Medical Radiology and Radiation Safety. 2019. Vol. 64. No. 4. P. 56–63

DOI: 10.12737/article_5d1b46c9133942.84705406

Е.S. Sukhikh1,2, L.G. Sukhikh2, E.L. Malikov2, P.V. Izhevsky3, I.N. Sheino3, A.V. Vertinsky1,2, A.A. Baulin2,4

Uncertainty of Measurement Absorbed Dose by Gafchromic EBT3 Dosimeter for Clinical Electron and Photon Beams of Medical Accelerators

1. Tomsk Regional Oncology Centre, Tomsk, Russia. E-mail: Этот адрес электронной почты защищен от спам-ботов. У вас должен быть включен JavaScript для просмотра. ;
2. National Research Tomsk Polytechnic University, Tomsk, Russia;
3. A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia;
4. Gamma Clinic High-Precision Radiology Centre (Gamma Medtechnology Ltd)., Obninsk, Russia

Е.S. Sukhikh – Head of Department, Assistant Professor, PhD Phys.-Math., Member of ESTRO, Member of EFOMP, Member of ISRS;
L.G. Sukhikh – Director of Research School of Physics, Dr. Sci. Phys-Math.;
E.L. Malikov – Researcher;
P.V. Izhevsky – Leading Researcher, Assistant Professor, PhD Med.;
I.N. Sheino – Head of the Lab., PhD Phys-Math.;
A.V. Vertinsky – Medical Physicist, PhD student;
A.A. Baulin – Medical Physicist, PhD student, Member of ISRS


Purpose: Investigation of the relative errors of absorbed dose measurement based on polymer films Gafchromic EBT3 for clinical electron and photon beams of medical accelerators.

Material and methods: Polymer Gafchromic EBT3 films were calibrated using different radiation beams, namely photon and electron beams of Elekta Axesse medical accelerator with beam energy equal to 10 MV and 10 MeV, correspondingly, and electron beam of a betatron for intraoperative radiotherapy with beam energy equal to 6 MeV. The film pieces were irradiated by the uniform dose field in the dose range from 0.5 to 40 Gy. The dose value was controlled by cylindrical ionization chamber on Elekta Axesse accelerator and by the Markus parallel-plate ionization chamber on betatron. The irradiated films were scanned using Epson Perfection V750 Pro flatbed scanner in 16 bit RGB color mode with 150 dpi resolution. The red and green channels were used for further analysis. The central part of each film was used for calculation of average values of net optical density and its root-mean-square. As a result, the calibration curves, i.e. dependence on the reference absorbed dose measured by ionization chamber on the net optical density were constructed taking into account uncertainties of dose measurement and optical density measurement.

Results: The relative uncertainty for the dose measurement lies within 7 % for low doses (less than 1 Gy) and within 4 % for higher doses. The green channel is less sensitive to the radiation, but its relative uncertainty values are in general 1–2 % lower than the ones for the red channel. The use of different calibration sources results in different calibration curves with difference up to ± 6 % for the green channel.

Conclusion: The polymer Gafchromic EBT3 films can be used for absorbed dose measurement for the doses not less than 0.5 Gy. For lower dose values the dose measurement uncertainty caused by statistical reasons amounts 15 %. For dose values of about 1 Gy and higher the dose measurement uncertainty amounts 5 % that allows to use the films for transverse and longitudinal prescription treatment dose distribution measurement with very high spatial resolution.

Key words: radiation therapy, Gafchromic EBT3 film, clinical dosimetry, medical accelerators, absorbed dose, uncertainties


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For citation: Sukhikh ЕS, Sukhikh LG, Malikov EL, Izhevsky PV, Sheino IN, Vertinsky AV, Baulin AA. Uncertainty of Measurement Absorbed Dose by Gafchromic EBT3 Dosimeter for Clinical Electron and Photon Beams of Medical Accelerators. Medical Radiology and Radiation Safety. 2019;64(4):56–63. (English and Russian).

DOI: 10.12737/article_5d1b46c9133942.84705406

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