JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2024. Vol. 69. № 4
DOI:10.33266/1024-6177-2024-69-4-71-76
E.I. Matkevich1, 2, Е.А. Ladik1, E.V. Bril1, O.S. Zimnyakova1, V.V. Bryukhov3
Assessment of Midbrain Structure Visualization with Modified 3 Tesla MRI Protocols for Enhanced Parkinson’s Disease Diagnosis
1 A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
2 RUDN University, Moscow, Russia
3 Research Center of Neurology, Moscow, Russia
Contact person: E.I. Matkevich, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Purpose: To assess the outcomes and implications of modifying SWAN protocol parameters on a 3 Tesla MRI for midbrain structure imaging in patients to detect signs of Parkinson’s disease.
Material and methods: The study was conducted on 22 patients of both genders, ranging in age from 30 to 77 years. Protocols for the standard MRI brain examination and its two variations in the SWAN program, which involved reducing the slice thickness, were analyzed. Key parameters for the visualization of midbrain structures were identified, and subsequently evaluated by expert radiologists.
Results: Parameters within the SWAN protocol for MRI scanning were identified, the modification of which enhances the clarity of nigrosome-1 visualization. It was established that thin-slice modifications of the brain scanning protocols (slice thicknesses of 1.2 and 2 mm) reveal early, diagnostically significant features of nigrosome-1 for Parkinson’s disease 3.4 to 4.1 times more frequently than the standard survey protocol with a slice thickness of 4 mm.
Conclusion: The significance of selecting appropriate MRI protocol parameters for studying midbrain structures to enhance the visualization effectiveness of nigrosome-1 has been confirmed. Employing the SWAN sequence on a 3 Tesla MRI scanner with a slice thickness of 2 mm or less in a neurological department setting during routine Parkinson’s disease examinations achieves superior imaging results compared to conventional survey MRI protocols with a 4 mm slice thickness. This approach demonstrates high inter-rater reliability and aligns with European recommendations for neuroimaging.
Keywords: radiation diagnostics, 3 Tesla MRI, substantia nigra, Parkinson’s disease, nigrosome-1, inter-rater agreement
For citation: Matkevich EI, Ladik ЕА, Bril EV, Zimnyakova OS, Bryukhov VV. Assessment of Midbrain Structure Visualization with Modified 3 Tesla MRI Protocols for Enhanced Parkinson’s Disease Diagnosis. Medical Radiology and Radiation Safety. 2024;69(4):71–76. (In Russian). DOI:10.33266/1024-6177-2024-69-4-71-76
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.03.2024. Accepted for publication: 25.04.2024.