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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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Medical Radiology and Radiation Safety. 2021. Vol. 66. № 6. P. 63–70
Current Trends in Targeted Radionuclide Therapy Development
M.S. Vorontsova, T.A. Karmakova, A.A. Pankratov, A.D. Kaprin
P.A. Hertsen Moscow Oncology Research Institute. Moscow, Russia
Contact person: Tatyana Anatolyevna Karmakova, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
CONTENT
Introduction
1. Features of Targeted Delivery of Therapeutic Radionuclides
2. Design of Pharmaceuticals for Targeted Radionuclide Therapy (TRT)
2.1. Radionuclides
2.2. Synthesis of Radioconjugates
2.3. Targeting Carriers
4. Subcellular Targeting of Radionuclides
5. TRT Dosimetry
Conclusion
Key words: cancer, solid tumors, targeted radionuclide therapy
For citation: Vorontsova MS, Karmakova TA, Pankratov AA, Kaprin AD. Current Trends in Targeted Radionuclide Therapy Development. Medical Radiology and Radiation Safety. 2021;66(6):63–70.
DOI: 10.12737/1024-6177-2021-66-6-63-70
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 23.12.2020.
Accepted for publication: 20.01.2021.