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The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
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Medical Radiology and Radiation Safety. 2023. Vol. 68. № 1
DOI: 10.33266/1024-6177-2023-68-1-58-71
O.K. Kurpeshev
Threshold Thermal Dose of Local Hyperthermia in Thermoradiation Therapy of Tumors
Siberian Scientific Research Institute of Hyperthermia, Novosibirsk
Contact person: Orazakhmet Kurpeshev, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Contents
The review analyzes the damaging, radio- and chemosensitizing effects of various temperature regimes of hyperthermia on normal and tumor cells in the experiment and on the results of thermoradiation therapy for cancer patients. According to the criteria of minimum, average and maximum temperatures, as well as the cumulative equivalent time for heating 90 % of the tumor volume at 43 °C (CEM43T90), lower threshold thermal doses have been determined that significantly affect the immediate results of thermoradiation therapy. The maximum allowable temperatures for normal skin and with postoperative scars or radiation fibrosis have been established.
Keywords: hyperthermia, thermal dose, chemotherapy, thermoradiotherapy, thermochemotherapy. thermochemoradiotherapy
For citation: Kurpeshev OK. Threshold Thermal Dose of Local Hyperthermia in Thermoradiation Therapy of Tumors. Medical Radiology and Radiation Safety. 2023;68(1):58–71. (In Russian). DOI: 10.33266/1024-6177-2023-68-1-58-71
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Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.09.2022. Accepted for publication: 25.11.2022.