Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 85–90
Cancer Registry of Population in the City Ozyorsk:
Structure of Malignant Neoplasms First Diagnosed in Period From 1948 to 2016
P.V. Okatenko1, E.P. Fomin2, E.V. Denisova1, I.S. Kuznetsova1, M.E. Sokolnikov1, N.A. Koshurnikova1
1 Southern Urals Biophysics Institute FMBA, Ozyorsk, Russia
2 Clinical Hospital №71 FMBA, Ozyorsk, Russia
Contact person: Pavel Viktorovich Okatenko: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: The analysis of the structure of malignant neoplasms (MN) incidence among the population in the city Ozyorsk, located near Mayak Production Association, based on the information from the territorial cancer registry.
Materials and methods: There were 14681 first diagnosed cases of malignant neoplasms at the period from 1948 to 2016 in the territorial cancer registry of Ozyorsk. The diagnoses were verified by all available medical documents.
The structure of MN incidence, vital status of diseased people, age in a year of diagnostics, rank distribution of the basic localizations were studied.
Results: For 70 years period of follow-up there were 7676 cases from 14681 of MN incidence cases during the last 17 years (from 2000 to 2017) – as much as for the previous 51 years of follow-up from 1948 to 1999 (7005 cases). In the MN structure solid cancer constitutes 94.5 %, hemoblastoses – 5.5 %. As at December 31, 2016 23.3 % of the diseased people were alive, 75.2 % died from all causes, 1.5 % lost to follow-up. The cause of 80,6 % deaths was MN. Age in the year of diagnostics constitutes 61,7 years. 75.8 % diagnoses have morphological confirmation. During the entire period of follow-up first three places belong to lung cancer, gastric cancer and prostate cancer for males; breast cancer, gastric cancer and colon cancer for females in the MN structure.
Conclusions: During the period from 1948 to 2016 the growth of the first diagnosed MN cases among the population of Ozyorsk was a result of the population doubling and a fourfold increase of the citizens over the age of 50. Developed and supported cancer registry allows to analyze and partially control oncological situation in the closed cities of Rosatom.
Key words: cancer-registry, Mayak PA, Ozyorsk, population, malignant neoplasm
For citation: Okatenko PV, Fomin EP, Denisova EV, Kuznetsova IS, Sokolnikov ME, Koshurnikova NA. Cancer Registry of Population in the City Ozyorsk: Structure of Malignant Neoplasms First Diagnosed in Period From 1948 to 2016. Medical Radiology and Radiation Safety. 2021;66(5):85-90.
DOI: 10.12737/1024-6177-2021-66-5-85-90
References
1. A Review of Human Carcinogens. Part D: Radiation. Lyon, France, IARC, 2012. 363 p.
2. Ed. Kiselev M.F., Shandala N.K. ICRP Publication 103. Moscow, Alana Publ., 2009. 344 p. (In Russ.).
3. Vazhenin A.V., Domozhirova A.S., Aksenova I.A., et al. Epidemiological Peculiarities of the Oncological Situation and Health Status Indicators of the Oncological Care Among the Population of Chelyabinsk Region in 2018. Chelyabinsk Publ., 2018. 60 p. (In Russ.).
4. Cancer Registration: Principles and Methods. Lyon, France, IARC, 1991. 169 p.
5. Zielinski J.M., Shilnikova N.S., Krewski D. Canadian National Dose Registry of Radiation Workers: Overview of Research from 1951 through 2007. Int. J. Occup. Med. Environ Health. 2008;21;4:269-75.
6. Haylock R.G.E., Gillies M., Hunter N., et al. Cancer Mortality and Incidence Following External Occupational Radiation Exposure: an Update of the 3rd Analysis of the UK National Registry for Radiation Workers. British Journal of Cancer. 2018;119:631–637.
7. Hunter N., Harrison J.D., Kuznetsova I.S., Labutina E.V. Solid Cancer Incidence other than Lung, Liver and Bone in Mayak Workers: 1948-2004. Br. J. Cancer. 2013;109;7:1989-1996.
8. Labutina E.V., Kuznetsova I.S., Hunter N., et al. Radiation Risk of Malignant Neoplasms in Organs of Main Deposition for Plutonium in the Cohort of Mayak Workers with Regard to Histological Types. Health Phys. 2013;105;2:165-76.
9. Kuznetsova I.S., Labutina E.V., Hunter N. Radiation Risks of Leukemia, Lymphoma and Multiple Myeloma Incidence in the Mayak Cohort: 1948-2004. PLoS ONE. 2016;11;9:1-14.
10. Novoselov V.N., Nosach Yu.F., Entyakov B.N. Atomic Heart of Russia. Chelyabinsk, Avtograf Publ., 2014. 528 p. (In Russ.).
11. Fomin E.P., Okatenko P.V., Koshurnikova N.A. Malignant Neoplasms Incidence among Ozersk Population During the Period 1948-2005. Medical Radiology and Radiation Safety. 2007;52;6:29-34 (In Russ.).
12. Tretyakov F.D., Romanov S.A., Prishchepova M.S., Ryzhov V.P. Demographic Situation in the City Ozersk. Ozersk Publ., 2007. 32 p. (In Russ.).
13. Malignant Neoplasms in Russia. http://www.oncology.ru/service/statistics/malignant_tumors/ (In Russ.).
14. Merkov A.M., Polyakov L.E. Sanitary Statistics. Moscow, Meditcine Publ., 1974. 384 p. (In Russ.).
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 23.12.2020.
Accepted for publication: 20.01.2021.