuda K, Shichijo K, Miura S, Otsubo R, Oikawa M, Yoshiura KI, Mitsutake N, Rogounovitch T, Saenko V, Kozykenova Z, Zhetpisbaev B, Shabdarbaeva D, Sayakenov N, Amantayev B, Kondo H, Ito M, Nakashima M. Association between p53-binding protein 1 expression and genomic instability in oncocytic follicular adenoma of the thyroid. Endocr J 2016;63(5):457-467. DOI: 10.1507/endocrj.EJ15-0629.
  12. Иванов В.К., Кащеев В.В., Чекин С.Ю., Максютов М.А., Туманов К.А., Меняйло А.Н., Власов О.К., Кочергина Е.В., Кащеева П.В., Щукина Н.В., Галкин В.Н., Каприн А.Д., Саенко В.А., Ямасита С. Рак щитовидной железы: уроки Чернобыля и их применение к ситуации в Фукусиме.
    «Радиация и риск». 2016. Том 25. № 2. C. 5-19.
  13. В.А. Саенко. Молекулярно-генетические особенности рака щитовидной железы после Чернобыля. Медицинские радиологические последствия Чернобыля: прогноз и фактические данные спустя 30 лет. Обнинск: МРНЦ им. А.Ф. Цыба – филиал ФГБУ «НМИРЦ» Минздрава России. 2016. C. 187.
  14. Takamura N., Orita M., Saenko V., Yamashita S., Nagataki S., Demidchik Y. Misrepresented risk of thyroid cancer in Fukushima - authors' reply. Lancet Diabetes Endocrinol. 2016 Dec;4(12):970-971.
  15. Масабаева М.Р., Аукенов Н.Е., Мусажанова Ж.Б., Саенко В. А., Рогунович Т.И., Шаймарданов Н.К., Курманова Б.Р., Баркибаева Н.Р., Рахыпбеков Т.К., Yamashita Shunichi. Генетический полиморфизм в районе гена II17A: связь с хроническим вирусным гепатитом и прогрессированием к циррозу печени в казахской популяции. Вопросы вирусологии. 2016. Т. 61. № 5. С. 212-219.
  16. Mitsutake N., Fukushima F., Matsuse M., Rogounovitch T., Saenko V., Uchino S., Ito M., Suzuk K., Suzuki S., Yamashita S. BRAF(V600E) mutation is highly prevalent in thyroid carcinomas in the young population in Fukushima: a different oncogenic profile from Chernobyl. Sci Rep. 2015 Nov; 20(5):16976.
  17. Mitsutake N, Fukushima T, Matsuse M, Rogounovitch T, Saenko V, Uchino S, Ito M, Suzuki K, Suzuki S, Yamashita S. BRAFV600E mutation is highly prevalent in thyroid carcinomas in the young population in Fukushima: a different oncogenic profile from Chernobyl. Scientific Rep 2015, 5:16976. DOI: 10.1038/srep16976.
  18. Drozd VM, Saenko VA, Brenner AV, Drozdovitch V, Pashkevich VI, Kudelsky AV, Demidchik YE, Branovan I, Shiglik N, Rogounovitch TI, Yamashita S, Biko J, Reiners C. Major Factors Affecting Incidence of Childhood Thyroid Cancer in Belarus after the Chernobyl Accident: Do Nitrates in Drinking Water Play a Role? PLoS One 2015, 10(9):e0137226. DOI:10.1371/journal.pone.0137226.
  19. Sahasrabudhe R, Estrada A, Lott P, Martin L, Polanco Echeverry G, Velez A, Neta G, Takahasi M, SaenkoV, Mitsutake N; JTCMS Consortium, Jaeguer E, Duque CS, Rios A, Bohorquez M, Prieto R, Criollo A, Echeverry M, Tomlinson I; CORGI Consortium; TCUKIN Consortiums, Carmona LG. The 8q24 rs6983267G variant is associated with increased thyroid cancer Endocr Relat Cancer 2015;22(5):841-849. DOI: 10.1530/ERC-15-0081.
  20. Rogounovitch TI, Bychkov A, Takahashi M, Mitsutake N, Nakashima M, Nikitski AV, Hayashi T, Hirokawa M, Ishigaki K, Shigematsu K, Bogdanova T, Matsuse M, Nishihara E, Minami S, Yamanouchi K, Ito M, Kawaguchi T, Kondo H, Takamura N, Ito Y, Miyauchi A, Matsuda F, Yamashita S, Saenko VA. The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population. Thyroid 2015, 25(3):333-340. DOI: 10.1089/thy.2014.0431.
  21. Suzuki K, Mitsutake N, Saenko V, Yamashita S. Radiation signatures in childhood thyroid cancers after the Chernobyl accident: possible roles of radiation in carcinogenesis. Cancer Science 2015, 106(2):127-133. DOI: 10.1111/cas.12583. DOI: 10.1111/cas.12583, PMID: 25483826.
  22. Stanojevic B, Saenko V, Todorovic L, Petrovic N, Zivaljevic V, Paunovic I, Nakashima M, Yamashita S, Dzodic R. Low VHL mRNA expression is associated with more aggressive tumor features of papillary thyroid carcinoma. PLOS ONE 2014;9(12):e114511. DOI: 10.1371/journal.pone.0114511, PMID: 25490036.
  23. Leonova TA, Drozd VM, Saenko VA, Mine M, Biko J, Rogounovitch TI, Takamura N, Reiners C, Yamashita S. Bone mineral density in treated at a young age for differentiated thyroid cancer after Chernobyl female patients on TSH-suppressive therapy receiving or not Calcium-D3 supplementation. Endocr J 2015, 62(2):173-182. DOI: 10.1507/endocrj.EJ14-0408. PMID: 25374130.
  24. Ito M, Bogdanova T, Saenko V, Rogounovitch T, Mitsutake N, Kondo H, Maeda S, Nakashima M, Yamashita S. Morphological difference in adultthyroid papillary carcinoma between Japan and Ukraine. Endocr J 2014, 61(12):1221-1228. DOI: 10.1507/endocrj.EJ14-0239.
  25. Tronko MD, Saenko VA, Shpak VM, Bogdanova TI, Suzuki S, Yamashita S. Age Distribution of Childhood ThyroidCancer Patients in Ukraine After Chernobyl and in Fukushima After the TEPCO-Fukushima Daiichi NPP Accident. Thyroid 2014;24(10):1547-1548.
  26. Orim F, Bychkov A, Shimamura M, Nakashima M, Ito M, Matsuse M, Kurashige T, Suzuki K, SaenkoV, Nagayama Y, Yamashita S, Mitsutake N. Thyrotropin signaling confers more aggressive features with higher genomic instability on BRAFV600E-induced thyroid tumors in a mouse model. Thyroid 2014;24(3):502-510.
  27. Mussazhanova Z, Miura S, Stanojevic B, Rougounovitch T, Saenko V, Shiraishi T, Kurashige T, Shichijo K, Kaneko K, Takahashi H, Ito M, Nakashima M. Radiation-associated small cell neuroendocrine carcinoma of the thyroid: a case report with molecular analyses. Thyroid 2014;24(3):593-598.
  28. Fuzik MM, Prysyazhnyuk AY, Shibata Y, Romanenko AY, Fedorenko ZP, Gudzenko NA, Gulak LO, Trotsyuk NK, Goroh YL, Khukhrianska OM, Sumkina OV, Saenko VA, Yamashita S. Age and gender patterns of thyroid cancer incidence in Ukraine depending on thyroidradiation doses from radioactive iodine exposure after the Chornobyl NPP accident. Probl Radiac Med Radiobiol 2013;Sep;18:144-155.
  29. Mussazhanova Z, Matsuda K, Naruke Y, Mitsutake N, Stanojevic B, Rougounovitch T, Saenko V, Suzuki K, Nishihara E, Hirokawa M, Ito M, Nakashima M. Significance of p53-binding protein 1 (53BP1) expression in thyroid papillary microcarcinoma: association withBRAFV600Emutational status. Histopathology 2013;63(5):726-734.
  30. Bychkov A, Saenko V, Nakashima M, Mitsutake N, Rogounovitch T, Nikitski A, Orim F, Yamashita S. Patterns of FOXE1 expression in papillary thyroid carcinoma by immunohistochemistry. Thyroid 2013; 23(7):817-828.
  31. Matsuse M, Mitsutake N, Tanimura S, Ogi T, Nishihara E, Hirokawa M, Fuziwara CS, Saenko VA, Suzuki K, Miyauchi A, Yamashita S. Functional characterization of the novel BRAF complex mutation, BRAF(V600delinsYM), identified in papillarythyroid  Int J Cancer 2013;132(3):738-743.
  32. Tronko M, Bogdanova T, Saenko V, Thomas GA, Likhtarov I, Yamashita S. Thyroid cancer in Ukraine after Chernobyl: dosimetry, epidemiology, pathology, molecular biology. IN-TEX, Nagasaki, 175 pp., 2014.
  33. Demidchik YuE, Fridman MV, Mankovskaya S, Krasko O, Schmid KW, Lam AK, Moiseev P, Saenko VA , Yamashita S. Post-Chernobyl Pediatric Papillary Thyroid Carcinoma in Belarus: Histopathological Features, Treatment Strategy, and Long-Term Outcome (Chapter 5). In: Thyroid Cancer and Nuclear Accidents. Long-Term Aftereffects of Chernobyl and Fukushima. Eds.: Yamashita S, Thomas G. Typeset MPS Limited, Chennai, Elsevier, pp. 49-58, 2017.
  34. Drozd VM, Fridman MV, Saenko VA, Demidchik YuE, Platonova T, Branovan I, Shiglik N, Rogounovitch TI, Yamashita S, Biko J, Reiners Ch. Clinical Aspects of Pediatric Thyroid Cancer and Follow-Up of Patients in Belarus Following the Chernobyl Accident (Chapter 6). In: Thyroid Cancer and Nuclear Accidents. Long-Term Aftereffects of Chernobyl and Fukushima. Eds.: Yamashita S, Thomas G. Typeset MPS Limited, Chennai, Elsevier, pp. 59-66, 2017. DOI: 10.1016/B978-0-12-812768-1.00006-X.
  35. Bogdanova T, Saenko VA, Shpak V, Zurnadzhy L, Voskoboynyk L, Dekhtyarova T, Burko S, Gulii T, Yamashita S, Tronko M. Long-Term Analysis of the Incidence and Histopathology of Thyroid Cancer in Ukraine in Adult Patients Who Were Children and Adolescents at the Time of the Chernobyl Accident (Chapter 7). In: Thyroid Cancer and Nuclear Accidents. Long-Term Aftereffects of Chernobyl and Fukushima. Eds.: Yamashita S, Thomas G. Typeset MPS Limited, Chennai, Elsevier, pp. 67-76, 2017.
  36. Ivanov V, Kashcheev V, Chekin S, Maksioutov M, Tumanov K, Menyajlo A, Vlasov O, Kochergina E, Kashcheeva P, Shchukina N, Korelo A, Seleva N, Galkin V, Kaprin A, Saenko VA, Yamashita S. Results of the Thyroid Cancer Epidemiological Survey in Russia Following the Chernobyl Accident (Chapter 9). In: Thyroid Cancer and Nuclear Accidents. Long-Term Aftereffects of Chernobyl and Fukushima. Eds.: Yamashita S, Thomas G. Typeset MPS Limited, Chennai, Elsevier, pp. 87-96, 2017.
  37. Rumiantsev PO, Saenko VA and Dedov II. Influence of Radiation Exposure and Ultrasound Screening on the Clinical Behavior of Papillary Thyroid Carcinoma in Young Patients (Chapter 10). In: Thyroid Cancer and Nuclear Accidents. Long-Term Aftereffects of Chernobyl and Fukushima. Eds.: Yamashita S, Thomas G. Typeset MPS Limited, Chennai, Elsevier, pp. 97-107, 2017. DOI: 10.1016/B978-0-12-812768-1.00010-1.
  38. Parshin V, Tsyb A, Yamashita S. Ultrasound diagnosis of thyroid disease in Russia and Chernobyl. Scientific Editors:Saenko V, Suzuki S. Omura Print, Nagasaki-Omura, 147 pp., 2013.
  39. RogounovitchT, SaenkoV. Single-nucleotidepolymorphismspredisposingtothyroidcancer: majorfindingsofgenome-wideassociationstudies. Thyroid Cancer Explore 2017;3(1):25-31.
  40. Bychkov A, Saenko V, Rogounovitch T, Nakashima M, Mitsutake N, Yamashita S. Particularities of FOXE1 expression in papillary thyroid carcinoma. In: Proceedings of the 53-rd Atomic Bomb Consequence Research Meeting, Nagasaki Med J, pp. 119-122.