Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 42-46
RADIATION THERAPY
K.G. Moskalik, A.P. Kozlov
Clinical and Morphological Factors in Evaluation of Efficacy of Facial Carcinoma Treatment by High-energy Pulsed Neodymium Laser
N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Purpose: This trial has estimated an influence of clinicalmorphological factors of facial carcinomas on the results of its treatment by means of Neodymium laser radiation.
Material and methods: The radiation of high-energy mono-pulsed laser (λ = 1060 nm) was used for treatment of 2,805 patients with 2,940 morphologically confirmed facial carcinoma of stages T1–2N0M0. Out of them, there were 2,845 primary basal cell carcinoma (BCC) and 95 squamous cells carcinoma (SCC). The patients were followed-up from 1 to 13 years.
Results: Overall, the recurrence rate after laser radiation was 2.0 % of all irradiated tumours. The highest rate of recurrences was found in SCC (5.3 %) if compared to BCC (1.9 %). Also high rate of recurrences was detected in infiltrative-ulcerative (4.5 %) tumours as well as in lesions located in nasolabial area (3.2 %). Rate of recurrences has increased along with the enlarging stage of disease.
Conclusion: Neodymium laser radiation is a practical and useful method for treatment of facial carcinomas, which results depend on tumour morphology, their clinical characteristic, localization and stage of disease.
Key words: facial carcinoma, neodymium laser, non-ionization radiation