Medical Radiology and Radiation Safety. 2025. Vol. 70. № 2

DOI:10.33266/1024-6177-2025-70-2-81-87

P.V. Sychev¹, Yu.D. Udalov^{1, 2}, E.V. Mayakova¹, Yu.A. Kaidash¹, M.I. Shcherbakov¹, I.A. Baryshnikov¹

Epidemiological Analysis of Thyroid Cancer in the System of FMBA of Russia

¹ Federal Scientific Clinical Center for Medical Radiology and Oncology, Dimitrovgrad, Russia

² A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia

Contact person: Petr Vladimirovich Sychev, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: According to statistical data for 2022, thyroid cancer (TC) is in 3rd place in terms of detection frequency (9.4 %) in people under 30 years of age. At the same time, the frequency of malignant neoplasms (MNT) of the thyroid gland in young women from 0 to 29 years old is 13.6 %, which is more than the frequency of cervical cancer (8.4 %) [1]. According to the register of cancer patients of the Volga Federal District in 2022, the number of patients with cancer of the thyroid gland registered in oncology institutions with a diagnosis of cancer for the first time in their life is 2,231 people. By the end of this year, 20,908 patients had been registered for 5 years or more; mortality averaged 0.5 %.

The above circumstances dictate the need to find ways to improve the results of radioiodine therapy for thyroid cancer based on its timely diagnosis, prevention of secondary resistance and optimization of treatment tactics. This became the prerequisites for the development of a modern tool for epidemiological analysis of the results of the use of radionuclide therapy ¹³¹I in the treatment of thyroid cancer in the FMBA system of Russia and the implementation of applied research work according to the State assignment.

Material and methods: Over the course of a year and a half of research, data on radioiodine therapy for thyroid cancer at the Nuclear Medicine Centers of the Federal Medical and Biological Agency of Russia were studied for more than 900 patients from various regions of the Russian Federation. The necessary medical documentation of these patients was studied, data was generated, subjected to epidemiological analysis and entered into an electronic database.

Results: The study analyzed the criteria that most optimally reflect the patient’s condition upon admission, treatment parameters and indicators of its effectiveness. The result of this work is to optimize treatment parameters, which will allow us to determine a personalized approach to radionuclide therapy with ¹³¹I in the treatment of thyroid cancer.

Keywords: thyroid cancer, epidemiology, radioiodine therapy, ¹³¹I

For citation: Sychev PV, Udalov YuD, Mayakova EV, Kaidash YuA, Shcherbakov MI, Baryshnikov IA. Epidemiological Analysis of Thyroid Cancer in the System of FMBA of Russia. Medical Radiology and Radiation Safety. 2025;70(2):81–87. (In Russian). DOI:10.33266/1024-6177-2025-70-2-81-87

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Conflict of interest. The authors declare no conflict of interest.

Financing. The work was performed within the framework of the state assignment of the FMBA of the Russia registration No. R&D 1022060300090-7-3.2.21.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.12.2024. Accepted for publication: 25.01.2025.