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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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Medical Radiology and Radiation Safety. 2022. Vol. 67. № 1
Analysis of the Risk of Death from cerebrovascular Disease of
Liquidators of the Consequences of the Accident at the Chernobyl NPP, Employees of the Atomic Industry
I.L. Shafransky, A.R. Tukov, O.N. Prohorova, M.V. Kalinina
A.I. Burnasyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: Tukov Alexander Romanovich, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Assessment of the risk of death of the liquidators of the Chernobyl accident from cerebrovascular diseases.
Material and methods: The risk of death of liquidators of the Chernobyl accident from cerebrovascular diseases (ICD 10: I60-I69.9) was estimated using the Industry Register of persons exposed to radiation as a result of the Chernobyl accident over a thirty-year period, with a verified dose of external exposure obtained by operating in the 30 km zone of the Chernobyl NPP. The study included men - 12,663 people, 1327 of them have a dose of occupational exposure. Rough relative risks of mortality from cerebrovascular diseases were evaluated for five dose groups based on internal control. At the second stage of the study, all data were stratified by age, dose load and Follow up period. Based on the obtained stratified data file, the Poisson regression procedure was carried out, for which the Epicure AMFIT module was used and the magnitude of the excess relative risk (ERR) of death from cerebrovascular diseases was calculated and the nature of the dose dependence of EI was investigated. A cohort epidemiological study of a group of liquidators of 1986-1990 was conducted over a thirty-year period, depending on the dose, both obtained during the liquidation of the consequences of the Chernobyl accident and during work with radioactive substances (RS) in the profession.
Results: For the first time, direct estimates of the radiogenic risk of death from cerebrovascular diseases have been obtained. A risk decrease in this type of death per unit dose was shown for dose loads implemented during the liquidation of the consequences of the Chernobyl accident and professional doses too.
Conclusion: Liquidators in the long-term after the work on eliminating the consequences of the accident need generally accepted medical care approaches aimed at preventing and treating such common diseases as cardiovascular diseases. The results can be used in the development of radiation safety regulation.
Keywords: radiation, risk of death, relative risk, cerebrovascular disease, the Chernobyl accident, EPICURE, AMFIT, ROSATOM, radiation safety
For citation: Shafransky IL, Tukov AR, Prohorova ON, Kalinina MV. Analysis of the Risk of Death from cerebrovascular Disease of Liquidators of the Consequences of the Accident at the Chernobyl NPP, Employees of the Atomic Industry. Medical Radiology and Radiation Safety. 2022;67(1):60-64.
DOI: 10.12737/1024-6177-2022-67-1-60-64
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PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 05.06.2021.
Accepted for publication: 15.12.2021