Medical Radiology and Radiation Safety. 2024. Vol. 69. № 1

DOI:10.33266/1024-6177-2024-69-1-88-91

I.O. Tomashevsky, O.S. Kornikova 

The Impotance of SPECT/CT in Simultaneous Assessment
of Calcinosis of Coronary Arteries, Perfusion and Contractile Function of the Myocardium among Females with Coronary Heart Disease

Central Clinical Hospital RZD-Medicine, Moscow, Russia

Contact person: Igor Ostapovich Tomashevsky, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To study the frequency of calcinosis of coronary arteries and its effect on myocardial perfusion and contractile function among females with coronary heart disease (CHD).

Material and methods: A survey was conducted among 141 females with coronary heart disease (CHD): simultaneous assessment of coronary artery calcinosis, perfusion and contractile function with ^99m Tc-technetril SPECT/CT with ECG-synchronization and X-ray radiation correction, as well as comparison of data with the results of electrocardiography (ECG), echocardiography (ECHO-CG), clinical and biochemical blood tests.

Results: Coronary artery calcinosis was detected in 33 (23 %) females with coronary heart disease (CHD) out of all patients identified: over the age of 55 years (M = 67 years with variations from 58 to 83 years) ‒ in 25 (17.7 %), aged 41‒55 years (M = 50 years with variations from 46 to 54 years) ‒ in 7 (4.6 %), at the age of 25‒40 years ‒ in one female 35 years (0.7 %). The Agatston calcium score interval was set as follows: at the maximum degree > 400 ‒ for 6 females (4.2 % of all surveyed); at 101‒400 ‒ in 9 (6.4 %); at 11‒100 ‒ in 17 (12.0 %); at 1‒10 ‒ in one female (0.7 %); with a minimum degree of 0 ‒ in 108 females (76.7 % of all surveyed). In the presence of maximum degree of calcinosis (> 400 units), a slight significant decrease in perfusion, an increase in ejection fraction and diastole duration was revealed.

Conclusion: The use of combined SPECT/CT with ECG synchronization and CT radiation correction technology in 141 females with coronary artery disease made it possible to identify coronary artery calcinosis in 23 % of patiets.

Keywords: females, coronary heart disease, SPECT/CT, myocardium, calcinosis of coronary arteries, perfusion, contractile function of the myocardium

For citation: Tomashevsky IO, Kornikova OS. The Impotance of SPECT/CT in Simultaneous Assessment of Calcinosis of Coronary Arteries, Perfusion and Contractile Function of the Myocardium among Females with Coronary Heart Disease. Medical Radiology and Radiation Safety. 2024;69(1):88–91. (In Russian). DOI:10.33266/1024-6177-2024-69-1-88-91

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Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. I.O. Tomashevsky took part in the development of the concept, design, theoretical basis, modification of research methods. O. Kornikova took part in the collection and analysis of literary material, statistical data processing, writing and scientific editing of the text.

Article received: 20.10.2023. Accepted for publication: 27.11.2023.