Medical Radiology and Radiation Safety. 2025. Vol. 70. № 5

DOI:10.33266/1024-6177-2025-70-5-5-10

S.M. Rodneva, L.P. Sycheva, D.V. Guryev

Cytogenetic Effects In Mammalian Cells Exposed To Tritium Compounds

A.I. Burnazyan Federal Medical Biophysical Center, Moscow, Russia

Contact person: Sofya Mikhailovna Rodneva, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

 

CONTENT

 

Introduction

1. Induction of chromosomal aberrations in stimulated and unstimulated human peripheral blood lymphocytes by exposure to tritiated water (HTO);

2. Induction of micronuclei in peripheral blood lymphocytes when exposed to tritium

3. Assessment of the relative biological effectiveness of tritium in cytogenetic studies 

Conclusion

Keywords: tritium, chromosomal aberrations, lymphocytes, micronuclei, RBE

For citation: Rodneva SM, Sycheva LP, Guryev DV. Cytogenetic Effects In Mammalian Cells Exposed To Tritium Compounds. Medical Radiology and Radiation Safety. 2025;70(5):5–10. (In Russian). DOI:10.33266/1024-6177-2025-70-5-5-10

 

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Conflict of interest. The authors declare no conflict of interest.

Financing. The study was carried out within the framework of the state contract, No. H.2z.217.08.24.2199, research topic «Zalp».

Contribution. Article was prepared with equal participation of the authors.

Article received: 20.05.2025. Accepted for publication: 25.06.2025.