Medical Radiology and Radiation Safety. 2026. Vol. 71. № 5

DOI:10.33266/1024-6177-2026-71-5-146-149

S.N. Prokhorov¹, N.V. Kochergina^{1, 2}, A.D. Ryzhkov^{1, 2},  A.S. Krylov¹, A.B. Bludov¹, E.A. Nickolaeva¹, S.M. Kaspshik¹

RELATIONSHIP BETWEEN ANAMNESIS DATA AND RADIOGRAPHIC MANIFESTATIONS IN RELATION TO TRAUMATIC AND STRESS BONE FRACTURES IN CANCER PATIENTS

¹ N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

² Russian Medical Academy of Continuous Professional Education, Moscow, Russia

Contact person: Sergei Nickolaevich Prokhorov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

ABSTRACT

Purpose: To evaluate the relationship between anamnestic data collected from patients regarding past injuries and changes in bone scan supplemented by SPECT/CT.

Material and methods: The study included 256 cancer patients examined for metastatic disease. All patients underwent bone scintigraphy, supplemented by SPECT/CT of the area with abnormal tracer distribution.

Results: 24 (9,4%) patients out of 256 (100%) mentioned their injuries during the survey, of which 8 (3,1%) patients had corresponding changes in the obtained images in the form of increased accumulation and/or radiographic signs of fractures. In 65 (25,4%) patients out of 256 (100%), signs of focal increase in the accumulation of osteotropic radiopharmaceutical and radiographic signs of fractures in various bones were detected.

Conclusion: The obtained results demonstrate significant discrepancies between the information patients provide about their injuries and the results of bone scans, supplemented by SPECT/CT. This fact is important in the differential diagnosis of metastatic bone lesions.

Keywords: SPECT/CT, CT, bone scan, oncology, bone fractures, injuries, anamnesis data

For citation: Prokhorov SN, Kochergina NV, Ryzhkov AD, Krylov AS, Bludov AB, Nickolaeva EA, Kaspshik SM. Relationship Between Anamnesis Data and Radiographic Manifestations in Relation to Traumatic and Stress Bone Fractures in Cancer Patients. Medical Radiology and Radiation Safety. 2026;71(5):146–149. DOI:10.33266/1024-6177-2026-71-5-146-149

References

1. Sarafrazi N., Wambogo E.A., Shepherd J.A. Osteoporosis or Low Bone Mass in Older Adults: United States, 2017-2018. NCHS Data Brief. 2021 Mar;405:1-8. 

2. Bouxsein M.L., Eastell R., Lui L.Y., Wu L.A., de Papp A.E., Grauer A., Marin F., Cauley J.A., Bauer D.C., Black D.M. FNIH Bone Quality Project. Change in Bone Density and Reduction in Fracture Risk: a Meta-Regression of Published Trials. J Bone Miner Res. 2019 Apr;34;4:632-642. 

3. Kazem N.A., Esmail A.A., Elgazzar A.H. Multifocal Post-Traumatic Scintigraphic Changes Mimicking Bone Metastases in a Battered Adult. Gulf J Oncolog. 2009 Jan; 5:54-5. 

4. Kim M.J., Rinsky L.A., MacKenzie J.D. Scapular Stress Fracture Initially Masquerading as Tumor or Infection. Radiol Case Rep. 2015 Nov 6;6;4:510. 

5. Solá M., Pérez R., Cuadras P., Díaz R., Holgado S., Puyalto P., Iborra M., Fraile M. Value of Bone SPECT-CT to Predict Chronic Pain Relief after Percutaneous Vertebroplasty in Vertebral Fractures. Spine J. 2011 Dec;11;12:1102-7. 

6. Kita N., Tomita N., Takaoka T., Matsuura A., Okazaki D., Niwa M., Torii A., Takano S., Mekata Y., Niimi A., Hiwatashi A. Symptomatic Radiation-Induced Rib Fractures after Stereotactic Body Radiotherapy for Early-Stage Non-Small Cell Lung Cancer. Clin Transl Radiat Oncol. 2023 Sep 25;43:100683. 

7. Bentsen K.K., Brink C., Nielsen T.B., Lynggaard R.B., Vinholt P.J., Schytte T., Hansen O., Jeppesen S.S. Cumulative Rib Fracture Risk after Stereotactic Body Radiotherapy in Patients with Localized Non-Small Cell Lung Cancer. Radiother Oncol. 2024 Nov;200:110481. 

8. Johnston C.B., Dagar M. Osteoporosis in Older Adults. Med Clin North Am. 2020 Sep;104;5:873-884. 

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Conflict of interest. The authors declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.04.2026. Accepted for publication: 25.05.2026.