SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

Medical Radiology and Radiation Safety. 2019. Vol. 64. No. 4. P. 64–75

DOI: 10.12737/1024-6177-2019-64-4-64-75

O.K. Kurpeshev1, J. Van der Zee2, M. Cavagnaro3

Hyperthermia for Deep Seated Tumours – Possibilities of Heating with Capacitive Devices

1. Siberian Scientific Research Institute of Hyperthermia, Novosibirsk region, Iskitim-5, Russia;
2. Erasmus Medical Centre, University Medical Center Rotterdam, Rotterdam, Netherlands;
3. Sapienza University, Rome, Italy

O.K. Kurpeshev – PhD, MD, consultant;
J. Van der Zee – PhD, MD, member of European Society for Hyperthermic Oncology (ESHO);
M. Cavagnaro – Prof., PhD, Member of the Societies of the Institute of Electrical and Electronics Engineers (IEEE), the European Society for Hyperthermic Oncology (ESHO) and the European Association of BioElectromagnetics (EBEA)

Abstract

The review examines the general principles of capacitive electromagnetic hyperthermia (EMHT), the distribution of electromagnetic energy in various experimental models and in patients’ tumors, the design features of applicators from various capacitive hyperthermic systems and their role in achieving hyperthermic mode in tumors of deep localization. In classical capacitive EMHT, the main obstacle in achieving the required temperature in such tumors is overheating of the subcutaneous fatty tissue under the electrodes. For some capacitive hyperthermic systems, the heating of adipose tissues is enhanced due to the fact that the applicator design does not conform to certain technical requirements. In capacitive EMHT at frequencies of 8–13.56 MHz, obtaining the minimum hyperthermic mode is possible with output powers of 500–800 W, maximum – 1000–1200 W and above.

The results of the use of various hyperthermic capacitive systems in patients with malignant tumors of internal organs are analyzed.

Key words: radiation therapy, chemotherapy, thermoradiotherapy, thermochemotherapy, thermochemoradiation therapy, electromagnetic fields, hyperthermia, capacitive devices

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For citation: Kurpeshev OK, Van der Zee J, Cavagnaro M. Hyperthermia for Deep Seated Tumours – Possibilities of Heating with Capacitive Devices. Medical Radiology and Radiation Safety. 2019;64(4):64–75. (English and Russian).

DOI: 10.12737/1024-6177-2019-64-4-64-75

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