Medical Radiology and Radiation Safety. 2022. Vol. 67. № 6


S.N. Prokhorov1, N.V. Kochergina1,2, A.D. Ryzhkov1,2,A.S. Krylov1, A.B. Bludov1

Comparison of Bone Scan, X-Ray, Spect/Ct and Mri in the Diagnosis
of Bone Metastases in Solid Tumors

1 N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

2 Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Contact person: Sergei Nikolaevich Prokhorov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.



Purpose: Comparison of the diagnostic performance of osteoscintigraphy (OSG), X-Ray, the presence of OSG and X-ray, SPECT/CT and a combination of MRI sequences in metastatic lesions of the bones of the skeleton.

Material and methods: The study included 24 patients with bone metastases. The above research methods were used. 

Results: The sensitivity of X-ray, Bone scan, X-ray combined with bone scan, SPECT/CT, T1+DWI, T1+STIR+DWI, T1+T2+STIR+DWI, T1+T2+STIR was 10, 30, 24, 31, 99, 99, 99, 95 % respectively, specificity – 37, 12, 59, 74, 87, 87, 87, 71 % respectively. According to the results of pairwise comparison of true-positive results in groups according to the Wilcoxon test: X-ray < OSG = X-ray + OSG = SPECT / CT < MRI + DWI > MRI.

Conclusion: It follows from the results that the choice of diagnostic method for suspected bone metastases should be determined by the clinical context. MRI will help detect bone metastases at earlier stages of development, and the use of other diagnostic methods included in the study should be accompanied by an understanding of the limitations that are imposed in their use.

Keywords: bone metastases, SPECT/CT, Skeletal scintigraphy, X-ray, MRI, comparison study

For citation: Prokhorov SN, Kochergina NV, Ryzhkov AD,Krylov AS, Bludov AB. Comparison of Bone Scan, X-Ray, Spect/Ct and Mri in the Diagnosis of Bone Metastases in Solid Tumors. Medical Radiology and Radiation Safety. 2022;67(6):74–78. (In Russian). DOI:10.33266/1024-6177-2022-67-6-74-78 



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Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.07.2022. Accepted for publication: 25.09.2022.