JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 57–62
Analysis of Relation Between Lifetime Rates and Incorporation of Plutonium-239
in Atomic Production Workers Regarding Tumor and Non-Tumor Causes of Death
V.I. Tel’nov, I.V. Legkikh, P.V. Okatenko
Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia.
Contact person: Vitaly Ivanovich Telnov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: The objective of the study was in quantitative assessment of the effect of internal exposure to lifetime in Mayak PA workers based on analyzing dependence of certain lifetime rates on incorporation of plutonium-239 regarding tumor and non-tumor causes of death.
Material and methods: The cohort of deceased Mayak PA workers employed in1948–1958 with known Pu-239 body burden comprising 2343 individuals, of them 1739 males and 604 females, was investigated. Using regression analysis we have assessed dependence of general lifetime and lifetime after start of work as well as of proportion of individuals who did not survive until standard age in general and after start of work from incorporated Pu-239 separately for workers of different age regarding tumor and non-tumor causes of death. Statistical values were defined using Statistica software.
Results: It was stated that in case of increase of plutonium-239 body burden in males and females reliably increased shortening of lifetime and lifetime after start of work was observed as well as increased proportion of individuals who did not survive until standard lifetime rate and until standard lifetime after start of work. Reliable regression equations for dependence of the studied lifetime values from radionuclide incorporation rate were obtained based on regression analysis. Generally, changes in the studied characteristics of lifetime after start of work were more evident than in general lifetime characteristics.
Conclusion: Reliable dependence of shortening of lifetime and lifetime after start of work, of increased proportion of individuals who did not survive until standard lifetime and lifetime after start of work among Mayak PA workers of different gender from incorporation of plutonium-239 regarding tumor and non-tumor causes of death was stated. Dependence of lifetime after start of work on incorporated plutonium-239 was higher than of general lifetime that could be probably due to direct contact of workers with radionuclide after start of work. The results obtained indicate feasibility of using not only general lifetime but also lifetime after start of work in assessment of lifetime among workers who are in contact with production hazardous factors.
Кey words: Mayak PA workers, plutonium-239, tumor and non-tumor causes of death, lifetime rates, regression analysis
For citation: Tel’nov VI, Legkikh IV, Okatenko PV. Analysis of Relation Between Lifetime Rates and Incorporation of Plutonium-239 in Atomic Production Workers Regarding Tumor and Non-Tumor Causes of Death. Medical Radiology and Radiation Safety. 2021;66(6): 57–62.
DOI: 10.12737/1024-6177-2021-66-6-57-62
References
1. Ed. Valentin J. ICRP Publication 103: Recommendations of the ICRP. Annals of the ICRP. Elsevier, 2007. 332 p.
2. Yarmonenko SP, Vaynson AA. Human and Animal Radiobiology.: Study Guide. Moscow, Vys’shaya Shcola Publ., 2004. 549 p. (In Russian).
3. Moskalev YI. Late Effects of Ionizing Radiation Exposure. Moscow, Meditsina Publ., 1991. 464 p. (In Russian).
4. Buldakov LA, Lyubchanskiy ER, Moskalev YI, Nifatov AP. Aspects of Plutonium Toxicology. Moscow, Atomizdat Publ., 1969. 368 p. (In Russian).
5. Kalistratova VS, Belyaev IK, Zhorova ES, Parfenova IM, Tishchenko GS. Radiobiology of Incorporated Radionuclides. 2nd Edition. Ed. Kalistratova V.S. Moscow, A.I. Burnazyan FMBC Publ., 2016. 556 p. (In Russian).
6. Yoshinaga Sh., Mabuchi K, Sigurdson AJ, Doody MM, Ron E. Cancer Risks Among Radiologists and Radiologic Technologists: Review of Epidemiologic Studies Radiology. 2004;233;2:313–321.
7. Cologne JB, Preston DL. Longevity of Atomic-Bomb Survivors. Lancet. 2000;356:303–311.
8. Mohan AK, Hauptmann M, Freedman DM, Ron E, Matanoski GM, Lubin JH et al. Cancer and Other Causes of Mortality among Radiologic Technologists in the United States. Int. J. Cancer. 2003;103;2:259–267.
9. Hauptmann M, Mohan AK, Doody MM, Linet MS, Mabuchi K. Mortality from Diseases of the Circulatory System in Radiologic Technologists in the United States. Am. J. Epidemiol. 2003;157;3:239–248.
10. Warren S. Longevity and Causes of Death from Irradiation in Physicians. J. Am. Med. Assoc. 1956;162;5:464–468.
11. Berrington A, Darby SC, Weiss HA, Doll R. 100 years of Observation on British Radiologists: Mortality from Cancer and Other Causes 1897-1997. Br. J. Radiol. 2001;74;882:507–519.
12. Wang JX, Inskip PD, Boice JDJr, Li BX, Zhang JY, Fraumeni JFJr. Cancer Incidence among Medical Diagnostic X-ray Workers in China, 1950 to 1985. Int. J. Cancer. 1990;45;5:889–895.
13. Shimizu Y, Kodama K, Nishi N., et al. Radiation Exposure and Circulatory Disease Risk: Hiroshima and Nagasaki Atomic Bomb Survivor Data, 1950-2003. BMJ. 2010;340:b5349. doi: 10.1136/bmj.b5349.
14. Little MP, Tawn EJ, Tzoulaki I., et al. Review and Meta-Analysis of Epidemiological Associations Between Low/Moderate Doses of Ionizing Radiation and Circulatory Disease Risks, and Their Possible Mechanisms. Radiat Environ. Biophys. 2010;49;2:139–153. doi: 10.1007/s00411-009-0250-z.
15. Vrijheid M, Cardis E, Ashmore P, et al. Mortality from Diseases other than Cancer Following Low Doses of Ionizing Radiation: Results from the 15-Country Study of Nuclear Industry Workers. International Journal of Epidemiology. 2007;36:1126–1135. doi:10.1093/ije/dym138.
16. Polednak AP, Stehney AF, Rowland RE. Mortality among Women First Employed Before 1930 in the U.S. Radium Dial-Painting Industry. A Group Ascertained from Employment Lists. Am. J. Epidemiol. 1978;107;3:179–195.
17. Spiess H. Life-Span Study on Late Effects of 224Ra in Children and Adults. Health Phys. 2010;99;3:286–291. doi: 10.1097/HP.0b 013e3181cb857f.
18. Smith PG, Doll R. Mortality among Patients with Ankylosing Spondylitis after a Single Treatment Course with X Rays. BMJ. 1982;284;6314:449–460.
19. Saurov MM, Gneusheva GI, Kosenko MM. Demographic Studies in Radiation Hygiene. Ed. Buldakov L.A. Moscow Publ., 1987. 226 p. (In Russian).
20. Yakovleva VP, Kosenko MM. Lifetime in Population Subject to Chronic Radiation Exposure. Medical-Biological and Ecological Consequences of Radioactive Contamination of Techa River. Ed. Akleev A.V., Kiselev M.F. 2nd Edition, Revised and Updated. Moscow Publ., 2001. P. 298–304. (In Russian).
21. Tel’nov VI. Plutonium and Lifetime Shortening in Professional Workers. Hygiene and Sanitary. 2015;94;3:56–60. (In Russian).
22. Tel’nov VI, Tret’yakov FD, Okatenko PV. Plutonium-239 Incorporation and Lifetime Shortening in Mayak PA Workers Regarding Tumor and Non-Tumor Causes of Death. Medical Radiology and Radiation Safety. 2017;62;2:28–34. (In Russian).
23. Gavrilov LA, Gavrilova NS. Lifetime Biology. 2nd edition. Moscow, Nauka Publ., 1991. 280 p. (In Russian).
24. Human Mortality Database. Electronic Source: http://www.mortality.org.
25. Russian Demographic Annuary. 2017: Statistical Digest. Rosstat. Moscow Publ., 2017. 263 p. (In Russian).
26. Tel’nov VI, Tret’yakov FD. Medical and Demographic Aspects of Public Health in Population of the Atomic Production Monocity Ozersk. Public Health in Industrial Monocities: Program and Material of the Inter-Disciplinary Conference with International Participation. April 24-25, 2014. Chelyabinsk Publ., 2014. P. 104-120. (In Russian).
27. Ed. Rybakovskiy LL. Practical Demography Moscow TsSP Publ., 2005. 280 p. (In Russian).
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The author declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. The article was prepared by one author.
Article received: 17.07.2021.
Accepted for publication: 05.09.2021