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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

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Medical Radiology and Radiation Safety. 2021. Vol. 66. № 5. P. 66–77

Topical Issues of Radiopharmaceuticals Appliance in PET Studies

A.V. Khmelev1,2 

1Research Institute – Federal research Center for Project Evaluation and Consulting Services, Moscow, Russia

2Russian Medical Academy of Continuous Professional Education, Moscow, Russiaa

Contact person: Aleksandr Vasilyevich Khmelev: This email address is being protected from spambots. You need JavaScript enabled to view it.

CONTENT

Introduction 

1. Requirements to radiopharmaceuticals

2. Factors affecting the biodistribution in organism

3. Uptake and localization mechanisms

4. Appliance in PET studies of biological processes and diagnostics

5. Aspects of regulation of radiopharmaceuticals circulation

Conclusion 

Key words: radiopharmaceuticals, radionuclide, localization mechanism, PET 

For citation: Khmelev AV. Topical Issues of Radiopharmaceuticals Appliance in PET StudiesSupport of Occupational Radiation Protection during. Medical Radiology and Radiation Safety. 2021;66(5):66-77.

DOI: 10.12737/1024-6177-2021-66-5-66-77

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 PDF (RUS) Full-text article (in Russian)

 

Conflict of interest. The author declare no conflict of interest.

Financing. The study had no sponsorship.

Contribution. Article was prepared with equal participation of the authors

Article received: 23.12.2020. 

Accepted for publication: 20.01.2021. 

 

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