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Medical Radiology and Radiation Safety. 2022. Vol. 67. № 2

Hyperthermia in Conservative and Palliative Treatment
of Oncological Patients. Part II. Whole Body Hyperthermia

O.K. Kurpeshev1, J. Van der Zee2

1Siberian Scientific Research Institute of Hyperthermia, Novosibirsk, Russia

2Erasmus Medical Centre, Cancer Institute, Rotterdam, The Netherlands

Contact person: Orazakhmet Kurpeshev, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

CONTENTS

The analysis of the results of the use of whole-body hyperthermia (WBH) in patients with locally advanced, recurrent and / or metastatic tumors, which, as a rule, are radio- and chemo-resistant. Most patients were incurable, in connection with which the treatment was mainly carried out with a palliative purpose. The analysis showed that the method alone or in combination with chemo- and radiation therapy has pronounced direct and palliative effects, in some cases it provides long-term control. However, WBH can have side effects. This necessitates further improvement of the method, development of a set of preventive measures, as well as improvement of equipment for heating and thermometry.

AbbREVIATIONS

BrCa – Breast cancer 

CE – Clinical effect

CR – complete response

CeCa – cervical cancer

CRCa – colo-rectal cancer

CT – chemotherapy

ECWBH – extracorporal WBH

HIPCT – hyperthermic intraperitoneal CT

IR – infrared radiation

IRWBH – IR whole body hyperthermia

IT – immunotherapy

LA – locally advanced

LCa – Lung cancer

LC – local control

ML – malignant limphomas

MМ – malignant mesetelioma

MSTDP – median survival time to disease progression

MST – multi-step therapy

MTS – metastases

HL – Hodgkin’s lymphoma

NSCLC – non small cell lung cancer

RT – radiation therapy

OR – objective response

OS – overall survival

OsSa – osteosarcoma

OvCa – ovarian cancer

PCa – pancreatic Cancer

PE – palliative effect

PR – partial response

RF – radiofreqency

RFWBH – radiofrequency WBH

SD – stabilization disease

SCLC – small cell lung cancer

STS – soft tissue sarcoma

TBRT – total body RT

TTD – tumor total dose

WBH – whole body hyperthermia

Keywords: general hyperthermia, palliative therapy, chemotherapy, radiation therapy, review

For citation: Kurpeshev OK, Van der Zee J. Hyperthermia in conservative and palliative treatment of oncological patients. Part ii. Whole body hyperthermia. Medical Radiology and Radiation Safety. 2022;67(2):43-58. doi: 10.33266/1024-6177-2022-67-2-43-58

 

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 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 30.11.2021. Accepted for publication: 30.03.2022.

 

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