Medical Radiology and Radiation Safety. 2023. Vol. 68. № 3

DOI: 10.33266/1024-6177-2023-68-3-66-70

S.N. Prokhorov1, A.S. Krylov1, A.V. Kuzin2, A.D. Ryzhkov1, 2,
N.V. Kochergina1, 2, A.I. Pronin1, A.B. Bludov1, S.G. Anikin3

SAPHO Syndrome: Difficulties of Diagnosis in the Clinical Case. Radiology Imaging

1N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

2Russian Medical Academy of Continuous Professional Education, Moscow, Russia

3V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia

Contact person: Sergei Nickolaevich Prokhorov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.



Purpose: Demonstrate the possible manifestations of SAPHO syndrome.

Material and methods: 38-year-old woman with suspected SAPHO syndrome were performed scintigraphy and SPECT/CT for evaluate the localization and abundance of the process.

Results: Osteosclerosis and hyperostosis of the left clavicle, osteosclerosis of the L1 vertebra and other, less pronounced changes, accompanied by active accumulation of the 99mTc-MDP, were revealed.

Conclusion: It is important to remember the specific complex of symptoms of this nosological entity and the possible isolated onset of individual manifestations, which was also observed in our case.

Keywords: SAPHO syndrome, SPECT/CT, bone scan

For citation: Prokhorov SN, Krylov AS, Kuzin AV, Ryzhkov AD, Kochergina NV, Pronin AI, Bludov AB, Anikin SG. SAPHO Syndrome: Difficulties of Diagnosis in the Clinical Case. Radiology Imaging. Medical Radiology and Radiation Safety. 2023;68(3):66–70. (In Russian). DOI: 10.33266/1024-6177-2023-68-3-66-70



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Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.01.2022. Accepted for publication: 25.02.2023.