Medical Radiology and Radiation Safety. 2015. Vol. 60. No. 6. P. 54-59

DISCUSSION

V.A. Lisin^1,2

Some Approaches to the Definition of the Concept of “Radiotherapy Interval” in Radiation Therapy for Cancer<

1. Tomsk Cancer Research Institute, Tomsk, Russia; 2. National Research Tomsk Polytechnic University, Tomsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To analyze the existing approaches to the definition of radiotherapy interval and to consider a more precise quantification of this concept.

Material and methods: Superficial tumors treated with X-rays and fast monoenergetic electrons were used as an example of estimation of a new approach to radiotherapy interval. The characteristics of the dose distributions for X-rays and fast monoenergetic electron beams generated by irradiating the superficial tumors were studied. Dependence of the radiotherapy interval on tumor size for X-rays and fast monoenergetic electron beam was determined by the calculation method. The algorithm for calculation corresponded to the new definition of radiotherapy interval.

Results: A new approach to the definition of radiotherapy interval removes uncertainty and contradictions that existed in the previous definition.

Key words: radiation therapy, radiotherapy interval, X-ray irradiation, fast electrons, dose distribution

REFERENCES

1. Lindenbraten L.D., Lyass F.M. Meditsinskaya radiologiya. Moscow: Meditsina. 1979. 390 p.
2. Yarmonenko S.P. Radiobiologiya cheloveka i zhivotnykh. Moscow: Vysshaya shkola. 1984. 375 p.
3. Lisin V.A., Musabaeva L.I. Kolichestvennaya otsenka luchevykh reaktsii opukholei s uchetom ikh radiobiologicheskikh parametrov. Med. radiologiya. 1983. Vol. 28. No. 12. P. 30-34.
4. Lisin V.A. Teoreticheskaya otsenka effektivnosti fraktsionirovannogo oblucheniya zlokachestvennykh opukholei bystrymi neitronami. Med. radiologiya. 1986. Vol. 31. No. 10. P. 13-18.
5. Lisin V.A. Sposob optimizatsii fraktsionirovaniya dozy v luchevoi terapii zlokachestvennykh opukholei v ramkakh kontseptsii Ellisa. Med. radiologiya. 1984. Vol. 29. No. 12. P. 83-87.
6. Ivanov V.I., Lystsov V.N. Osnovy mikrodozimetrii. Moscow: Atomizdat. 1979. 190 p.
7. Pavlov A.S., Fadeeva M. A., Karyakina N. F. et al. Lineino-kvadratichnaya model' v raschetakh izoeffektivnykh doz, v otsenke protivoopukholevogo effekta i luchevykh oslozhnenii pri luchevoi terapii zlokachestvennykh opukholei. Posobie dlya vrachei. Moscow. 2005. 67 p.
8. Lisin V.A. Otsenka predel'nodopustimoi odnokratnoi dozy pri intraoperatsionnoi luchevoi terapii. Med. fizika. 2006. No. 4. P. 18-23.
9. Calvo F.A., Meirino R.M., Orecchia R. Intraoperatsionnaya luchevaya terapiya: obosnovanie metoda, tekhnicheskie aspekty, rezul'taty klinicheskogo primeneniya. Onkokhirurgiya. 2010. Vol. 2. No. 3. P. 73-82.
10. Fotina I.E. Distantsionnaya radioterapiya. Tomsk: Publ. Tomskogo politekh. un-ta. 2010. 103 p.
11. Yarmonenko S.P., Vainson A.A. Radiobiologiya cheloveka i zhivotnykh. Moscow: Vysshaya shkola. 2004. 510 p.
12. Podlyashuk E.L., Ustinova V.F., Frolova A.V. Luchevaya terapiya na korotkodistantsionnom apparate. Metod. rekomendatsii. Moscow. 1986. 16 p.
13. Emmanuel' N.M., Kavetskii R.E., Tarusov B.N., Sidorik E.P. Biofizika raka. Kiev. 1976. 293 p.
14. Kholin V.V. Radiobiologicheskie osnovy luchevoi terapii zlokachestvennykh opukholei. Leningrad. 1979. 223 p.
15. Ivanov V.K. Matematicheskoe modelirovanie i optimizatsiya luchevoi terapii opukholei. Moscow: Energoizdat. 1986. 145 p.
16. Musabaeva L.I., Lisin V.A., Polishchuk P.F., Chakhlov V.L. Malogabaritnyi betatron dlya elektronnoi terapii poverkhnostnykh opukholei i ego aprobatsiya. Med. radiologiya. 1987. Vol. 32. No. 12. P. 43-47.
17. Uskoriteli elektronov dlya luchevoi terapii. Gosudarstvennyi standart Soyuza SSR, GOST 4.490-89. Gosudarstvennyi Komitet SSSR po standartam. Moscow. 1989.
18. Lisin V.A. Ustroistvo formirovaniya polei elektronnogo izlucheniya, Avtorskoe svidetel'stvo 1290938 ot 15 oktyabrya 1986 g.

For citation: Lisin VA. Some Approaches to the Definition of the Concept of "Radiotherapy Interval" in Radiation Therapy for Cancer. Medical Radiology and Radiation Safety. 2015;60(6):54-9. Russian.

PDF (RUS) Full-text article (in Russian)