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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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Medical Radiology and Radiation Safety. 2026. Vol. 71. № 4
DOI:10.33266/1024-6177-2026-71-4-92-97
D.E. Kalinkin1, 2, I.V. Milto1, 2, L.V. Smagliy1, 2, G.V. Gorina1, O.V. Litvinova1, Y.A. Samoilova3, V.А. Avkhimenko3, A.R. Takhauov1, L.R. Takhauova1, 2, R.M. Takhauov1, 2
ANALYSIS OF CANCER INCIDENCE AND MORTALITY RATES OF STAFF AT PLUTONIUM PRODUCTION OF SIBERIAN CHEMICAL PLANT
1 Seversk Biophysical Research Center, Seversk, Russia
2 Siberian State Medical University, Tomsk, Russia
3 Siberian Federal Scientific Clinical Center, Seversk, Russia
Contact person: L.V. Smagliy, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To analyze the oncological morbidity and mortality of the personnel of the plutonium production of the Siberian Chemical Plant.
Material and methods: An assessment of the indicators and standardized relative risk of oncological morbidity and mortality of the personnel of the plutonium production of the Siberian Chemical Plant was performed. Cases of malignant neoplasms and deaths due to them in the period 1950–2020 were analyzed for the personnel hired in the period 1950–2015.
Results: In the structure of oncological morbidity and mortality among plutonium production personnel in the period 1950–2020, malignant neoplasms of the digestive organs, respiratory system, urinary tract, genital organs, and mammary gland (in women) were the leading ones. Among the female personnel of the study group, the risks of developing malignant neoplasms with the corresponding total dose of external radiation (mSv) were statistically significantly increased for the digestive organs (> 0 mSv, > 20–50 mSv), respiratory system (> 0 mSv, > 0–20 mSv), skin (> 0 mSv), mammary gland (> 0 mSv, > 20–50 mSv), genitourinary organs (> 0 mSv), as well as malignant neoplasms of all localizations combined (> 0 mSv, > 20–50 mSv). In male personnel, the risk of death due to malignant neoplasms was significantly increased in the respiratory system (> 150–200 mSv and > 300–500 mSv), skin (> 20–50 mSv), and urinary tract
(> 20–50 mSv).
Male personnel in the study group also had a statistically significantly increased risk of death due to malignant neoplasms (with a corresponding total external radiation dose, mSv) of the digestive system (> 100–150 mSv and > 150–200 mSv), respiratory system (> 300–500 mSv), urinary tract (> 0 mSv, > 20–50 mSv), and genitals (> 0 mSv and > 300–500 mSv). Among female personnel – digestive organs (> 0 mSv, > 20–50 mSv), respiration (> 0 mSv, > 0–20 mSv), mammary glands (> 0 mSv, > 20–50 mSv), genital organs (> 0 mSv) and all localizations combined (> 0 mSv, > 20–50 mSv).
Conclusion: Male personnel are characterized by an increased risk of developing malignant neoplasms at doses above 150 mSv (for the respiratory system) and mortality due to malignant neoplasms at doses above 300 mSv (for the respiratory system) and at doses above 150 mSv (for the digestive system). For all other identified malignant neoplasm sites in men, as well as in women, the increased risks of morbidity and mortality are predominantly in the range of up to 50 mSv.
Keywords: personnel, plutonium production, new types of nuclear fuel, malignant neoplasms, morbidity, mortality
For citation: Kalinkin DE, Milto IV, Smagliy LV, Gorina GV, Litvinova OV, Samoilova YA, Avkhimenko VА, Takhauov AR, Takhauova LR, Takhauov RM. Analysis of Cancer Incidence and Mortality Rates of Staff at Plutonium Production of Siberian Chemical Plant. Medical Radiology and Radiation Safety. 2026;71(4):92–97. DOI:10.33266/1024-6177-2026-71-4-92-97
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PDF (RUS) Full-text article (in Russian)
Conflict of interest.The authors declare no conflict of interest.
Financing. The study was carried out as part of the Federal Target Program “Ensuring Nuclear and Radiation Safety for 2016-2020 and for the period up to 2035”.
Contribution. Research concept and design: Kalinkin D.E., Avkhimenko V.A., Takhaouov R.M.; data collection: Samoilova Yu.A., Gorina G.V., Litvinova O.V., Takhaouov A.R., Takhaouova L.R.; analysis and interpretation of results: Kalinkin D.E., Smagliy L.V.; literature review: Smagliy L.V.; manuscript preparation: Kalinkin D.E., Milto I.V. All authors reviewed the results and approved the final version of the manuscript.
Article received: 20.03.2026. Accepted for publication: 25.04.2026.