Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 81–92

Possibilities of Local Microwave Hyperthermia in Oncology

O.K. Kurpeshev

Siberian Scientific Research Institute of Hyperthermia, Novosibirsk, Russia.

Contact person: Orazakhmet Kerimbaevich Kurpeshev, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

CONTENTS

The review analyzes the features of the interaction of electromagnetic (EM) energy with various tissues and the temperature distribution in model, experimental and clinical studies from emitters for external and intracavitary microwave hyperthermia (MWHT). The effect of MWHT on the antitumor efficacy of radiation (RT) and / or chemotherapy (CT), as well as toxic effects on normal tissues, was studied. Based on the literature data and our own experience, some approaches to the treatment of cancer patients have been identified. The general principles of the method, the design features of the applicators and their role in creating a hyperthermic regime in tumors of superficial and subsurface localization are also considered. The development of methods for thermometric control and supply of the EM field, allowing relatively uniform heating of tumors, as well as the determination of the minimum effective thermal doses, remains a priority area of research both in MW and other hyperthermia methods.

Based on the literature data and our own experience, some approaches to the treatment of cancer patients have been identified.

Keywords: hyperthermia, microwave radiation, radiation therapy, chemotherapy, thermoradiotherapy,  thermochemoradiation therapy

For citation: Kurpeshev OK. Possibilities of Local Microwave Hyperthermia in Oncology. Medical Radiology and Radiation Safety. 2021;66(6):81–92.

DOI: 10.12737/1024-6177-2021-66-6-81-92

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Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. The article was prepared by one author.

Article received: 18.09.2021. 

Accepted for publication: 22.10.2021.