Medical Radiology and Radiation Safety. 2026. Vol. 71. № 4
DOI:10.33266/1024-6177-2026-71-4-98-102
R.V. Sargar1, I.A. Kurnikova1, V.A. Kokorin1, I.O. Tomashevsky2, M.O. Shatalova2
STUDY OF THYROID FUNCTION PARAMETERS IN NORMAL AND VARIOUS PATHOLOGICAL CONDITIONS USING X-RAY COMPUTED TOMOGRAPHY
1 Patrice Lumumba Peoples’ Friendship University of Russia, Moscow, Russia
2 Private Healthcare Institution “Central Clinical Hospital “RZhD-Medicine”, Moscow, Russia
Contact person: M.O. Shatalova, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
ABSTRACT
Purpose: To assess the effect of occupational hazards on the state of the gastric mucosa in the workers of the radiochemical plant of the Mayak Production Association (PA).
Material and methods: Current study includes 62 workers of the Mayak PA radiochemical plant, with a mean age at the date of investigation of 52.7±1.0 years, who were in constant contact with occupational hazards (ionizing radiation and chemical toxins). A laboratory study was performed using GastroPanel test-systems produced by BIOHIT OYJ (Finland). Analysis of the data obtained was carried out using Microsoft Excel software.
Results: Pathological changes in the gastric mucosa identified using a serological method were found in 84% of the group members, for 34% these changes were diagnosed for the first time. The prevalence of Helicobacter pylori infection in the study group (82%) corresponded to the rates for this age group in the Ural region. The incidence of non-atrophic pathology among the workers in the study group (64.5%) was not higher than the rates in the comparison group 9 the workers of city organizations not exposed to occupational hazards). The incidence of pre-cancer stomach diseases (atrophic gastritis) at the radiochemical plant (19.3%) was 4 times higher than in the comparison group (4.8%) (OR 4.8; 95%CI 1.8‒12.8). The overall frequency of gastric pathologies in the group with external exposure doses > 100 mSv was statistically significantly 1.5 times higher compared to the group with exposure doses ≤ 100 mSv (p=0.023).
Conclusion: We have demonstrated that serological method is sufficiently effective to diagnose pre-carcinogenic gastropathology even with no clinical symptoms. The increase of frequency of the gastric mucosa pathology in persons with occupational contact to industrial chemical hazards: increased frequency of gastropathology in workers contacting to inorganic compounds or mixture of inorganic/organic compounds. An increased frequency of gastropathology in workers with cumulative doses of external γ-exposure exceeding 100 mSv had also been demonstrated. The data obtained suggest that differences in the incidence of gastropathology may be related to the impact of occupational risk factors. Due to their combined influence, it is impossible to link changes in the incidence of gastropathology in workers to the impact of a single occupational factor.
Keywords: thyroid function, thyroid iodine content, CT, density
For citation: Sargar RV, Kurnikova IA, Kokorin VA, Tomashevsky IO, Shatalova MO. Study of Thyroid Function Parameters in Normal and Various Pathological Conditions using X-ray Computed Tomography. Medical Radiology and Radiation Safety. 2026;71(4):98– 102. DOI:10.33266/1024-6177-2026-71-4-98-102
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PDF (RUS) Full-text article (in Russian)
Conflict of interest.The authors declare no conflict of interest.
Financing. The study had no sponsorship.
Contribution. Article was prepared with equal participation of the authors.
Article received: 20.03.2026. Accepted for publication: 25.04.2026.