Medical Radiology and Radiation Safety. 2016. Vol. 61, No. 5. P. 54-58


A.D. Ryzhkov1, S.V. Shiryaev1, G.N. Machak2, N.V. Kochergina1, Ya.A. Shchipakhina1, A.S. Krylov1, A.S. Nered1

SPECT/CT in Treatment Monitoring of Bone Metastases of Osteosarcoma with Ultrasound Thermal Ablation Method

1. N.N. Blokhin Russian Cancer Research Center, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. N.N. Priorov Central Research Institute of Traumatology and Orthopaedics, Moscow, Russia


Purpose: To demonstrate the diagnostic capabilities to control effects of HIFU treatment in patient with osteosarcoma bone metastases by SPECT-CT method.

Material and methods: SPECT/CT treatment monitoring of the patient with bone metastases of osteosarcoma after ultrasound ablation.

Results: Metastases were detected in the SPECT/CT-pictures. The dynamic observation during the treatment was carried. The effect of the treatment caused by thermoablative manifests in the early stages (observed after 1 month). The effect of the treatment is the lack of accumulation-seeking radiopharmaceutical labeled with 99mTc in the treatment area.

Conclusion: SPECT/CT study is a demonstrative method for early determination of pathological metabolism degree at bone metastases of osteosarcoma after HIFU. SPECT/CT is an effective method of treatment monitoring of bone metastases with use of HIFU therapies.

Key words: SPECT/CT, HIFU, osteosarcoma bone metastases


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For citation: Ryzhkov AD, Shiryaev SV, Machak GN, Kochergina NV, Shchipakhina YaA, Krylov AS, Nered AS. SPECT/CT in Treatment Monitoring of Bone Metastases of Osteosarcoma with Ultrasound Thermal Ablation Method Medical Radiology and Radiation Safety. 2016;61(5):54-8. Russian.

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