НАУЧНЫЙ И ИНФОРМАЦИОННО-АНАЛИТИЧЕСКИЙ ЖУРНАЛ

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

Медицинская радиология и радиационная безопасность. 2015. Том 60. № 2. С. 66-81

ОБЗОР

Ю.Н. Корыстов

АНАЛИЗ РАДИОБИОЛОГИЧЕСКИХ ДАННЫХ ДЛЯ ОЦЕНКИ КАНЦЕРОГЕННОГО РИСКА МАЛЫХ ДОЗ ИОНИЗИРУЮЩЕЙ РАДИАЦИИ

Институт теоретической и экспериментальной биофизики РАН, Московская обл., Пущино, e-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра.

СОДЕРЖАНИЕ

1. Введение

2. Об экспериментальном обосновании линейной беспороговой дозовой зависимости стохастических эффектов радиации

3. Передача мишени дозы, поглощённой вне клетки: факторы, которые могут увеличить объём мишени и снизить эффективную дозу

3.1. Эффект облучённой среды

3.2. Эффект свидетеля

4. Индуцируемая радиацией нестабильность генома

5. Репарация ДНК и элиминация мутантных клеток: факторы, которые могут уменьшить объём мишени и увеличить эффективную дозу

5.1. Роль репарации ДНК в радиационном канцерогенезе

5.2. Стимуляция противоопухолевого иммунитета и апоптоза малыми дозами радиации: активация элиминации трансформированных клеток и подавление роста опухолей

6. Зависимость стохастических эффектов радиации от мощности дозы

7. Влияние малых доз ионизирующей радиации на канцерогенез: экспериментальные данные

8. Выводы

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Для цитирования: Корыстов Ю.Н. Анализ радиобиологических данных для оценки канцерогенного риска малых доз ионизирующей радиации. Медицинская радиология и радиационная безопасность. 2015. Т. 60. № 2. С. 66-81.

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