JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Medical Radiology and Radiation Safety. 2017. Vol. 62. No. 5. P. 33-39

DIAGNOSTIC RADIOLOGY

DOI: 10.12737/article_59f2fc0812bc46.45377149

The Advantage of a Combined SPECT/CT in the Diagnosis of Bone Metastases

A.D. Ryzhkov, A.S. Krylov, S.V. Shiryaev, Ya.A. Shchipakhina, N.V. Kochergina

N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

A.D. Ryzhkov – Senior Researcher, Dr. Sc. Med.; A.S. Krylov – Radiologist, PhD Med., Member of the European Association of Nuclear Medicine and Molecular Imaging; S.V. Shiryaev – Head of Lab., Dr. Sc. Med., prof., President of the OSMI, member of the European Association of Nuclear Medicine and Molecular Imaging, member of the American College of Nuclear Medicine and Molecular Imaging, member of the Society of Nuclear Medicine and Molecular Imaging; Ya.A. Shchipakhina – Research worker, PhD Med.; N.V. Kochergina – Leading Researcher, Dr. Sc. Med., Prof.

Abstract

Purpose: To define the diagnostic capabilities of SPECT/CT in comparison with whole body scintigraphy (WBS) in patients with bone metastases. Material and methods: It was included 67 patients with bone metastases of breast cancer, prostate cancer and other tumors. The evaluation was included WBS and SPECT/CT.

Results: All patients were divided into 2 groups: with single and multiple metastases. SPECT/CT showed higher efficiency in detecting bone metastases than WBS. The full detection of bone metastases with WBS ranged from 31 to 56 % compared to SPECT/CT for groups respectively. In some cases (for groups respectively 4 to 9.5 % depending on the number of metastases and their localization) of WBS was not informative, recorded the absence of lesions.

Conclusion: SPECT/CT can improve the diagnosis of bone metastasis.

Key words: bone metastases, SPECT/CT, bone scan

REFERENCES

  1. Chakraborty D., Bhattacharya A., Mete U.K., Mittal B.R. Comparison of 18F fluoride PET/CT and 99mTc-MDP bone scan in the detection of skeletal metastases in urinary bladder carcinoma. Clin. Nucl. Med. 2013. Vol. 38. No. 8. P. 616–621. Doi:10.1097/RLU.0b013e31828da5cc.
  2. Qiu Z.L., Xue Y.L., Song H.J., Luo Q.Y. Comparison of the diagnostic and prognostic values of 99mTc-MDP-planar bone scintigraphy, 131I-SPECT/CT and 18F-FDG-PET/CT for the detection of bone metastases from differentiated thyroid cancer. Nucl. Med. Commun. 2012. Vol. 33. No. 12. P. 1232–1242. Doi: 10.1097/MNM.0b013e328358d9c0.
  3. Shen G., Deng H., Hu S., Jia Z. Comparison of choline-PET/CT, MRI, SPECT, and bone scintigraphy in the diagnosis of bone metastases in patients with prostate cancer: a meta-analysis. Skeletal Radiol. 2014. Vol. 43. No. 11. P. 1503–1513. Doi: 10.1007/s00256-014-1903-9.
  4. Shen C.T., Qiu Z.L., Han T.T., Luo Q.Y. Performance of 18F-fluoride PET or PET/CT for the detection of bone metastases:a meta-analysis. Clin. Nucl. Med. 2015. Vol. 40. No. 2. P. 103–110. Doi: 10.1097/RLU.0000000000000592.
  5. Buck A.K., Nekolla S., Ziegler S. et al. SPECT/CT . J. Nucl. Med. 2008. Vol. 49. No. 8. P. 1305–1319. Doi: 10.2967/jnumed.107.050195.
  6. Ryzhkov A.D., Ivanov S.M., Shiryaev S.V. et al. SPECT/CT radiation in treatment of bone metastases of osteosarcoma. Problems in oncology. 2016. Vol. 62. No. 5. P. 654–659.
  7. Haraldsen A., Bluhme H., Røhl L. et al. Single photon emission computed tomography (SPECT) and SPECT/low-dose computerized tomography did not increase sensitivity or specificity compared to planar bone scintigraphy for detection of bone metastases in advanced breast cancer. Clin. Physiol. Funct. Imaging. 2016. Vol. 36. No. 1. P. 40–46. Doi: 10.1111/cpf.12191.
  8. Palmedo H., Marx C., Ebert A. et al. Whole-body SPECT/CT for bone scintigraphy: diagnostic value and effect on patient management in oncological patients . Eur. J. Nucl. Med. Mol. Imaging. 2014. Vol. 41. No. 1. P. 59–67. Doi: 10.1007/s00259-013-2532-6.
  9. Ahmadzadehfar H., Marx C., Ebert A. et al. Diagnostic accuracy of SPECT/CT in comparison to whole body scintigraphy and SPECT in patients with suspected osseous metastases: Results of a two center study. J. Nucl. Med. 2012. Vol. 53. Suppl. 1. P. 336.
  10. Savelli G., Maffioli L., Maccauro M. et al. Bone scintigraphy and the added value of SPECT (single photon emission tomography) in detecting skeletal lesions. Q. J. Nucl. Med. 2001. Vol. 45. Np. 1. P. 27–37.
  11. Löfgren J., Mortensen J., Loft A. et al. Diagnosing bone metastases. Pilot data from a prospective study comparing [99mTc]-MDP planar bone scintigraphy, whole body SPECT/CT, [18F]-fluoride PET/CT and [18F]-fluoride PET/MRI. J. Nucl. Med. 2013. Vol. 54. No. 2. P. 92–93.
  12. Krzhivitsky P.I., Kanaev S.V., Novikov S.N. et al. SPECT-CT in the diagnosis of metastatic skeletal lesion. Problems in oncology. Vol. 60, No. 1. P. 56–63.
  13. Cuccurullo V., Cascini G.L., Tamburrini O. et al. Bone metastases radiopharmaceuticals: an overview. Curr. 2013. 6. P. 41–47.
  14. Ginde A.A., Foianini A., Renner D.M. et al. Availability and quality of computed tomography and magnetic resonance imaging equipment in U.S. emergency departments . Acad. Emerg. Med. 2008. Vol. 15. No. 8. P. 780–783. Doi: 10.1111/j.1553-2712.2008.00192.x.
  15. Górska-Chrzastek M., Kovacevicz-Kusmierek K., Chrzastek J. et al. Reliability of different radioisotopic techniques in diagnosing solitary hot spots in the spine of patients with malignant neoplasm. Pol. Arch. Med. Wewn. 2013. Vol. 123. No. 7–8. P. 386–393.
  16. Ryzhkov A.D., Shiryaev S.V., Odzharova A.A., Aplevich N.N., Krylov A.S., Goncharov M.O. 99m-Tc-labelled Phosphonate Metastases Bone Scintigraphy. Radiol. and Radiation Safety. 2007. Vol. 52, No. 4. P. 62–68.
  17. O’Sullivan G.J., Carty F.L., Cronin C.G. Imaging of bone metastasis: An update. World. J. Radiol. 2015. Vol. 28. Suppl. No. 8. P. 202–211. Doi: 10.4329/wjr.v7.i8.202.

For citation: Ryzhkov AD, Krylov AS, Shiryaev SV, Shchipakhina YaA, Kochergina NV. The Advantage of a Combined SPECT/CT in the Diagnosis of Bone Metastasesn. Medical Radiology and Radiation Safety. 2017;62(5):33-9. Russian. DOI: 10.12737/article_59f2fc0812bc46.45377149

PDF (RUS) Full-text article (in Russian)

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