JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2023. Vol. 68. № 6
DOI:10.33266/1024-6177-2023-68-6-60-66
A.R. Tukov, I.L. Shafransky, O.N. Prokhorova, A.M. Mikhailenko, M.N. Ziyatdinov
Diabetes Mellitus Incidence and the Risk of its Occurrence in Liquidators of the Chnpp Accident Consequences including Nuclear Industry Workers
A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: A.R. Tukov, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Summary: Investigation purposes Diabetes mellitus (DM) occupies the largest share in the structure of endocrine system diseases, nutritional disorders and metabolic disorders, which is currently one of the important priorities of national health systems. Research on certain groups of the population with their own harmful occupational risk factors is relevant. Analysis of the incidence of diabetes mellitus of the second type - T2DM (ICD 10: E11-E11.9) of liquidators of the consequences of the Chernobyl accident ‒ workers of nuclear industry enterprises for 30 years of observation and assessment of the radiation risk of its occurrence.
Material and methods: The study includes data from the Industry register of persons exposed to radiation as a result of the Chernobyl accident over a thirty-year period, having a verified dose of external radiation received during work in the 30 km zone of the Chernobyl nuclear power plant, men – 12663 people, 1327, of whom have data on the dose of occupational irradiation. The Poisson process with an intensity parameter was chosen as a statistical model of morbidity.
Results: The incidence of T2DM in liquidators of the consequences of the Chernobyl accident was estimated by age and sex groups. On the basis of the obtained file of individual unstratified data, an analytical likelihood function for the Poisson process was constructed and the value of the excess relative risk (ERR) of T2DM incidence was calculated and the nature of the dose dependence of RR was investigated.
A cohort epidemiological study of a group of liquidators in 1986–1990 was carried out. over a thirty-year period, depending on the dose, both received during the liquidation of the consequences of the Chernobyl accident, and during professional work with radioactive substances (RS) and sources of ionizing radiation (IRS). Direct estimates of the radiogenic risk of diabetes mellitus are given. Different values of risk were noted when using doses from different types of radiation. There was no significant increase in the risk of disease per dose unit (ERR / Sv).
Conclusion: With the aging of the cohort of liquidators, an increase in the incidence of T2DM was noted in both men and women. The results obtained on the assessment of the radiation risk of T2DM at this stage are taken as preliminary, since the use of radiation risk in the development of radiation safety regulations requires a total dose from all types of exposure (professional, emergency, medical, natural).
Keywords: diabetes, incidence, radiation, relative risk, overweight, Chernobyl accident, employees of the nuclear industry, sectoral register
For citation: Tukov AR, Shafransky IL, Prokhorova ON, Mikhailenko AM, Ziyatdinov MN. Diabetes Mellitus Incidence and the Risk of its Occurrence in Liquidators of the Chnpp Accident Consequences including Nuclear Industry Workers. Medical Radiology and Radiation Safety. 2023;68(6):60–66. (In Russian). DOI:10.33266/1024-6177-2023-68-6-60-66
References
1. Dedov I.I. Diabetes Mellitus – the Most Dangerous Challenge to the World Community. Vestnik Rossiiskoy Akademii Meditsinskikh Nauk = Annals of the Russian Academy of Medical Sciences. 2012;1:7-13 (In Russ.).
2. Dedov I.I., Shestakova M.V., Suntsov Yu.I., et al. Federal Targeted Programme ‘Prevention and Management of Socially Significant Diseases (2007-2012)’: Results of the ‘Diabetes Mellitus’ Sub-Programme. Sakharnyy Diabet = Diabetes Mellitus. 2013;16;2S:2-48 (In Russ.).
3. IDF Diabetes Atlas. Brussels, Belgium, International Diabetes Federation, 2015. URL: http://www.diabetesatlas.org/.
4. Maslova OV., Suntsov Yu.I. Epidemiology of Diabetes Mellitus and Microvascular Complications. Sakharnyy Diabet = Diabetes Mellitus. 2011;3:6-12 (In Russ.).
5. American Diabetes Association. Economic Costs of Diabetes in the U.S. in 2012. Diabetes Care. 2013;36;4:1033–1046.
6. Dedov I.I. Algorithms of Specialized Medical Care Patients with Diabetes. Ed. Dedov I.I., Shestakova M.V. Moscow Publ., 2015. P. 7-112 (In Russ.).
7. Vologodskaya I.A., Fomin E.A., Kovin A.I. Improving the Medical Monitoring System for Employees of the Nuclear Industry Enterprises. Meditsina: Tselevyye Proyekty. 2014;19:35-37 (In Russ.).
8. Vologodskaya I.A., Kurbatov A.V., Grigor’eva E.S. Predisposition to Multifactorial Pathology in Residents of the City in the Zone Around the “Maiak” Atomic Industry Enterprise. Radiats. Biol. Radioecol. 2002;42;6:690-692.
9. Pishhugina A.V., Ivanov A.G., Belyakova N.A. Features of the Incidence of Nuclear Energy Operating at the Enterprise. Problemy Sotsialnoy Gigiyeny, Zdravookhraneniya i Istorii Meditsiny = Problems of Social Hygiene, Public Health and History of Medicine. 2013;1:18-21 (In Russ.).
10. Florent de Vathaire, Chiraz El-Fayech, Faten Fedhila Ben Ayed, et. al. Radiation Dose to the Pancreas and Risk of Diabetes Mellitus in Childhood Cancer Survivors: a Retrospective Cohort Study. Lancet Oncol. 2012;13;10:1002-1010. doi: 10.1016/S1470-2045(12)70323-6.
11. A van Nimwegen F., Schaapveld M., Janus C.P.M., et. al. Risk of Diabetes Mellitus in Long-Term Survivors of Hodgkin Lymphoma. J. Clin. Oncol. 2014;32;29б:3257-3263. doi: 10.1200/JCO.2013.54.4379.
12. Meacham L.R., Sklar C.A., Li S., et. al. Diabetes Mellitus in long-term Survivors of Childhood Cancer. Increased Risk Associated with Radiation Therapy: a Report for the Childhood Cancer Survivor Study. Arch. Intern. Med. 2009;169;15:1381-1388. doi: 10.1001/archinternmed. 2009. 209.
13. Breslow N.E., Day N.E. Statistical Methods in Cancer Research. V. I. The Analysis of Case-Control Studies. IARC Scientific Publication No. 32. Lyon, IARC, 1980.
14. Preston D.L., Lubin D.B., Pierce D.A., McConney M.E. Epicure Users Guide. Seattle, WA, Hirosoft Inter-National Corporation, 1993. 330 p.
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The work was carried out as part of the implementation of the State Order.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.07.2023. Accepted for publication: 27.08.2023.