Medical Radiology and Radiation Safety. 2014. Vol. 59. No. 5. P. 14-22


N.A. Metlyaeva

Adverse Prognosis of Multifocal Atherosclerosis of Patient, who Transferred Acute Radiation Disease I Degree of Severity

Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


Purpose: Assessment of psychophysiological adaptation of patient B.A.I. with the heavy psychosomatic and all-somatic cardiovascular and cerebrovascular pathology, transferred an acute radiation disease (ARS) of I degree, from the general evenly gamma-beta radiation according to datas features of his individual mental adaptation and the periods of a staginess of mental adaptation.

Material and methods: B.A.I., 1940 year of birth was suffered ARS I degree of severity from uniform gamma-beta radiation. The total dose to the body, according to electro-paramagnetic resonance (EPR) of tooth enamel from 2001, was 0.77 ± 0.25 Gy, on neutrophil — 1,2 Gy, in the culture of cells — 0,7 Gy For 25 years was examined and treated about the acute and long-term effects of ARS I degree of severity and severe progressive cardiovascular and cerebrovascular pathology. Thus, at B.A.I. in dynamics started being formed and progress, the so-called, multifocal atherosclerosis (MFA).

Results: B.A.I. during the first inspection 16.05.1986 and at supervision within 25 years in dynamics (2001, 2002, 2009, 2010) the aspiration to look in favorable light was a leading resistant tendency when testing, showing in answers strict observance even insignificant rules and social norms (L 71.6 scale), subdepressive and disturbing-depressive tendencies (scale 2D 71.2, 9Ma 50.0 T-points, F1 5.1–7.7–8.1 walls). Registration of B.A.I. of the changes overstepping the bounds of population norm, in the form of an affective rigidity (scale of 6Pa 71.0), psychasthenia (a scale of 7Pt 71.8) and original thinking (scale of 8Sch 68.8), along with the indicators of characterizing a neurologic triad (scales 1Hs, 2D, 3Hy), indicate violation not only neurologic, but also psychological adaptation, subdepressive and disturbing and depressive tendencies (scale 2D 71.2, 9Ma 50.0 T-points, F1 5.1–7.7–8.1 walls), caused by weight of all-somatic and psychosomatic pathology.

Conclusions: The subdepressive and disturbing-depressive syndrome in B.A.I. was independent risk factor of development of multifocal atherosclerosis; Features of development of all-somatic and psychosomatic pathology in B.A.I. are based on a combination of genetic prerequisites, environment influences (the stress caused by accident on the ChNPP) and social factors, influencing on him during a course of life, especially during early socialization. Thus at development of psychosomatic frustration the combination of feature of the mental reaction connected with the personal characteristic and special relationship between mental (stress) and physiological (somatic) by aspects of reaction which led to metabolism violation, to aging, decrease in adaptation opportunities of an organism and development age — dependent pathology took place.

Key words: acute radiation disease, ionizing radiation, adaptation, atherosclerosis, hypertensive disease, ischemic heart disease, cerebrovascular arteriosclerosis, obliterating endoangiitis