JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 4. P. 76-82
MEDICAL PRACTICE ISSUE
A.N. Bashkov1, Z.V. Sheykh2, E.A. Ionova1, S.A. Mirzoyants1, N.S. Drebushevskiy1, O.O. Grigor’eva1, A.P. Dunaev1
Unique Case of Giant Exophityc Solitary Liver Metastasis of Neuroendocrine Cancer of Small and Large Intestine
1. A.I. Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. S.P. Botkin City clinical hospital Moscow, Russia.
ABSTRACT
Purpose: To present a rare case of a giant solitary metastasis of the liver with exophytic growth pattern in a patient with neuroendocrine cancer of small intestine and colon, to demonstrate coordinated work of radiology department.
Material and methods: Computer tomography with bolus intravenous administration of 100 ml of contrast agent Ultravist-370 on multislice CT Aquilion 64; whole body scintigraphy on SPECT Philips with intravenous administration of 218.0 MBq 111In-octreotide.
Results: Яmputer tomography revealed a mass in the ileocecal region, which had features of carcinoid, and also a large exophytic solid mass in the left lobe of the liver observed since year 2011. The mass in the liver was solitary, with exophytic growth and heterogeneous structure, much more than the mass in the ileocecal region, maximal accumulate of the contrast agent at the venous phase; thus we thougth of the differential diagnosis between primary tumor and liver metastasis. It was recommended to perform 111In-octreotide SPECT in connection with suspected neuroendocrine cancer. The study has confirmed neuroendocrine nature of masses in the ileocecal region and liver, as well as the accumulation of a specific agent in the sigmoid colon, where was a colonoscopy found polyps. The histopathological study after surgery confirmed neuroendocrine cancer of the small and large intestine with liver metastasis.
Conclusion: 1. A rare case of a giant solitary metastasis of the liver with exophytic growth pattern in a patient with neuroendocrin cancer of small intestine and colon was presented. 2. Data from computer tomography and single photon emission tomography allow to make correct diagnosis at the stage of preoperative examination, despite the atypical signs of the solid mass in the liver.
Key words: neuroendocrine cancer, carcinoid, multidetector spiral computed tomography, single photon emission computed tomography, a solitary exophytic metastasis
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For citation: Bashkov AN, Sheykh ZV, Ionova EA, Mirzoyants SA, Drebushevskiy NS, Grigor'eva OO, Dunaev AP. Unique Case of Giant Exophityc Solitary Liver Metastasis of Neuroendocrine Cancer of Small and Large Intestine. 2014;61(4):76-82. Russian.
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