JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 1
Influence of Drinking Water Quality
in the Course of Radiation Damage Following Fractionated Irradiation
O.V. Nikitenko1,2, I.E. Andrianova1, T.M. Bychkova1,2,
N.M. Stavrakova1, I.M. Parfenova1, T.A. Karaulova1,
A.V. Gordeev1, A.A. Ivanov1,2,3
1A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
2Institute of Biomedical Problems, Russian Academy of Sciences, Moscow, Russia
3Joint Institute for Nuclear Research, Dubna, Russia
Contact person: Nikitenko Olga Vasilievna, This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Assessment of the role of various factors in the formation of radioresistance is an important section of radiobiology, radiation medicine, including radiation therapy for hematological oncological diseases. The quality of drinking water, as it turned out, can significantly affect the radio resistance. Against the background of studying the antiradiation properties of various types of water, differing in mineral and isotopic composition, the problem of the influence of tap water on the course of radiation injury remained underestimated. This circumstance determined the purpose of the work: to compare the effectiveness of the effect of fractionated total X-ray irradiation in lethal doses, simulating total therapeutic irradiation of oncohematological patients, when consuming tap water and highly purified artificially mineralized tap water in an experiment on mice.
Materials and Methods: Female ICR (CD-1) mice were irradiated with moderately lethal doses of fractionated (daily 4 × 2.2 Gy
and 4 × 2.3 Gy) X-ray irradiation. After exposure, half of the mice received tap water as drinking water, and the other half received artificially mineralized drinking water.
Results: Keeping animals on tap water statistically significantly reduced the survival rate of mice under fractionated irradiation (χ2 = 3.88, p <0.05, log-rank test p = 0.049) compared with animals receiving artificially mineralized distilled water. In addition, in the group of mice that received tap water, an increase in the rate of death of mice and a lower safety of the group weight of animals during the development of acute radiation injury were noted.
Conclusion: Tap water, used as drinking water, increases the damaging effect of radiation with fractionated X-ray irradiation of mice.
Keywords: X-ray exposure, tap water, artificially mineralized distilled water, survival, mortality, mouse
For citation: Nikitenko OV, Andrianova IE, Bychkova TM, Stavrakova NM, Parfenova IM, Karaulova TA, Gordeev AV, Ivanov AA. Influence of Drinking Water Quality in the Course of Radiation Damage Following Fractionated Irradiation. Medical Radiology and Radiation Safety. 2022;67(1):5-10. (In Russian)
DOI: 10.12737/1024-6177-2022-67-1-5-10
References
1. Yagunov A.S., Reeves G.I., Tokalov S.V., Chukhlovin A.B., Afanassiev B.V. Animal Studies of Residual Hematopoietic and Immune System Injury from Low Dose/Low Dose Rate Radiation and Heavy Metals. Bethesda, MD, Armed Forces Radiobiology Research Institute, 1998. DOI: 10.13140/2.1.3584.0007.
2. Carpenter D.O., Bushkin-Bedient S. Exposure to Chemicals and Radiation During Childhood and Risk for Cancer Later in Life. J. Adolesc Health. 2013;52;5:21-29. doi:10.1016/j.jadohealth.2013.01.027.
3. Vacek A., Sikulová J., Bartonícková A. Radiation Resistance in Mice Increased Following Chronic Application of Li2CO3. Acta Radiol. Oncol. 1982;21;5:325-330. doi:10.3109/02841868209134023.
4. Chlorinated Drinking-Water; Chlorination By-Products; Some Other Halogenated Compounds; Cobalt and Cobalt Compounds. IARC Monogr Eval Carcinog Risks Hum. International Agency for Research on Cancer (IARC) Working Group. Lyon, 1991;52:45-399.
5. Melkova K.N., Gorbunova N.V., CHernyavskaya T.Z., Baranov A.YE., Pushkareva S.G., Frolov G.P., et. al. Total Body Irradiation Conditioning for Bone Marrow Transplantation. Klinicheskaya onkogematologiya. Fundamentalnyye issledovaniya i klinicheskaya praktika = Clinical Oncohematology. Basic Research and Clinical Practice. 2012;5;2:96-114 (In Russ.).
6. Sanitary and Epidemiological Rules and Regulations SanPiN 2.1.4.1074-01 Drinking Water. Hygienic Requirements for Water Quality of Centralized Drinking Water Supply Systems. Quality Control. Hygienic Requirements for Ensuring the Safety of Hot Water Supply Systems (In Russ.).
7. Kaplan E.L., Meier P. Non-Parametric Estimation from Incomplete Observations. J. Am. Stat. Assoc. 1958;53;282:457–481.
8. Sacher G.A. On the Statistical Nature of Mortality, with Especial Reference to Chronic Radiation Mortality. Radiology. 1956;67;2:250-258. doi: 10.1148/67.2.250.
9. International Guiding Principles for Biomedical Research Involving Animals. CIOMS. Geneva, 1985.
10. Guidelines for Drinking Water Quality. 4th Edition. WHO Library Cataloging in Publication Data. 2011. P. 584.
11. Van Trigt R. Lazer spectrometry for stable isotope analysis of water // Biomedical and paleoclimatological applications. Groningen, University library groningen, 2002. P. 192
12. Rakhmanin Yu.A. Biophysics of Water: Quantum Nonlocality in Water Treatment Technologies, the Regulatory Role of Associated Water in Cellular Metabolism, Regulation of Bioenergetic Activity of Drinking Water. Ed. Rakhmanin Yu.A., Stekhin A.A., Yakovleva G.V. Moscow, URSS Publ., 2016. 346 p. (In Russ.).
13. Ivanov A.A., Andrianova I.E., Mal'tsev V.N., Shalnova G.A., Stavrakova N.M., Bulynina T.M., et al. The Impact of Drinking Water of Various Quality on Intact and Irradiated Mice. Gigiyena i Sanitariya = Hygiene and Sanitation. 2017;96;9:854-860. DOI: 10.18821/0016-9900-2017-96-9-854-860 (In Russ.).
14. Laissue J.A., Altermatt H.J., Bally E., Gebbers J.O. Protection of Mice from Whole Body Gamma Irradiation by Deuteration of Drinking Water: Hematologic Findings. Exp. Hematol. 1987;15;2:177-180.
15. Ivanov A.A., Ushakov I.B., Kulikova Ye.I., Kryuchkova D.M., Severyukhin Yu.S., Vorozhtsova S.V., Abrosimova A.N., Gayevskiy V.A., Sinyak Yu.Ye., Grigoryev A.I. Light-Isotope Water as a Therapeutic Agent for Acute Radiation Disease. Aviakosmicheskaya i Ekologicheskaya Meditsina = Aerospace and Environmental Medicine. 2013;47;5:40-44 (In Russ.).
16. Abrosimova A.N., Rakov D.V., Sinyak Yu.E. Effect of "Light Water" on the Development of Lens Opacity in Mice after Repeated γ-Irradiation at Low Doses. Aviakosmicheskaya i Ekologicheskaya Meditsina = Aerospace and Environmental Medicine. 2009;3;2:29-32 (In Russ.).
17. Kulikova Ye.I., Kryuchkova D.M., Severyukhin Yu.S., Gayevskiy V.N., Ivanov A.A Radiomodifying Properties of Deuterium-Depleted Water with Poor Content of Heavier Isotopes of Oxygen. Aviakosmicheskaya i Ekologicheskaya Meditsina = Aerospace and Environmental Medicine. 2012;46;6:45-50 (In Russ.).
18. Kryuchkova D.M., Andrianova I.Ye., Kovalenko M.A., et al. Effect of a Mineral-Organic Complex on Mice Radioresistance. Aviakosmicheskaya i Ekologicheskaya Meditsina = Aerospace and Environmental Medicine. 2013;47;5:37-40 (In Russ.).
19. Cantor K.P., Hoover R., Hartge P., et al. Bladder Cancer, Drinking Water Source, and Tap Water Consumption: a Case-Control Study. J. Natl. Cancer Inst. 1987;79;6:1269-1279.
20. Ishidate M.Jr., Sofuni T., Yoshikawa K., Hayashi M., et al. Primary Mutagenicity Screening of Food Additives Currently Used in Japan. Food and Chemical Toxicology 1984;22;8:623-636. doi.org/10.1016/0278-6915(84)90271-0.
21. Eltahawy N.A., Sarhan O.M., Hammad A.S., et al. Effects of Combined Exposure to Aluminum Chloride and γ-Radiation on Histological and Ultrastructure of Intestinal Paneth Cells. Radiat. Res. Appl. Sci. 2016;9:400-408. doi.org/10.1016/j.jrras.2016.05.007.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 12.11.2021.
Accepted for publication: 05.12.2021