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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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Медицинская радиология и радиационная безопасность. 2026. Том 71. № 4
DOI: 10.33266/1024-6177-2026-71-4-5-11
А.К. Чигасова1,2,3, А.Н. Осипов1,2
АНАЛИЗ ФОКУСОВ ФОСФОРИЛИРОВАНОГО ГИСТОНА Н2АХ В РАДИОБИОЛОГИИ: ОБЗОР ЛИТЕРАТУРЫ
1 Федеральный медицинский биофизический центр им. А.И. Бурназяна ФМБА России, Москва
2 Федеральный исследовательский центр химической физики им. Н.Н. Семенова РАН, Москва
3 Институт биохимической физики им. Н.М. Эмануэля РАН, Москва
Контактное лицо: Андреян Николаевич Осипов, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
СОДЕРЖАНИЕ
Введение
Общая характеристика Н2АХ
Природа спонтнанных (фоновых) фокусов γH2AX
Образование фокусов γH2AX в облученных клетках
Влияние структуры хроматина на образование и деградацию радиационно-индуцированных фокусов γH2AX
Влияние фазы клеточного цикла на образование и деградацию радиационно-индуцированных фокусов γH2AX
Остаточные радиационно-индуцированные фокусы γH2AX
Заключение
Ключевые слова: γH2AX, повреждения ДНК, репарация ДНК, ионизирующие излучение
Для цитирования: Чигасова А.К., Осипов А.Н. Анализ фокусов фосфорилированного гистона H2AX в радиобиологии: обзор литературы // Медицинская радиология и радиационная безопасность. 2026. Т. 71. № 4. С. 5–11. DOI:10.33266/1024-6177-2026-71- 4-5-11
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Поступила: 20.03.2026. Принята к публикации: 25.04.2026.