JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
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The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2022. Vol. 67. № 2
Study of the Functional Relationship of the Brain in Patients
with Asymptomic Carotidal Senosis
Pospelova M.L., Efimtsev A.Y., Lepekhina A.S., Trufanov G.E., Alekseeva T.M., Ivanova N.E., Efimova M.Y., Voronin A.S.,
Makhanova A.M., Mikhalicheva A.A.
V.A. Almazov National Medical Research Centre, Sanct-Petersburgh, Russia
Contact person: A.S. Lepekhina, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To explore functional connectivity in patients with asymptomatic internal carotid arteries stenosis of more than 60% when using hirudotherapy.
Materials and methods: The analysis of the results of the examination of 15 patients aged 60 to 82 years with asymptomatic stenosis of the carotid arteries in the range of 60‒75 % was carried out. The patients underwent a course of hirudotherapy, consisting of 10 sessions. All patients underwent structural and functional magnetic resonance imaging with analysis of statistical data at rest, complaints and neurological status were assessed ‒ before and after the course of hirudotherapy.
Results: When using a course of hirudotherapy in patients with asymptomatic internal carotid arteries tenosis, when analyzing the neurological status and complaints, a significant improvement in well-being was noted. During functional magnetic resonance imaging, differences in functional connectivity between the medial prefrontal cortex and other areas of the brain were determined. Activation was noted in the main structures of the network of managerial control and identification of significance. Connectivity between the leading regions of the brain increased, which is a sign of improved brain activity.
Conclusion: Connectivity research can be used to study the functioning of brain networks and to determine the effectiveness of therapy. The course of hirudotherapy significantly changed the functional connectivity of the brain regions, the changes correlated with a decrease in the number of complaints. This work is a pilot and will be continued for the further development of treatment-and-prophylactic strategies with the inclusion of hirudotherapy in patients with a high risk of vascular accidents in a treatment.
Keywords: asymptomatic carotid stenosis, hirudotherapy, fMRI, connectome
For citation: Pospelova ML, Efimtsev AY, Lepekhina AS, Trufanov GE, Alekseeva TM, Ivanova NE, Efimova MY, Voronin AS, Makhanova AM, Mikhalicheva AA. Study of the functional relationship of the brain in patients with asymptomic carotidal senosis. Medical Radiology and Radiation Safety. 2022;67(2):59-63. (In Russian) doi: 10.33266/1024-6177-2022-67-2-59-63
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 30.11.2021. Accepted for publication: 30.03.2022.