JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2026. Vol. 71. № 2
DOI:10.33266/1024-6177-2026-71-2-122-128
A.A. Sazhina, A.N. Bashkov, Yu.D. Udalov, E.I. Matkevich, S.V. Lischuk
Reccurent Papillary Necrosis of the Right Kidney in the Setting of Drud-Induced Nephritis:
a Case Report on Radiologic Diagnosis
A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: A.A. Sazhina, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To present a histologically verified clinical case of renal papillary necrosis that developed as a complication of drug-induced nephritis and was accompanied by secondary obstructive suppurative destructive pyelonephritis, with an emphasis on the diagnostic capabilities of radiological imaging.
Material and methods: А clinical case of a female patient with acute suppurative destructive pyelonephritis complicated by papillary necrosis, who was hospitalized in our clinic in January–February 2018.
Results: This case highlights the diagnostic value of CT in detecting papillary necrosis and determining the extent of renal involvement, which is crucial for treatment planning. Notably, papillary necrosis developed in the absence of classical risk factors such as diabetes mellitus or long-term analgesic abuse, underlining the significance of infectious-obstructive mechanisms.
Conclusion: This case illustrates a rare and complex course of drug-induced nephritis complicated by the development of renal papillary necrosis and secondary obstructive suppurative destructive pyelonephritis. Contrast-enhanced multislice computed tomography proved to be the most informative imaging modality, revealing calicopyeloectasia, filling defects, and characteristic signs of papillary necrosis, whereas MRI was less informative due to the absence of collecting system dilatation. Renal papillary necrosis should be considered as a potential cause of gross hematuria, particularly in patients with a history of prolonged analgesic use, as early recognition of this condition may prevent severe infectious and destructive complications. This case emphasizes the importance of an integrated diagnostic approach combining clinical, laboratory, radiological, and histopathological findings to ensure accurate diagnosis and optimal management strategy.
Keywords: renal papillary necrosis, acute suppurative destructive pyelonephritis, computed tomography (CT), multislice CT (MSCT), case report, nephrectomy, clinical case
For citation: Sazhina AA, Bashkov AN, Udalov YuD, Matkevich EI, Lischuk SV. Reccurent Papillary Necrosis of the Right Kidney in the Setting of Drud-Induced Nephritis: a Case Report on Radiologic Diagnosis. Medical Radiology and Radiation Safety. 2026;71(2):122–128. DOI:10.33266/1024-6177-2026-71-2-122-128
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.02.2026. Accepted for publication: 25.03.2026.