SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

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The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

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The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 87–96

T.V. Azizova, M.V. Bannikova, E.S. Grigoryeva, G.V. Zhuntova, M.B. Moseeva, E.V. Bragin

Registry for Chronic Radiation Sickness in a Cohort of Mayak PA Workers Exposed to Ionizing Radiation

Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To present descriptive characteristics, and structure of the chronic radiation sickness (CRS) registry prospects of its use.

Material and methods: A registry for CRS diagnosed in workers of the nuclear production facility Mayak Production Association (PA) throughout the follow-up period of 1948–2018 was established within a medical and dosimetry database ‘Clinic’ of the Southern Urals Biophysics Institute.

Results: The CRS registry includes 2068 cases: 1517 (73.4 %) in males and 551 (26.6 %) in females. Almost all workers (97.9 %) with CRS were hired at the Mayak PA in 1948–1954 and chronically externally and/or internally exposed to ionizing radiation. At a date of CRS diagnosis the mean cumulative red bone marrow absorbed dose of external exposure to gamma rays was 1.1 ± 0.7 Gy in males and 1.0 ± 0.6 Gy in females; the mean annual dose was 0.46 ± 0.33 Gy and 0.38 ± 0.22 Gy in males and females, respectively; maximum annual dose was 0.67 ± 0.46 Gy and 0.55 ± 0.34 Gy in males and females, respectively. The CRS frequency in the Mayak PA worker cohort significantly increased with the cumulative and mean annual RBM absorbed dose of external exposure to gamma rays. In the meantime, the CRS frequency was not associated either with a dose of external neutron exposure or with a dose of internal exposure to alpha particles from incorporated plutonium.

Conclusion: The established CRS registry providing complete high quality demographical, medical and dosimetry information, together with available biological specimens, in future will allow: the updating of dose–response and dose–time–response relationships; the estimation of latent periods, risks and dose thresholds and associated uncertainties for CRS development; certain tissue reactions in lymphoid and haematopoietic tissues; and a better understanding of their development patterns and mechanisms, taking into account non-radiation factors.

Key words: chronic gamma-ray exposure, chronic radiation sickness, red bone marrow, occupational radiation exposure, Mayak PA

For citation: Azizova TV, Bannikova MV, Grigoryeva ES, Zhuntova GV, Mosseva MB, Bragin EV. Registry for Chronic Radiation Sickness in a Cohort of Mayak PA Workers Exposed to Ionizing Radiation. Medical Radiology and Radiation Safety. 2020;65(4):87-96 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-87-96

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Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 29.07.2020. Принята к публикации: 12.08.2020.
Article received: 29.07.2020. Accepted for publication: 12.08.2020.

Information about the autors:

Azizova T.V. http://orcid.org/0000-0001-6954-2674
Bannikova M.V. http://orcid.org/0000-0002-2755-6282
Grigoryeva E.S. http://orcid.org/0000-0003-1806-9922
Zhuntova G.V. http://orcid.org/0000-0003-4407-3749
Moseeva M.B. http://orcid.org/0000-0003-3741-6600
Bragin E.V. http://orcid.org/0000-0003-0410-5048


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