Medical Radiology and Radiation Safety. 2023. Vol. 68. № 4
DOI: 10.33266/1024-6177-2023-68-4-81-84
A.V. Muravleva, V.E. Goldberg, E.A. Dudnikova, T.L. Kravchuk, R.V. Zelchan,
A.A. Medvedeva, O.D. Bragina, E.I. Simolina, N.O. Popova, V.V. Vysockaja,
V.A. Shatalova, A.N. Rybina, A.V. Goldberg, S.A. Tabakaev, V.I. Chernov
Metabolic 99mTc-1-Thio-D-Glucose SPECT/CT in the Diagnosis
of Brain Metastasis of Genital Diffuse-B-Large Cell Lymphoma (Clinical Case)
Cancer Research Institute, Tomsk National Research Medical Center, Tomsk, Russia
Contact person: A.V. Muravleva, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To demonstrate a rare clinical case of early recurrence of verified primary genital lymphoma and the possibility of 99mTc-1-Thio-D-glucose (99mTc-TG) SPECT/CT using to brain metastasis diagnosis.
Material and methods: A patient with a diagnosis of primary diffuse large B-cell genital lymphoma underwent magnetic resonance imaging (MRI) to assess the extent of the disease. Post-treatment follow-up included 18F-FDG PET/CT. To diagnose brain metastasis, 99mTc-TG SPECT/CT and MRI were performed.
Results: A rare case of early recurrence of diffuse large B-cell lymphoma with a primary local lesion in the genital organs is described. The possibility of modern methods of nuclear medicine in the diagnosis of early recurrence of malignant lymphoma has been demonstrated. 99mTc-TG SPECT/CT and MRI, were useful for visualization of a high metabolic brain tumor at the outpatient stage and recommendation of high-dose therapy according to the scheme MT-R was done.
Conclusion: The article presents a rare clinical case of early recurrence of diffuse large B-cell genital lymphoma. Possibilities of SPECT/CT with 99mTc-TG for visualization of lymphoma metastasis to the brain were demonstrated.
Keywords: diffuse large B-cell genital lymphoma, brain metastasis, single photon emission computed tomography, 99mTc-1-Thio-D-glucose
For citation: Muravleva AV, Goldberg VE, Dudnikova EA, Kravchuk TL, Zelchan RV, Medvedeva AA, Bragina OD, Simolina EI, Popova NO, Vysockaja VV, Shatalova VA, Rybina AN, Goldberg AV, Tabakaev SA, Chernov VI. Metabolic 99mTc-1-Thio-D-Glucose SPECT/CT in the Diagnosis of Brain Metastasis of Genital Diffuse-B-Large Cell Lymphoma (Clinical Case). Medical Radiology and Radiation Safety. 2023;68(4):81–84. (In Russian). DOI:10.33266/1024-6177-2023-68-4-81-84
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.02.2022. Accepted for publication: 27.03.2023.