Медицинская радиология и радиационная безопасность. 2022. Том 67. № 1

А.Р. Геворков, А.В. Бойко, А.Д. Каприн

СТЕРЕОТАКСИЧЕСКАЯ ЛУЧЕВАЯ ТЕРАПИЯ
БОЛЬНЫХ ОПУХОЛЯМИ ГОЛОВЫ И ШЕИ.
СОВРЕМЕННОЕ СОСТОЯНИЕ ПРОБЛЕМЫ

Национальный медицинский исследовательский центр радиологии Минздрава России, МНИОИ им. П.А.Герцена - филиал НМИЦ радиологии Минздрава России, Москва

Контактное лицо: Геворков Артем Рубенович: This email address is being protected from spambots. You need JavaScript enabled to view it.  

РЕФЕРАТ

Данная публикация представляет собой обзор сегодняшнего состояния проблемы применения стереотаксической лучевой терапии (SBRT) при лечении больных опухолями головы и шеи (ОГШ). Нами проанализированы современные тендеции в ведении пациентов, а также представлены особенности радиобиологии и основные принципы лучевого лечения новообразований вышеуказанной локализации. Отдельное внимание уделено показаниям к проведению стереотаксической лучевой терапии, схемам фракционирования и планирования облучения. Подробно изложен накопленный опыт лучевого лечения с применением SBRT больных первичными ОГШ, в том числе в качестве метода дополнительного прицельного облучения (буста), а также в рамках повторной лучевой терапии при рецидивах. Представлены результаты реализации SBRT различными авторами как в качестве самостоятельной опции, так и в сочетании с лекарственной терапией. В сводной форме с уточняющими комментариями описана эффективность и переносимость облучения. Подробно приведен профиль токсичности лучевой терапии с указанием ключевых факторов риска развития осложнений.

Ключевые слова: опухоли головы и шеи, стереотаксическая лучевая терапия, SBRT

Для цитирования: Геворков А.Р., Бойко., А.В., Каприн А.Д. Стереотаксическая лучевая терапия (SBRT) больных опухолями головы и шеи. Современное состояние проблемы // Медицинская радиология и радиационная безопасность. 2022. Т. 67. № 1. С. 65–76.

DOI: 10.12737/1024-6177-2022-67-1-65-76

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Поступила: 17.07.2021.

Принята к публикации: 05.09.2021.