Medical Radiology and Radiation Safety. 2016. Vol. 61. No. 5. P. 80-84


E.V. Dorokhov1, E.D. Isaguliyan2, P.A. Isaev3, D.Yu. Siomin3, V.V. Polkin3

Possibilities of Spinal Cord Stimulation for Radiation-Induced Brachial Plexopathy

1. I.M. Sechenov First Moscow State Medical University, Moscow, Russia; 2. N.N. Burdenko Neurosurgery Institute, Moscow, Russia; 3. A.F. Tsyb Medical Radiological Research Centre, Obninsk, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.


According to current data in modern oncology, delayed radiation-induced brachial plexopathies are rare complications of radial therapy of malignant tumors. However, in Russian clinical practice these complications appear not so rarely for a number of reasons, including obsolescent equipment usage. Unfortunately, full functional rehabilitation for such patients is almost impossible due to irreversibility of pathological process. That is why the main problem in the treatment of radiation-induced plexopathy is chronic pain management that is rather limited in remedies. The article is aimed to demonstrate and analyze the clinical case of high efficacy of spinal cord stimulation in the treatment of chronic medically resistant pain in a female patient with radiation-induced plexopathy.

Key words: radiation therapy, plexopathia, neurostimulation


  1. Gosk J., Rutowski R., Reichert P., Rabczynski J. Radiation-induced brachial plexus neuropathy -aetiopathogenesis, risk factors, differential diagnostics, symptoms and treatment. Folia Neuropathologica. 2007. Vol. 45. No 1. P. 26-30.
  2. Delanian S., Lefaix J.L. Pradat P.F. Radiation-induced neuropathy in cancer survivors. Radiother. Oncol. 2012. Vol. 105. No. 3. P. 273-282.
  3. Pradat P.F., Delanian S. Late radiation injury to peripheral nerves. Handbook of Clinical Neurology. Vol. 115. P. 743-758.
  4. Pasov V.V. Mestnye luchevye povrezhdeniya posle kombinirovannogo lecheniya raka molochnoi zhelezy. Chastota razvitiya i metody korrektsii. Dis. d-ra. med. nauk. 2000. Available from: (In Russ.).
  5. Pasov V.V., Bardychev M.S. Luchevye povrezhdeniya plechevogo spleteniya ili metastazy. Problemy diagnostiki. Medical Radiology and Radiation Safety. 1996. Vol. 41. No. 6. P. 64-66. (In Russ.).
  6. Lederman R.J., Wilbourn A.J. Brachial plexopathy: recurrent cancer or radiation?. Neurology. 1984. Vol. 34. No. 10. P. 1331-1335.
  7. Roth G., Magistris M.R., Le Fort D. et al. Postradiation brachial plexopathy. Persistent conduction block. Myokymic discharges and cramps.. Revue Neurologique. 1988. Vol. 144. No. 3. P. 173-180.
  8. Harper C.M., Thomas J.E., Cascino T.L., Litchy W.J. Distinction between neoplastic and radiation-induced brachial plexopathy, with emphasis on the role of EMG. Neurology. 1989. Vol. 39. No. 4. P. 502-506.
  9. Rubin D.I. Diseases of the plexus. CONTINUUM: Lifelong Learning in Neurology. Vol. 3. No. 14. P. 156-179.
  10. Olsen N.K, Pfeiffer P., Johannsen L. et al. Radiationinduced brachial plexopathy: neurological follow-up in 161 recurrence-free breast cancer patients. Internat. J. Radiat. Oncol. Biol. Phys. 1993. Vol. 26. No. 1. P. 43-49.
  11. Wolter T. Spinal cord stimulation for neuropathic pain: current perspectives. J. Pain Res. 2014. Vol. 18. No. 7. P. 651-653.
  12. Cruccu G., Aziz T.Z, Garcia-Larrea L. et al. EFNS guidelines on neurostimu. Eur. J. Neurol. 2007. 14. No. 9. P. 952-970.

For citation: Dorokhov EV, Isaguliyan ED, Isaev PA, Siomin DYu, Polkin VV. Possibilities of Spinal Cord Stimulation for Radiation-Induced Brachial Plexopath. Medical Radiology and Radiation Safety. 2016;61(5):80-4. Russian.

PDF (RUS) Full-text article (in Russian)