Medical Radiology and Radiation Safety. 2026. Vol. 71. № 2

DOI:10.33266/1024-6177-2026-71-2-53-65

A.N. Koterov1, L.N. Ushenkova1, A.A. Wainson2, O.A. Tikhonova1,
A.S. Kretov1, O.V. Parinov1, A.O. Lebedev1, A.Yu. Bushmanov1

Suicide Risk Among Nuclear Workers: Differences for Male and Female are Inverse to Population-Based Results (Synthetic Study). Report 1. Problem Statement, Search for Sources, and Characteristic of the Sample

1 A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia

2 N.N. Blokhin Russian Cancer Research Center, Moscow, Russia

Contact person: Alexey N. Koterov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

Abstract

Suicide rate is considered an index of social and professional well-being/ill-being. Therefore, studying this index among nuclear workers (NW), a group subordinate to the Federal Medical-Biological Agency of the Russian Federation, is relevant both for image-building purposes and for optimizing psychological support for this category of workers. This two-report cycle (a synthetic study) presents a systematic review, followed by a meta-analysis and pooled analysis, for suicide risk among NW in different countries and gender patterns of this risk (Standardized Mortality Ratio (SMR) compared to the general population).

This Report 1 presents, first, a search methodology for sources in a supported bibliographic database for NW in different countries, including PubMed, Embase, Google Scholar, eLibrary, and the reference lists of identified publications. The primary sample, generated based on the search results for all the specified types, totaled 556 sources (many duplicates), allowing for visual analysis of all of them during subsequent selection.

Second, the stages of processing the resulting sample in preparation for meta- and pooled analyses are described (selection of studies with only SMR indexes, only the most recent chronological publications for the studied cohorts, elimination of outliers in the samples, and assessment of the epidemiological quality of the remaining studies).

None of the four identified USSR/Russian studies (all for the PO ‘Mayak’) were included in the systematic review due to the lack of the necessary risk index. Nevertheless, some qualitative conclusions were reached, according to which, with overexposure to NW from the PO ‘Mayak’ (up to more than 1 and 4 Gy in two studies), an increased risk of suicide was observed; in the absence of high exposure levels, the unweighted risk index was not increased compared to the general population for male. A reverse ‘gender paradox’ was also observed, with the fatal suicide rate among female NW at the PO ‘Mayak’ being higher than among males, while a direct ‘gender paradox’ (a multiple higher suicide rate for males and a multiple higher rate of suicide attempts for females) has been described for the populations of almost all countries since the 19th century.

For foreign NWs, two study samples were created, corresponding to 15 nuclear installations (from five countries; 62% from the USA) for both male NW and female NW (coincidence). Further meta-analyses and pooled analyses of SMR for suicides in foreign NW, as well as a comparison of their risk for male and female cohorts to test for the reverse ‘gender paradox’, will be presented in Report 2.

Keywords: nuclear workers, fatal suicides, systematic review

For citation: Koterov AN, Ushenkova LN, Wainson AA, Tikhonova OA, Kretov AS, Parinov OV, Lebedev AO, Bushmanov AYu. Suicide Risk Among Nuclear Workers: Differences for Male and Female are Inverse to Population-Based Results (Synthetic Study). Report 1. Problem Statement, Search for Sources, and Characteristic of the Sample. Medical Radiology and Radiation Safety. 2026;71(2):53–65. DOI:10.33266/1024-6177-2026-71-2-53-65

 

References

  1. Fukui T., Rahman M., Sekimoto M., Hira K., Maeda K., Morimoto T., et al. Study Design, Statistical Method, and Level of Evidence in Japanese and American Clinical Journals. J. Epidemiol. 2002;12;3:266–270. Doi: 10.2188/Jea.12.266.
  2. Власов В.В. Эпидемиология: Учебное пособие. 2-е изд. М.: ГЭОТАР-Медиа, 2006. 464 с. [Vlasov V.V. Epidemiologiya = Epidemiology. Textbook. 2nd ed. Moscow, GEOTAR-Media Publ., 2006. 464 p. (In Russ.)].
  3. UNSCEAR 2017. Report to the General Assembly, with Scientific Annexes. Annex A. Principles and Criteria for Ensuring the Quality of the Committee’s Reviews of Epidemiological Studies of Radiation Exposure.  United Nations. New York, 2018. P. 17–64.
  4. Jadad A.R., Enkin M.W. Randomized Controlled Trials. Questions, Answers, and Musings. 2nd edition.  Malden, Oxford, Carlton, BMJ Books, 2007.  136 p.
  5. Blettner M., Sauerbrei W., Schlehofer B., Scheuchenpflug T., Friedenreich C. Traditional Reviews, Meta-Analyses and Pooled Analyses in Epidemiology. Int. J. Epidemiol. 1999;28;1:1–9. Doi: 10.1093/Ije/28.1.1.
  6. Friedenreich C.M. Methods for Pooled Analyses of Epidemiologic Studies. Epidemiology. 1993;4;4:295–302. Doi: 10.1097/00001648-199307000-00004.
  7. Bravata D.M., Olkin I. Simple Pooling Versus Combining in Meta-Analysis. Eval. Health Prof. 2001;24;2:218–230. Doi: 10.1177/01632780122034885.
  8. Котеров А.Н., Ушенкова Л.Н., Калинина М.В., Бирюков А.П. Сравнение риска смертности от солидных раков после радиационных инцидентов и профессионального облучения // Медицина труда и промышленная экология. 2021. Т.61. №9. С. 580–587 [Koterov A.N., Ushenkova L.N., Kalinina M.V., Biryukov A.P. Comparison of the Risk of Mortality from Solid Cancers after Radiation Incidents and Occupational Exposure. Meditsina Truda i Promyshlennaya Ekologiya = Russian Journal of Occupational Health and Industrial Ecology. 2021;61;9:580–587 (In Russ.)]. Doi: 10.31089/1026-9428-2021-61-9-580-587.
  9. Sturmberg J.P. Evidence-Based Medicine — not a Panacea for the Problems of a Complex Adaptive World. J. Eval. Clin. Pract. 2019;25;5:706–716. Doi: 10.1111/Jep.13122.
  10. Umbrella Reviews: Evidence Synthesis with Overviews of Reviews and Meta-Epidemiologic Studies. Ed. by G. Biondi-Zoccai. 1st Edition.  Springer International Publishing, Switzerland, 2016.  526 p.
  11. Trinquart L., Dechartres A., Ravaud P. Commentary: Meta-Epidemiology, Meta-Meta-Epidemiology or Network Meta-Epidemiology? Int. J. Epidemiol. 2013;42;4:1131–1133. Doi: 10.1093/Ije/Dyt137.
  12. Котеров А.Н., Ушенкова Л.Н., Буланова Т.М., Богданенко Н.А. Отраслевые библиографические базы данных: перспективы использования в ФМБА России для научной экспертизы при принятии решений. Сообщение 1. Общие вопросы и база данных по медико-биологическим и иным эффектам у работников ядерной индустрии // Медицинская радиология и радиационная безопасность. 2025. Т.70. №2. С. 88–106 [Koterov A.N., Ushenkova L.N., Bulanova T.M., Bogdanenko N.A. Industry Bibliographic Databases: Prospects for Use in the Federal Medical and Biological Agency of Russia for Scientific Expertise in Decision-Making. Report 1. General Issues and a Database on Medical, Biological and other Effects in Workers in the Nuclear Industry. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2025;70;2:88–106 (In Russ.)]. Doi: 10.33266/1024-6177-2025-70-2-88-106.
  13. Котеров А.Н., Ушенкова Л.Н., Буланова Т.М., Богданенко Н.А. Отраслевые библиографические базы данных: перспективы использования в ФМБА России для научной экспертизы при принятии решений. Сообщение 2. База данных по медико-биологическим и иным эффектам у шахтеров урановых рудников // Мед. радиология и радиац. безопасность. 2025. Т.70. № 4. С. 66–76 [Koterov A.N., Ushenkova L.N., Bulanova T.M., Bogdanenko N.A. Industry Bibliographic Databases: Prospects for Use in the Federal Medical and Biological Agency of Russia for Scientific Expertise in Decision-Making. Report 2. Database on Medical, Biological and other Effects in Uranium Miners. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2025;70;4;66-76 (In Russ.)]. Doi: 10.33266/1024-6177-2025-70-4-66-77.
  14. Grint K., Nixon D. The Sociology of Work. 4th Edition.  John Wiley & Sons, 2025.  472 p.
  15. Котеров А.Н., Ушенкова Л.Н., Дибиргаджиев И.Г., Буланова Т.М. Сравнение риска общей смертности для работников ядерной индустрии, шахтеров урановых рудников и других профессий с риском пассивного курения (мета-анализы) // Мед. радиология и радиац. безопасность. 2024. V.69. №5. С. 75–86 [Koterov A.N., Ushenkova L.N., Dibirgadzhiyev I.G., Bulanova T.M. Comparison of the Risk of Overall Mortality for Workers in the Nuclear Industry, Uranium Miners and other Professions with the Risk of Passive Smoking (Meta-Analyses). Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2024;69;5:75–86 (In Russ.)]. Doi: 10.33266/1024-6177-2024-69-5-75-86.
  16. Котеров А.Н., Ушенкова Л.Н., Дибиргаджиев И.Г., Калинина М.В. Смертность от всех причин и от всех раков для работников ядерной индустрии и шахтеров урановых рудников сравнительно с наиболее вредными/опасными профессиями (синтетическое исследование) // Здоровье и окружающая среда: Сб. научн. тр. / Под ред. С.И.Сычика и др.  Гомель: Гомельская прауда, 2024. С. 59–69 [Koterov A.N., Ushenkova L.N., Dibirgadzhiyev I.G., Kalinina M.V. Mortality from all Causes and from all Cancers for Workers in the Nuclear Industry and Uranium Miners Compared with the Most Harmful/Dangerous Professions (Synthetic Study). Collection of Scientific Papers Zdorov’ye i Okruzhayushchaya Sreda = Health and the Environment. Ed. S.I.Sychik, et al. Gomel, Gomel’skaya Prauda Publ., 2024. P. 59–69 (In Russ.)].
  17. Котеров А.Н., Ушенкова Л.Н., Вайнсон А.А., Дибиргаджиев И.Г., Калинина М.В., Бушманов А.Ю. Риск смертности от основных патологий вследствие пассивного курения не достигается подавляющим большинством работников ядерной индустрии всех периодов занятости // Мед. радиология и радиац.безопасность. 2024. Т.69. №3. С. 57–67 [Koterov A.N., Ushenkova L.N., Vaynson A.A., Dibirgadzhiyev I.G., Kalinina M.V., Bushmanov A.Yu. The Risk of Mortality from Major Pathologies Due to Passive Smoking is not Achieved by the Overwhelming Majority of Workers in the Nuclear Industry of All Periods of Employment. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2024;69;3:57–67 (In Russ.)]. Doi: 10.33266/1024-6177-2024-69-3-57-67.
  18. Tsai S.P., Hardy R.J., Wen C.P. The Standardized Mortality Ratio and Life Expectancy. Am. J. Epidemiol. 1992;135;7:824–831. Doi: 10.1093/Oxfordjournals.Aje.A116369.
  19. Котеров А.Н., Ушенкова Л.Н., Калинина М.В., Бирюков А.П. «Эффект здорового работника» по показателям общей смертности и смертности от злокачественных новообразований у персонала предприятий ядерной и химической индустрии: мета-анализы // Мед. радиология и радиац. безопасность. 2023. Т.68. № 4. С. 43–50 [Koterov A.N., Ushenkova L.N., Kalinina M.V., Biryukov A.P. The Healthy Worker Effect in Terms of Overall Mortality and Mortality from Malignant Neoplasms among Personnel of Nuclear and Chemical Industry Enterprises: Meta-Analyses. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2023;68;4:43–50 (In Russ.)] Doi: 10.33266/1024-6177-2023-68-4-43-50.
  20. Cousteaux A.-S., Pan Ke Shon J.-L. Is Ill-Being Gendered? Suicide, Risk for Suicide, Depression and Alcohol Dependence. R. Fanc. Sociol. 2010;51;5:3–40. Doi: 10.3917/Rfs.515.0003.
  21. Гилинский Я.И. Самоубийство как социальный феномен // Социологический журнал. 2011. №2. С. 39–48 [Gilinskiy Ya.I. Suicide as a Social Phenomenon. Sotsiologicheskiy Zhurnal = Sociological Journal. 2011;2:39–48  (In Russ.)].
  22. Landy F., Quick J.C., Kasl S. Work, Stress, and Well-Being. International Journal of Stress Management. 1994;1;1:33–73. Doi: 10.1007/Bf01857282.
  23. Brodsky C.M. Suicide Attributed to Work. Suicide Life Threat Behav. 1977;7;4:216–229. Doi: 10.1111/j.1943-278X.1977.tb00893.x.
  24. Bedeian A.G. Suicide and Occupation: a Review. Journal of Vocational Behavior. 1982;21;2:206–223. Doi: 10.1016/0001-8791(82)90030-6.
  25. Boxer P.A., Burnett C., Swanson N. Suicide and Occupation: a Review of the Literature. J. Occup. Environ. Med. 1995;37;4:442–452. Doi: 10.1097/00043764-199504000-00016.
  26. Samuels S.W. A Moral History of the Evolution of a Caste of Workers. Environ. Health Perspect. 1996;104;5:991–998. Doi: 10.1289/Ehp.96104s5991.
  27. Roberts S.E., Jaremin B., Lloyd K. High-Risk Occupations for Suicide. Psychol. Med. 2013;43;6:1231–1240. Doi: 10.1017/S0033291712002024.
  28. Baumert J., Schneider B., Lukaschek K., Emeny R.T., Meisinger C., Erazo N., et al. Adverse Conditions at the Workplace are Associated with Increased Suicide Risk. J. Psychiatr. Res. 2014;57:90–95. Doi: 10.1016/J.Jpsychires.2014.06.007.
  29. Loerbroks A., Cho S.I., Dollard M.F., Zou J., Fischer J.E., Jiang Y., et al. Associations between Work Stress and Suicidal Ideation: Individual-Participant Data from Six Cross-Sectional Studies. J. Psychosom. Res. 2016;90:62–69. Doi: 10.1016/J.Jpsychores.2016.09.008.
  30. Milner A., Witt K., LaMontagne A.D., Niedhammer I. Psychosocial Job Stressors and Suicidality: a Meta-Analysis and Systematic Review. Occup. Environ. Med. 2018;75;4:245–253. Doi: 10.1136/oemed-2017-104531.
  31. Guseva-Canu I., Bovio N., Mediouni Z., Bochud M., Wild P. Swiss National Cohort (SNC). Suicide Mortality Follow-Up of the Swiss National Cohort (1990–2014): Sex-Specific Risk Estimates by Occupational Socio-Economic Group in Working-Age Population. Soc. Psychiatry Psychiatr. Epidemiol. 2019;54;12:1483–1495. Doi: 10.1007/S00127-019-01728-4.
  32. Kim S.Y., Shin Y.C., Oh K.S., Shin D.W., Lim W.J., Cho S.J., Jeon S.W. Association between Work Stress and Risk of Suicidal Ideation: a Cohort Study among Korean Employees Examining Gender and Age Differences. Scand. J. Work Environ. Health. 2020;46;2:198–208. Doi: 10.5271/Sjweh.3852.
  33. Aberg M., Staats E., Robertson J., Schioler L., Toren K., LaMontagne A.D., et al. Psychosocial Job Stressors and Risk of Suicidal Behavior ‒ an Observational Study among Swedish Men. Scand. J. Work Environ. Health. 2022;48;6:435–445. Doi: 10.5271/sjweh.4039.
  34. Stare J., Boulch D.M. Odds Ratio, Hazard Ratio and Relative Risk. Metodoloski Zvezki. 2016;13;1:59–67. Doi: 10.51936/Uwah2960.
  35. About WONUC [World Council of Nuclear Workers]. Proceedings 1st Internat. Symp. The Effects of Low and Very Low Doses of Ionizing Radiation on Human Health. France, Saint Quentin en Yvelines, 17–18 June 1999. Ed. by WONUC’.  Elsevier Science B.V., 2000.
  36. Shrader-Frechette K. Trading Jobs for Health: Ionizing Radiation, Occupational Ethics, and the Welfare Argument. Sci. Eng. Ethics. 2002;8;2:139–154. Doi: 10.1007/S11948-002-0015-4.
  37. Laurier D., Marsh J.W., Rage E., Tomasek L. Miner Studies and Radiological Protection Against Radon. Ann. ICRP. 2020;49;1:57–67. Doi: 10.1177/0146645320931984.
  38. Varnik P. Suicide in the World. Int. J. Environ. Res. Public Health. 2012;9:760–771. Doi: 10.3390/Ijerph9030760.
  39. Yip P.S., Callanan C., Yuen H.P. Urban/Rural and Gender Differentials in Suicide Rates: East and West. J Affect Disord. 2000;57;1–3:99–106. Doi: 10.1016/S0165-0327(99)00058-0.
  40. Demir M. Gender Differences in Suicide Rates. Forensic Science & Addiction Research. 2018;2;4:161–165. Doi: 10.31031/Fsar.2018.02.000550.
  41. Bommersbach T.J., Rosenheck R.A., Petrakis I.L., Rhee T.G. Why are Women more Likely to Attempt Suicide than Men? Analysis of Lifetime Suicide Attempts among US Adults in a Nationally Representative Sample. J. Affect Disord. 2022;311:157–164. Doi: 10.1016/J.Jad.2022.05.096.
  42. Berardelli I., Rogante E., Sarubbi S., Erbuto D., Cifrodelli M., Concolato C., et al. Is Lethality Different between Males and Females? Clinical and Gender Differences in Inpatient Suicide Attempters.Int. J. Environ. Res. Public Health. 2022;19;20;13309. 8 p. Doi: 10.3390/Ijerph192013309.
  43. Cochrane Handbook for Systematic Reviews of Interventions. 2nd Edition. Ed. by J.P.T. Higgins, T. James, J. Chandler, et al. Cochrane, Willey Blackwell, 2019. 694 p. Doi: 10.1002/9781119536604.
  44. Wilkinson G.S., Trieff N., Graham R., Priore R.L. Study of Mortality among Female Nuclear Weapons Workers. Final Report. Grant Numbers: 1R01 OHO3274, R01/CCR214546, R01/CCR61 2934-01. 2000. 447 p. URL: https://stacks.cdc.gov/view/cdc/217970 (Date of Access 15.12.2025).
  45. Boice J.D. Jr, Cohen S.S., Mumma M.T., Chadda B., Blot W.J. A Cohort Study of Uranium Millers and Miners of Grants, New Mexico, 1979–2005. J. Radiol. Prot. 2008;28;3:303–325. Doi: 10.1088/0952-4746/28/3/002.
  46. OCRC-2015. The Occupational Cancer Research Centre, Cancer Care Ontario. Ontario Uranium Miners Cohort Study Report. Prepared for: The Canadian Nuclear Safety Commission. 2015.  137 p. URL: https://www.occupationalcancer.ca/wp-content/uploads/2023/01/RSP-0308.pdf (Date of Access 15.12.2025).
  47. Kreuzer M., Schnelzer M., Tschense A., Walsh L., Grosche B. Cohort Profile: the German Uranium Miners Cohort Study (WISMUT cohort), 1946–2003. Int. J. Epidemiol. 2010;39;4:980–987. Doi: 10.1093/Ije/Dyp216.
  48. Figgs L.W., Holsinger H., Freitas S.J., Brion G.M., Hornung R.W., Rice C.H., Tollerud D. Increased Suicide Risk among Workers Following Toxic Metal Exposure at the Paducah Gaseous Diffusion Plant from 1952 to 2003: a Cohort Study. Int. J. Occup. Environ. Med. 2011;2;4:199–214. URL: https://stacks.cdc.gov/view/cdc/193290 (Date of Access 15.12.2025).
  49. Flanders W.D. Approximate Variance Formulas for Standardized Rate Ratios. J. Chronic Dis. 1984;37;6:449–453. Doi: 10.1016/0021-9681(84)90028-6.
  50. Смертность от внешних причин в России с середины XX века / Под ред. А.Г.Вишневского. М.: Высшая школа экономики, 2017.  448 с. [Smertnost’ ot Vneshnikh Prichin v Rossii s Serediny XX Veka = Mortality from External Causes in Russia Since the Mid-20th Century. Ed. A.G.Vishnevskiy. Moscow, Vysshaya Shkola Ekonomiki Publ., 2017. 448 (In Russ.)]. Doi: 10.17323/978-5-7598-1397-2.
  51. Котеров А.Н. От очень малых до очень больших доз радиации: новые данные по установлению диапазонов и их экспериментально-эпидемиологические обоснования // Медицинская радиология и радиационная безопасность. 2013. Т.58. №2. С. 5–21. [Koterov A.N. From Very Small to Very Large Doses of Radiation: New Data on Establishing Ranges and their Experimental and Epidemiological Justifications. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2013;58;2:5–21 (In Russ.)].
  52. Amano M.A., French B., Sakata R., Dekker M., Brenner A.V. Lifetime Risk of Suicide among Survivors of the Atomic Bombings of Japan. Epidemiol. Psychiatr. Sci. 2021;30:e43. 9 p. Doi: 10.1017/S204579602100024x.
  53. Moher D., Liberati A., Tetzlaff J., Altman D.G., PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA Statement. PLoS Med. 2009;6;7:e1000097. 6 p. Doi: 10.1371/Journal.Pmed.1000097; URL: https://legacyfileshare.elsevier.com/promis_misc/PRISMA-2009-Checklist1.pdf.
  54. Rem. Unit of Measurement. Encyclopaedia Britannica. URL: https://www.britannica.com/science/rem-unit-of-measurement (Date of Access 17.12.2025).
  55. Wilkinson G.S., Trieff N, Graham R, Priore RL. Study of Mortality among Female Nuclear Weapons Workers. Final Report. Grant Numbers: 1R01 OHO3274, R01/CCR214546, R01/CCR61 2934-01. 2000.  447 p. URL: http://www.pantex.com/RRoom/rrdocs/safetyhealth/wilkinsonfinalreport.pdf.
  56. Кокунин В.А. Статистическая обработка данных при малом числе опытов // Украинский биохимический журнал. 1975. Т.47. №6. С. 776–790. [Kokunin V.A. Statistical Processing of Data with a Small Number of Experiments. Ukrainskiy Biokhimicheskiy Zhurnal = Ukrainian Biochemical Journal. 1975;47;6:776–790 (In Russ.)].
  57. Gul M., Kotak Y., Muneer T., Ivanova S. Enhancement of Albedo for Solar Energy Gain with Particular Emphasis on Overcast Skies. Energies. 2018;11:2881. 17 p. URL: http://dx.doi.org/10.3390/en11112881.
  58. Wisenburn B., Mahoney K. A Meta-Analysis of Word-Finding Treatments for Aphasia. Aphasiology. 2009;23;11:1338–1352. Doi: 10.1080/02687030902732745.
  59. Montes A., Sanmarco J., Novo M., Cea B., Arce R. Estimating the Psychological Harm Consequence of Bullying Victimization: a Meta-Analytic Review for Forensic Evaluation. Int. J. Environ. Res. Public Health. 2022;19;13852. 9 p. Doi: 10.3390/Ijerph192113852.
  60. Park R.M., Bailer A.J., Stayner L.T., Halperin W., Gilbert S.J. An Alternate Characterization of Hazard in Occupational Epidemiology: Years of Life Lost per Years Worked. Am. J. Ind. Med. 2002;42;1:1–10. Doi: 10.1002/Ajim.10082.
  61. Waldron H.A. Did the Mad Hatter have Mercury Poisoning? Br. Med. J. (Clin. Res. Ed.). 1983;287;6409:1961. Doi: 10.1136/Bmj.287.6409.1961.
  62. Омельяновский В.В., Авксентьева М.В., Сура М.В., Хачатрян Г.Р., Федяева В.К. Методические рекомендации по проведению мета-анализа.  М.: Центр экспертизы и контроля качества медицинской помощи Минздрава России, 2017.  28 с. [Omel’yanovskiy V.V., Avksent’yeva M.V., Sura M.V., Khachatryan G.R., Fedyayeva V.K. Metodicheskiye Rekomendatsii po Provedeniyu Meta-Analiza = Methodological Recommendations for Conducting Meta-Analysis. Moscow, Tsentr Ekspertizy i Kontrolya Kachestva Meditsinskoy Pomoshchi Minzdrava Rossii Publ., 2017. 28 p. (In Russ.)].
  63. Boice J.D., Jr. Lauriston S. Taylor Lecture: Radiation Epidemiology — the Golden Age and Future Challenges. Health Phys. 2011;100;1:59–76. Doi: 10.1097/Hp.0b013e3181f9797d.
  64. Kudo S., Ishida J., Yoshimoto K., Mizuno S., Ohshima S., Furuta H., Kasagi F. Direct Adjustment for Confounding by Smoking Reduces Radiation-Related Cancer Risk Estimates of Mortality among Male Nuclear Workers in Japan, 1999–2010. J. Radiol. Prot. 2018;38;1:357–371. Doi: 10.1088/1361-6498/Aaa65c.
  65. Douglas A.J., Omar R.Z., Smith P.G. Cancer Mortality and Morbidity among Workers at the Sellafield Plant of British Nuclear Fuels. Br. J. Cancer. 1994;70;6:1232–1243. Doi: 10.1038/Bjc.1994.479.
  66. Smith S.J., Steinberg K.K., Thacker S.B. Methods for Pooled Analyses of Epidemiologic Studies. Epidemiology. 1994;5;3:381–383. Doi: 10.1097/00001648-199405000-00024.
  67. Szpiro A., Hazlehurst M., Karr C., Kaufman J., LeWinn K., Loftus C., et al. Meta-Analysis vs Pooling: Tradeoffs in Precision, Confounder Control, Mixtures, and Nonlinear Dose-Response. Abstracts of the 2019 Annual Conference of the International Society for Environmental Epidemiology. Utrecht, the Netherlands, August 25–28 2019. Environmental Epidemiology 2019;3;1:389. Doi : 10.1097/01.Ee9.0000610336.09715.B9

 

 

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Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.01.2026. Accepted for publication: 25.02.2026.