Medical Radiology and Radiation Safety. 2022. Vol. 67. № 3
A.V. Ozerskaya1, 2, S.Y. Lipaikin2, K.V. Belugin2,
N.A. Tokarev2, N.G. Chanchikova2, M.S. Larkina3, 4,
E.V. Podrezova3, M.V. Belousov3, 4, M.S. Yusubov1, 3, 4
Radiofluorination Methods: Historical Overview and Current State
1Tomsk Polytechnic University, Tomsk, Russia
2Siberian Research Clinical center, Krasnoyarsk, Russia
3Research Centrum for Oncotheranostics, Tomsk Polytechnic University, Tomsk, Russia
4Siberian State Medical University, Tomsk, Russia
Contact person: A.V. Ozerskaya, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
CONTENTS
1. Introduction
2. Radiofluorination methods for obtaining fluorine-18 radiopharmaceuticals
3. Electrophilic radiofluorination
4. Nucleophilic radiofluorination
5. Alternative radiofluorination methods
6. Conclusion
7. References
Keywords: radiopharmaceuticals, radiofluorination, fluorine-18, electrophilic reactions, nucleophilic reactions, chelation
For citation: Ozerskaya AV, Belugin KV, Lipaikin SY, Tokarev NA, Chanchikova NG, Larkina MS, Podrezova EV, Belousov MV, Yusubov MS. Radiofluorination Methods: Historical Overview and Current State. Medical Radiology and Radiation Safety. 2022;67(3):59–66. (In Russian). DOI:10.33266/1024-6177-2022-67-3-59-66
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study was funded by the Ministry of Science and Higher Education of the Russian Federation (075-15-2019-1925).
Contribution. Article was prepared with equal participation of the authors.
Article received: 17.01.2022. Accepted for publication: 15.03.2022.