JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2024. Vol. 69. № 4
DOI:10.33266/1024-6177-2024-69-4-48-54
F.S. Torubarov, M.V. Kuleshova, N.A. Metlyaeva, S.N. Lukyanova
Studying the State of the Autonomic Nervous System and Hemodynamics in the Liquidators of the Accident
at the Chernobyl NPP
A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia
Contact person: N.A. Metlyaeva, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: Comparative analysis of changes in the state of the autonomic nervous system and hemodynamics in liquidators of the consequences of the Chernobyl accident and individuals in the comparison group exposed to low doses of ionizing radiation.
Material and methods: The study was carried out for 141 liquidators of the consequences of the Chernobyl accident and 84 male comparison group people aged from 30 to 50 years (41.24 ± 0.41) and (40.95 ± 0.54), respectively. Only liquidators could be exposed to ionizing effects. All of them, the dose of ionizing radiation did not exceed 0.5 Gy. All individuals underwent a clinical, neurological and electrophysiological examination in A.I. Burnazyan Federal Medical Biophysical Center. The main attention was paid to studying the state of the autonomic nervous system and hemodynamics in participants in the liquidation of the consequences of the Chernobyl accident.
Results: Clinical examination made it possible to diagnose neurological disorders in both groups in the form of: vegetative-vascular dystonia, neurocirculatory dystonia, dyscirculatory encephalopathy of various etiologies ‒ with a statistically significant predominance of their quantity and quality among liquidators. The changes observed in liquidators are functional and nonspecific.
Conclusions: In the group of liquidators, a significant increase in the number and severity of the considered neurological disorders was revealed. Comparison of the examined groups according to the state of central hemodynamics showed the absence of a statistically significant connection between the state of cerebral blood flow and low-dose irradiation. At the same time, a connection was established between the state of cerebral hemodynamics and systemic autonomic tone and the age of the examined individuals. The combination of permanent and paroxysmal autonomic disorders, psychosomatic disorders can be considered as a manifestation of hypothalamic dysfunction that has developed against the background of vascular disorders in the brain that have arisen with age.
Keywords: accident at Chernobyl NPP, liquidators, autonomic nervous sistem, hemodynamics, functional diagnostics
For citation: Torubarov FS, Kuleshova MV, Metlyaeva NA, Lukyanova SN. Studying the State of the Autonomic Nervous System and Hemodynamics in the Liquidators of the Accident at the Chernobyl NPP. Medical Radiology and Radiation Safety. 2024;69(4):48–54.
(In Russian). DOI:10.33266/1024-6177-2024-69-4-48-54
References
1. Guskova AK, Soldatova VA, Denisova EA, et al. Long-term Consequences of Occupational Radiation Exposure. Meditsinskaya Radiologiya = Medical Radiology. 1976(4):34-40 (In Russ.).
2. Grigoriev Yu.G. Effects of Long-term Chronic Gamma Irradiation. Biologicheskiye Effekty Malykh Doz Radiatsii. Sbornik Nauchnykh Trudov = Biological Effects of Low Doses of Radiation: Collection of Scientific Papers. Moscow Publ., 1983. P. 11-20 (In Russ.).
3. Torubarov F.S. Kliniko-Fiziologicheskaya Kharakteristika Tserebral’noy Gemodinamiki pri OLB Cheloveka i yeye Posledstviyakh = Clinical and Physiological Characteristics of Cerebral Hemodynamics in Human Ars and its Consequences. Doctor’s thesis (Med.). Moscow Publ., 1983 (In Russ.).
4. Guskova A.K. Radiation: Imaginary and Real Dangers (Regulatory and Methodological Materials on Radiation Medicine of the USSR Ministry of Health). Moscow Publ., 1990. P. 5-11 (In Russ.).
5. Dakhno D.V. Izucheniye Sostoyaniya Vegetativnoy Nervnoy Sistemy u Lits, Prinimavshikh Uchastiye v Likvidatsii Posledstviy Avarii na CHAES = Study of the State of the Autonomic Nervous system in Persons Who Took Part in the Liquidation of the Consequences of the Chernobyl Accident. Doctor’s thesis (Med.). Moscow Publ., 1990. P. 145-154 (In Russ.).
6. Voloshin PV, Kryzhenko TV, Zdesenko IV. Clinical and Clinical-Physiological Features of Cerebrovascular Disorders in Persons Exposed to Radiation. Izmeneniye Nervnoy Sistemy Cheloveka pri Deystvii Ioniziruyushchey Radiatsii = Changes in the Human Nervous System under the Influence of Initiating radiation. Materials of the All-union Conference. Ed. F.S.Torubarov. Moscow Publ., 1990. P. 91-95 (In Russ.).
7. Gordon I.B, Gordon A.I. Tserebral’nyye i Perifericheskiye Vegetativnyye Rasstroystva v Klinicheskoy Kardiologii = Cerebral and Peripheral Autonomic Disorders in Clinical Cardiology. Moscow, Medicine Publ., 1994. P. 6-8 (In Russ.).
8. Ananyeva V.M. Psychovegetative Disorders in Persons Exposed to Relatively Low Doses of Radiation. Vserossiyskiy S”Yezd Nevrologov = All-Russian Congress of Neurologists: Abstracts of Reports. Nizhny Novgorod Publ., 1995. P. 520-521 (In Russ.).
9. Torubarov FS, Kuleshova MV, Lukyanova SN, Zvereva ZV, Samoilov AS. Spectral-Correlation Analysis of EEG in Liquidators of the Chernobyl Accident with Neurological Disorders. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 2019;64(3):40-45 (In Russ.).
10. Baranov AE, Guskova AK, Protasova TG. Experience in Treating Victims of the Accident at the Chernobyl Nuclear Power Plant and Immediate Outcomes of the Disease. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 1991;36(3):29-32 (In Russ.)
11. Bushmanov A.Yu. Kliniko-Epidemiologicheskoye Issledovaniye Razvitiya Mozgovykh Insul’tov u Zhiteley Zakrytogo Administrativno-Territorial’nogo Obrazovaniya Zapadnoy Sibiri (g. Seversk) = Clinical and Epidemiological Study of the Development of Cerebral Strokes in Residents of a Closed Administrative-Territorial Entity of Western Siberia (Seversk). Doctor’s thesis (Med.). Moscow Publ., 1997. P. 34-38 (In Russ.).
12. Guskova AK. Ten Years After the Chernobyl Accident (Retrospective of Clinical Events and Measures to Overcome the Consequences). Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 1997:42(1):5-12 (In Russ.).
13. Guskova AK, Denisova EA. Basic Physiological Indicators of the Cardiovascular System of Practically Healthy People. Fiziologiya Cheloveka = Human Physiology. 1975(2):302-309 (In Russ.).
14. Guskova A.K., Shakirova I.N. Reaction of the Nervous System to Damaging Ionizing Radiation. Review. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova = S.S. Korsakov Journal of Neurology and Psychiatry. 1989:89(2):138-142 (In Russ.).
15. Guskova AK, Yarmoninko SP. Essay on the Radiation Effects of the Atomic Bombing. Review. Meditsinskaya Radiologiya i Radiatsionnaya Bezopasnost’ = Medical Radiology and Radiation Safety. 1995:40(6):67-69 (In Russ.)
16. Denisova E.A. Sostoyaniye Serdechno-Sosudistoy Sistemy pri Khronicheskom Luchevom Vozdeystvii v Professional’nykh Usloviyakh = State of the Cardiovascular System during Chronic Radiation Exposure in Professional Conditions. Doctor’s thesis (Med.). Moscow Publ., 1970. 425 p. (In Russ.).
17. Serdechno-Sosudistaya Sistema pri Deystvii Professional’nykh Faktorov = Cardiovascular System under the Influence of Professional Factors. Ed. N.M. Konchalovskaya. Moscow Publ., 1976. 256 p. (In Russ.).
18. Ternov V.I. Gigiyenicheskaya Znachimost’ Vozdeystviya na Organizm Ioniziruyushchey Radiatsii Maloy Intensivnosti (Naturnyye i Eksperimental’no-Laboratornyye Issledovaniya) = The Hygienic Significance of the Impact on the Body of Low-intensity Ionizing Radiation (Field and Experimental Laboratory Studies). Moscow Publ., 1986. 43 p. (In Russ.).
19. Barbarenko N.I, Denisova E.A, Pavlova I.V. Functional State of the Sympathetic-Adrenal System during Occupational Exposure. Meditsinskaya Radiologiya = Medical Radiology. 1975;(9):46-52 (In Russ.).
20. Guskova A.K. Using Medical Observation Data of Workers Working with Radiation Sources to Substantiate the “Risk” of Occupational Exposure. Meditsinskaya Radiologiya = Medical Radiology. 1980(11):41-46 (In Russ.).
21. Guskova A.K, Denisova E.A, Seltser V.K., et al. Results of Clinical and Physiological Observations of Persons Exposed to Occupational Exposure. Meditsinskaya Radiologiya = Medical Radiology. 1975(9):36-46 (In Russ.).
22. Bolotnikov V.M, Mikhailov M.A, Nechaeva V.I., et al. Organization and Main Tasks of Dispensary Observation of Workers Working with Sources of Non-Ionizing Radiation. Rentgenologiya i Radiologiya = Radiology and Radiology. 1981(2):128-131 (In Russ).
23. Kiryushkin V.I, Guskova A.K, Kosenko N.M. Organization of Observation of a Limited Part of the Population in Conditions of Increased Exposure. Rukovodstvo po Organizatsii Meditsinskogo Obsluzhivaniya Lits, Podvergshikhsya Deystviyu Ioniziruyushchego Izlucheniya = Guidelines for the Organization of Medical Care for Persons Exposed to Ionizing Radiation. Moscow, Energoizdat Publ., 1981;(2):128-131 (In Russ.).
24. Zakharova A.V. On the Effect of Low Doses of Ionizing Radiation on the State of Some Hemodynamic Parameters in People Working at Accelerators. Izbrannyye Materialy Byulletenya Radiatsionnoy Meditsiny = Selected Materials Bulletin of Radiation Medicine. 1970;2:52-55 (In Russ.)
25. Vorobyov E.I, Stepanov R.P. Ioniziruyushcheye Izlucheniye i Krovenosnyye Sosudy = Ionizing Radiation and Blood Vessels. Moscow, Energoatomizdat Publ., 1985. 293 p. (In Russ.).
26. Zenkov L.R, Ronkin M.A. Funktsional’naya Diagnostika Nervnykh Bolezney = Functional Diagnosis of Nervous Diseases. Moscow, Meditsina Publ., 1982. 432 p. (In Russ.).
27. Mekhanizmy Sistemnoy Regulyatsii Mozga = Mechanisms of Systemic Regulation of the Brain. Ed. Rudakova K.V., Chirkova A.I. Gor’kiy Publ., 1978. P. 348-355 (In Russ.).
28. Sudakov K.V., Yumatov Ye.A., Ul’yaninskiy L.S. Systemic Mechanisms of Emotional Stress. 8-y Vsesoyuznyy S”Yezd Nevropatologov, Psikhiatrov i Narkologov = 8th All-Union Congress of Neuropathologists, Psychiatrists and Narcologists. Materials. 25-28 October, 1988, Moscow. Moscow, Institute of Normal Physiology named after. P.K.Anokhin Publ., 1988. V.3. Pp. 52-63 (In Russ.).
29. Pribylova N.N., Koren V.S, Sidorets V.M, Beznosov N.S, Fomin A.V., Neronov A.F. Features of Neurocirculatory Dystonia under the Influence of Ionizing Radiation. Vsesoyuznaya Nauchnaya Konferentsiya = All-Union Scientific Conference 30-31 May, 1989. Moscow Publ., 1989. P. 67-74 (In Russ.).
PDF (RUS) Full-text article (in Russian)
Conflict of interest. The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.03.2024. Accepted for publication: 25.04.2024.