JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Medical Radiology and Radiation Safety. 2018. Vol. 63. No. 4. P. 15-21
RADIATION MEDICINE
DOI: 10.12737/article_5b83b0430902e8.35861647
Risk Assessment of Senile Cataract Incidence in a Cohort of Nuclear Workers of Mayak Production Association
T.V. Azizova1, E.V. Bragin1, N. Hamada2, M.V. Bannikova1
1. Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Radiation Safety Research Center, Nuclear Technology Research Laboratory, Central Research Institute of Electric Power Industry, Tokyo, Japan
T.V. Azizova - Deputy Director, Head of Clinical Dep., PhD Med., ICRP Member, UNSCEAR Member; E.V. Bragin - Junior Researcher; N. Hamada - Researcher, PhD, ICRP Member; M.V. Bannikova - Junior Researcher
Abstract
Purpose: To estimate incidence risk for senile cataracts in a cohort of workers employed at nuclear production facility, that were occupationally exposed to radiation taking into account non-radiation risk factors.
Material and methods: Senile cataract incidence (cataracts) is studied in the cohort of Mayak PA workers first employed at one of the main facilities (reactors, radiochemical or plutonium production plants) during 1948-1982 (22,377 individuals). All members of the study cohort were occupationally exposed to gamma-rays or neutrons over a prolonged period. Absorbed doses from external and/or neutron exposure used in the study were provided by MWDS-2008. Relative risk (RR) and excess relative risk per unit dose (ERR/Gy) were estimated based on maximum likelihood using AMFIT module of EPICURE software.
Results: 4159 cataract diagnoses were verified in the study cohort of workers during 482217 person-years of follow-up. The majority of cataracts were diagnosed in cohort members included in the age group 61-70 years old in both males and females. The mean age at cataract diagnosis was 63.1 ± 0.2 years in males and 64.8 ± 0.2 years in females, respectively. RR of cataract incidence was statistically significant in all dose categories when compared to a reference category (0-0.25 Gy) and increased with increasing dose from external gamma-rays and was the highest in workers exposed to external gamma-rays at doses exceeding 2.0 Gy (1.61 95 % CI: 1,41-1,83). Significant linear association of cataracts with dose from external gamma-rays was observed with ERR/Gy = 0.28 (95 % CI: 0.20, 0.37). The risk estimate varied slightly with inclusion of additional adjustments for different non-radiation factors (smoking status and alcohol consumption, smoking index, hypertension, body mass index, severe myopia diagnosed). After adjusting for dose from neutrons ERR/Gy of external gamma-rays for cataracts increased considerably (0.31; 95 % CI: 0.22, 0.40). Significant ERR/Gy of external gamma-rays for senile cataract was revealed in both male and female workers of the study cohort, however the variations between the sexes were insignificant (p = 0.09). ERR/Gy of external gamma-rays for senile cataract was significant in all age groups except for workers under 40 years, but the differences among the age groups were insignificant (p > 0.5).
Conclusion: Risk of senile cataract incidence in the cohort of Mayak PA workers, occupationally exposed to radiation over prolonged periods, was significantly associated with dose from external gamma-rays.
Key words: risk, incidence, senile cataracts, external radiation, staff of Mayak PA, prolonged exposure
REFERENCES
- Otake M, Schull WJ. A review of forty-five years study of Hiroshima and Nagasaki atomic bomb survivors Radiation cataract. J Radiat Res. 1991;32 Suppl:283-93.
- Gus’kova AK, Baisogolov GD. Radiation disease of human. Moscow: Medicina; 1971. 384 p. Russian.
- Recommendations of the International Commission on Radiological Protection. ICRP Publication 26. Ann ICRP. 1977;1(3).
- Hamada N, Fujimichi Y. Classification of radiation effects for dose limitation purposes: history, current situation and future prospects. J Radiat Res; 2014;55(4):629-40.
- Statement on tissue reactions/Early and late effects of radiation in normal tissues and organs - threshold doses for tissue reactions in a radiation protection context. ICRP Publication 118. Ann ICRP.2012;41(1/2).
- Hamada N, Fujimichi Y, Iwasaki T, et al. Emerging issues in radiogenic cataracts and cardiovascular disease. J Radiat Res. 2014;55(5):831-46.
- ICD-9 guidelines for coding diseases, injuries and causes of death/revision 1975. Geneva, Switzerland: WHO; 1980.
- Azizova TV, Tepljakov II, Grigor’eva ES, et al. “Clinic” Medical Dosimetric Database for Mayak PA Personnel and Its Families. Med. Radiology and Radiation Safety. 2009;54(5):26-35. Russian.
- Khokhryakov VV, Khokhryakov VF, Suslova KG, et al. Mayak Worker Dosimetry System 2008 (MWDS-2008): Assessment of internal alpha-dose from measurement results of plutonium activity in urine. Health Phys. 2013;104(4):366-78.
- Preston D, Lubin J, Pierce D, et al. EPICURE Users Guide. Seattle, WA: Hirosoft; 1993.
- Bragin EV, Azizova TV, Bannikova MV. Cataract incidence in the cohort of occupationally exposed workers. Oftal’mologia. 2016;13(2):115-21. Russian.
- Bragin EV, Azizova TV, Bannikova MV. Risk of senile cataract among nuclear industry workers. Ophthalmology. 2017;33(2):57-63. Russian.
- Neriishi K, Nakashima E, Akahoshi M, et al. Radiation dose and cataract surgery incidence in atomic bomb survivors, 1986-2005. Radiology. 2012;265(1):167-74.
- Neriishi K, Nakashima E, Minamoto A, et al. Postoperative cataract cases among atomic bomb survivors, radiation dose response and threshold. Radiat Res. 2007;168(4):404-8.
- Nakashima E, Neriishi K, Minamoto A. A reanalysis of atomic-bomb cataract data, 2000-2002, a threshold analysis. Health Phys. 2006;90(2):154-60.
- Worgul BV, Kundiyev YI, Sergiyenko NM, et al. Cataracts among Chernobyl clean-up workers, implications regarding permissible eye exposures. Radiat Res. 2007;167(2):233-43.
- Chodick G, Bekiroglu N, Hauptmann M, et al. Risk of cataract after exposure to low doses of ionizing radiation: a 20-year prospective cohort study among US radiologic technologists. Amer J Epidemiol. 2008;168(6):620-31.
- Guidance on Radiation Dose Limits for the Lens of the Eye. NCRP Commentary No. 26. National Council on Radiation Protection and Measurements. Bethesda, MD: NCRP; 2016.
For citation: Azizova TV, Bragin EV, Hamada N, Bannikova MV. Risk Assessment of Senile Cataract Incidence in a Cohort of Nuclear Workers of Mayak Production Association. Medical Radiology and Radiation Safety. 2018;63(4):15-21. Russian. DOI: 10.12737/article_5b83b0430902e8.35861647
PDF (RUS) Full-text article (in Russian)