Medical Radiology and Radiation Safety. 2023. Vol. 68. № 2

DOI: 10.33266/1024-6177-2023-68-2-29-34

A.F. Bobrov1, T.M. Novikova2, V.I. Sedin1, L.I. Fortunatova

System Criteria for Differential Express Diagnostics of Prenosological Disorders of Occupational Health of Employees
at Nuclear Power Facilities 

1A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia

2Central Medical and Sanitary Unit No. 91, Lesnoy, Russia

Contact person: A.F. Bobrov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.



Purpose: Development of complex criteria of differential express-diagnostics of pre-dosological disorders of occupational health of employees of nuclear facilities.

Material and methods: The study object was male workers of the main production facilities of the Electrohimpribor Combine undergoing periodic medical examinations and psychophysiological examinations. The state of health was assessed according to the employee’s belonging to the dispensary observation group in accordance with Order No. 404n of the Ministry of Health of the Russian Federation of April 27, 2021. The psychophysiological state was assessed using a hardware-software complex for group psychophysiological examination APK PFS-CONTROL. Additional testing techniques included assessment of vibraimage parameters, evaluated using computer programs HealthTest and VibraMI, developed in ELSIS (St. Petersburg). Totally 943 man-surveys were carried out with different combination of testing methods. The average age of the workers was (42.0 ± 1.7) years, total work experience was (23 ± 1.3) years, and work experience in the specialty was (13.0 ± 1.8) years.

Results: As a criteria of prenosological health disorders we used the characteristics of the worker’s adaptation to the factors of life activity. Adaptation disorders are evaluated according to three specific criteria: 1) assessment of the functional state of the cardiovascular system according to HRV data; 2) rapid assessment of the psychophysiological state according to vibraimage parameters; 3) assessment of personal and special abilities according to multiple intelligence assessment. For each of the criteria a “traffic light” of states and decisive rules of their formalized identification were developed. Characteristics of unfavorable states are given. Complex express-diagnostics of pre-dosological disorders of occupational health is carried out using integral index, which is a weighted sum of private “traffic light” indexes with a ball score. The formalized express-diagnostics of premalignant disorders is carried out using linear discriminant functions with an average recognition accuracy of 96.4 % or a probabilistic nomogram, which allows to graphically estimate the risk level of health disorders.

Conclusion: Improvement of medical-psychophysiological support of employees of nuclear facilities is connected with introduction of methods and criteria of differential express-diagnosis of prenosological disorders of health. The developed criteria of express-diagnostics of pre-dosological disorders of occupational health expand the existing methodological and criteria base of periodic medical examinations of nuclear industry workers, strengthen their preventive orientation with the purpose of timely application of medical, psychophysiological, organizational and other measures on preservation and maintenance of occupational health of personnel.

Keywords: nuclear industry workers, prenosological conditions, rapid diagnostics, vibraimage technology, multiple intelligence, cardiovascular system, activity index of regulatory systems

For citation: Bobrov AF, Novikova TM, Sedin VI, Fortunatova LI.System Criteria for Differential Express Diagnostics of Prenosological Disorders of Occupational Health of Employees at Nuclear Power Facilities. Medical Radiology and Radiation Safety. 2023;68(2):
29–34. (In Russian). DOI: 10.33266/1024-6177-2023-68-2-29-34



1. Bayevskiy R.M. Prognozirovaniye Sostoyaniy na Grani Normy i Patologii = Prediction of Condition on the Brink of Norm and Pathology. Moscow, Meditsine Publ., 1979. 298 p. (In Russ.).

2. Bayevskiy R.M. Otsenka Adaptatsionnykh Vozmozhnostey Organizma i Risk Razvitiya Zabolevaniy = Assessment of Adaptive Capacity of the Organism and the Risk of Diseases. Moscow, Meditsine Publ., 1997. P. 104 (In Russ.).

3. Kaznacheyev V.P. Donozologicheskaya Diagnostika v Praktike Massovykh Obsledovaniy Naseleniya = Prenosological Diagnostics in Practice of Mass Screening of the Population. / Ed. Kaznacheyev V.P., Bayevskiy R.M., Berseneva A.P. Leningrad, Meditsina Publ., 1980. 225 p. (In Russ.).

4. Minkin V.A. Vibroizobrazheniye, Kibernetika i Emotsii = Vibroimage, Cybernetics and Emotions. St. Petersburg, Renome Publ., 2020. 164 p. DOI: 10.25696/ELSYS.B.RU.VCE.2020 (In Russ.).

5. Minkin V.A. Vibroizobrazheniye = Vibroimage. St. Petersburg, Renome Publ., 2007. 108 p. DOI: 10.25696/ELSYS.B.RU.VI.2007; ISBN 978-5-98947-074-7(In Russ.).

6. R FMBA of Russia Organization and Conduct of Psychophysiological Examinations of Employees of Organizations Operating Especially Radiation Hazardous and Nuclear Hazardous Industries and Facilities in the Field of Atomic Energy Use, When Employees Undergo Medical Examinations in Medical Organizations of FMBA of Russia. Methodological Recommendations (Approved by FMBA of Russia on 29.12.2015). URL: (Date of Access: 24.03.2022) (In Russ.).

7. Sistema Diagnostiki Psikhofiziologicheskogo Sostoyaniya i Funktsionalnogo Zdorovya Cheloveka = Diagnostic System of Psycho-Physiological State and Functional Health of a Person. Operation Manual. Version: VibraHT. St. Petersburg, Elsis Publ., 2020. URL: http: (Date of Access: 24.03.2022) (In Russ.).

8. Sistema Psikhofiziologicheskogo Profaylinga = Psychophysiological Profiling System. Software, Operation Manual Version: VibraMI10 (VibraMI10). St. Petersburg, Elsis Publ., 2016. URL: (Date of Access: 24.03.2022) (In Russ.).

9. Roracher, G., Inanaga K. Microvibration: Its Biological Function and Clinical and Diagnostic Significance. Verlag Hans Huber Bern Publishers, 1969. 160 p. 

10. Bobrov A.F., Novikova T.M., Proskuryakova N.L., Sedin V.I., Shchelkanova Ye.S., Fortunatova L.I., Kalinina M.Yu. Express-Diagnostics of the Health of Workers of Dangerous Productions. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost = Medical Radiology and Radiation Safety. 2022;67;3:89-93. DOI:10.33266/1024-6177-2022-67-3-89-93 (In Russ.).

11. Gardner, G. Structure of Mind: Theory of Multiple Intelligence. Translated from English. Moscow Publ., 2007. 512 p.

12. Minkin V.A., Nikolayenko Ya.N. Vibroizobrazheniye i Mnozhestvennyy Intellekt = VibraImage and Multiple Intelligence. St. Petersburg, Renome Publ., 2017. 156 p. (In Russ.).

13. Bobrov A.F., Ivanov V.V., Novikova T.M., Kuznetsova L.I., Shcheblanov V.Yu. Express-Evaluation of Psychophysiological Adaptation of Workers of Dangerous Productions on the Characteristics of Multiple Intelligence. Mediko-Biologicheskiye i Sotsialno-Psikhologicheskiye Problemy Bezopasnosti v Chrezvychaynykh Situatsiyakh = Medicо-Biological and Socio-Psychological Problems of Safety in Emergency Situations. 2019;3:74-84. DOI 10.25016/2541-7487-2019-0-3-74-84 (In Russ.)

14. Kim J.-O. Factor, Discriminant and Cluster Analysis. Moscow, Finances and Statistics Publ., 1989. 215 p.



 PDF (RUS) Full-text article (in Russian)

Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.11.2022. Accepted for publication: 25.01.2023.