JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues

CONTENTS № 3 - 2024

 View or download the full issue in PDF (Russian)

RADIATION BIOLOGY 

5

Evaluation of the Effectiveness of The Use of Decellularized Human Amniotic Membrane in Combination with Cell Therapy for Local Radiation Injuries

Rastorgueva A.A., Astrelina T.A., Brunchukov V.A., Kobzeva I.V.,
Suchkova Yu.B., Nikitina V.A., Lishchuk S.V., Dubova E.A., Pavlov K.A.,
Malivanova T.F., Usupzhanova D.Yu., Mikhadarkina O.G., Kobzev A.D.,
Bulygina V.I., Samoilov A.S.

13

Link Between Cellular Senescence and Changes in The Number and Size of Phosphorylated Histone H2AX Foci in Irradiated Human Fibroblasts

Osipov A.A., Chigasova A.K., Yashkina E.I., Ignatov M.A., Vorobyеva N.Yu., Osipov A.N. 

19

Study of Clinical, Hematologic and Immunologic Parameters in Assessing the Anti-Radiation Efficacy of the Therapeutic Agent Based on the Microorganism Fusobacterium Necrophorum

Gaynutdinov T.R., Ryzhkin S.A., Vagin K.N., Trizna E.Yu., Ohrimenko S.E. 

 

26

Fluorimetric Evaluation of the Effect of Riboxin, Copper Chlorophyllin, Trolox and the Soluble form of Indralin on the Growth Properties of A549 Cells in Culture

Romodin L.A., Yashkina E.I., Moskovskij A.A.

RADIATION MEDICINE

35

The Mitochondrial 18 kDa Translocator Protein as a Biomarker of Radiation-Induced Neuroinflammatory

Rodina A.V.

RADIATION EPIDEMIOLOGY

46

Analysis of the Influence of Radiation Exposure on Multimorbidity Among Liquidators of the Consequences of the Accident at the Chernobyl Nuclear Power Plant

Korelo A.M., Maksioutov M.A., Chekin S.Yu., Kochergina E.V.,
Lashkova O.E.

53

Evaluation of the Radiation Risk of Death from Cardiovascular Diseases among the Liquidators Involved in the Cleaning up of the Consequences of the Chernobyl Accident – Workers in the Nuclear Industry Sector

Tukov A.R., Shafransky I.L., Koterov A.N., Ziyatdinov M.N., Prokhorova O.N., Mikhaylenko A.M.

57

The Mortality Risk from Main Pathologies Due to Passive Smoking is not Achieved by the Overwhelming Majority of Nuclear Workers in All Periods of Employment

Koterov A.N., Ushenkova L.N., Wainson A.A., Dibirgadzhiev I.G.,
Kalinina M.V., Bushmanov A.Yu.

RADIATION 
THERAPY

68

Clinical Audits Methodology of the Radiotherapy Departments in Russian Federation Based on IAEA Audits Principles

Chernykh M.V., Krylova T.A.

NUCLEAR MEDICINE

72

Assessment of Acute Toxicity of the 99mTc(CO)3-(HE)3-DARPinG3 in Breast Cancer Patients

Bragina O.D., Borodina M.E., Chernov V.I., Deyev S.M., Vostrikova M.A., Romanova A.A.

77

The Importance of SPECT/CT in Simultaneous Assessment of Calcinosis of Coronary Arteries, Perfusion and Contractile Function of the Myocardium among Men’s with Coronary Heart Disease

Tomashevsky I.O., Kornikova O.S. 

RADIATION PHYSICS, ENGINEERING AND DOSIMETRY 

81

Novel Approach Using Transfer Deep Learning for Brain Tumor Prediction

Muaayed F. Al-Rawi, Izz K. Abboud, and Nasir A. Al-Awad.

ANNIVERSARY

86

Promising aspects of biomedical science and practice - for the 100th anniversary of A.K. Guskova: parting words to doctors and scientists

Metlyaeva N.A.

89

In Memory of Radiotoxicologist Yuri Alexandrovich Klassovsky. 100th Anniversary of his Birth on 01/15/1924–04/27/1982

Ivanov I.V., Vyalykh V.N.

   

  

 

CONTENTS № 2 - 2024

 View or download the full issue in PDF (Russian)

RADIATION BIOLOGY 

5

Modeling of Radiation Damage on the Background of Pasteurellosis Infection of the Organism

Gaynutdinov T.R., Vagin K.N., Ryzhkin S.A., Kalimullin F.H., Ohrimenko S.E.

12

Mechanisms of Mitochondrial Influence on Tumor Radioresistivity

Rozenberg J.M., Maximov V.V., Kuzmin D.V., Leonov SV..  

18

Comparison of the Radioprotective Properties of Riboxin (Inosine) and Indralin with Prophylactic Administration at Dosages of 100 mg/кg According to the Survival Criterion of Irradiated Mice

Romodin L.A., Nikitenko O.V., Bychkova T.M., Zrilova Yu.A.,
Rodionova E.D., Bocharov D.A.

RADIATION SAFETY 

24

Development of the Legal Framework in the Field of Radiation Safety

Samoylov A.S., Kochetkov O.A., Klochkov V.N., Barchukov V.G.,
Shinkarev S.M.

30

Scientific and Methodological Support of Health and Epidemiological Supervision during the Remediation of Nuclear Legacy Facilities and Sites and Tasks for the Future

Shandala N.K., Kiselev S.M., Seregin V.A., Filonova A..A, Isaev D.V. 

RADIATION EPIDEMIOLOGY

38

Dose Dependence for Mortality from Circulatory Diseases in Nuclear Workers (Systematic Review and Pooled Analysis): Lack of Low Doses Effect and Confirmation of Unscear and Icrp Threshold at 0.5 Gy

Koterov A.N., Ushenkova L.N., Wainson A.A., Dibirgadzhiev I.G.,
Kalinina M., Bushmanov A.Yu.

RADIATION DIAGNOSTICS

49

The Importance of Radiation Methods in the Diagnosis of Coronary Heart Disease in a Specific Patient

Tomashevsky I.O., Kornikova O.S.

NUCLEAR MEDICINE

53

Nuclear Physics Medical Elementology as a Section of Medical Radiology

Zaichick V., Kolotov V.

RADIATION PHYSICS, ENGINEERING AND DOSIMETRY 

65

Theoretical Analysis of the Radiation Quality and the Relative Biological Efficiency of Tritium

Rodneva S.M., Guryev D.V. 

73

Experience in Developing Radiation Sources for Personalized Brachytherapy Based on Titanium Alloys

Chuvilin D.Yu., Skobelin I.I., Kurochkin A.V., Makoveeva K.A.,
Strepetov A.N., Karalkin P.A., Karalkina M.A., Reshetov I.V. 

REVIEW

81

Review of the Monograph by Yu.A. Klassovsky «The Effect of External and Internal Irradiation in the Conditions of Formation of Radioactive Traces of Nuclear Explosions. Questions of Etiology and Pathogenesis»

Ushakov I.B.

CHRONICLE

83

Angelina Konstantinovna Guskova (for the 100th Anniversary of her Birth)

Efimova I.L.

   

  

CONTENTS № 6 - 2023

View or download the full issue in PDF (Russian)

5

In Memory of Leonid Andreevich Ilyin

RADIATION
BIOLOGY

8

The Significance of Corticosteroid Binding to Plasma Proteins in the Mechanism of the Effect of the Radioprotector Rs-11 on the Function of the Adrenal Cortex in Acute Radiation Sickness

Omelchuk N.N.

RADIATION
SAFETY 

13

Unified Information System of The URCRM of FMBA of Russia

Nikiforov V.S., Krivoshchapov V.A., Startsev N.V.

20

Comparison of Radiation and Chemical Toxicity of Uranium Compounds on The Basis of Calculation by New ICRP Biokinetic Models

Molokanov A.A., Potsyapun N.P., Maksimova E.Yu., Kvacheva Yu.E.

27

Effective Doses of Children During X-Ray Diagnostic Examinations: A Literary Review

Shatskiy I.G., Druzhinina P.S., Kapyrina Yu.N., Osipov M.V.

42

Health Effects of  Onboard Radiation Accidents in the Soviet Nuclear Submarines

Ilyin L.A. , Kochetkov O.A., Barabanova A.V., Barchukov V.G.

RADIATION MEDICINE

49

Analysis of -Segment Diversity of T-Cell Receptor in Residents of the Techa Riverside Villages Chronically Exposed to Radiation in the Long-Term Period

Kotikova A.I., Blinova E.A., Akleyev A.V.

55

Effect of Radiation and Non-Radiation Factors on the ТBX21 Concentration in lysates of the Mitogen-Stimulated Mononuclear Cells

Kodintseva Е.А., Akleyev А.А.

RADIATION EPIDEMIOLOGY

60

Diabetes Mellitus Incidence and the Risk of its Occurrence in Liquidators of the CHNPP Accident Consequences including Nuclear Industry Workers

Tukov A.R., Shafransky I.L., Prokhorova O.N., Mikhailenko A.M.,
Ziyatdinov M.N.

RADIATION DIAGNOSTICS

67

Cryptogenic Organizing Pneumonia (Clinical Case Report, Literature Review)

Sheikh Zh.V., Shvayko S.N., Leonova L.G., Tarachkova E.V.,
Bogdanova E.I., Stepanchenko E.S.

73

Modern Possibilities of Imaging Diagnosis Methods in Assessing the Severity of Fatty Hepatosis in Non-Alcoholic Fatty Liver Disease (Clinical Case)

Matkevich E.I., Bashkov A.N., Ionova E.A., Veselkova A.U., Rudakov V.S., Parinov O.V., Kapustin V.V.

80

The Apparent Diffusion Coefficient in the Diagnosis of Metastatic Lesions of Skeletal Bones

Prokhorov S.N., Kochergina N.V., Ryzhkov A.D., Krylov A.S., Bludov A.B.

RADIATION

THERAPY

86

Combined Treatment of Salivary Gland Cancer Patients with the Use of High-Let Radiation

Gribova O.V., Startseva Zh.A., Choynzonov E.L., Novikov V.A.,
Ryabova A.I., Shtin V.I.

92

Features of the Systemic Response to Adjuvant Radiation Therapy in Carriers of Polymorphism -308(G/A)TNF in Breast Cancer Patients

Malivanova T.F., Astrelina T.A., Kobzeva I.V., Nikitina V.A., Suchkova Y.B., Golovkova A.I., Ostashkin A.S., Usupzhanova D.Y., Brunchukov V.A., Rastorgueva A.A., Dobrovolskaya E.I., Kirilchev A.P., Sukhova M.Yu., Mikhadarkina O.G., Sokolova N.V., Samoilov A.S. 

99

Brachytherapy of Malignant Neoplasms of the Cervix Uteri: Current Status of the Problem (Literature Review)

Zavyalov A.A., Solodova A.N., Tyryshkin A.I., Kryakvina E.V.

NUCLEAR

MEDICINE

106

Development of Software Tools Based on Clinical Data and Phantom Studies for Mathematical Simulation Modeling to Assess Brain Perfusion and Improve Image Quality During SPECT/CT with 99mTc-GMPAO

Denisova N.V., Nesterova A.V., Minin S.M., Anashbayev Zh.Zh.,
Krasilnikov S.E., Ussov W.Yu.

RADIATION PHYSICS, TECHNIQUE AND DOSIMETRY

118

Comparison of Photon and Neutron Radiation Dosimetric Systems Used in Organizations of Rosatom State Corporation for Control in A Planned Exposure Situation

Kochetkov O.A., Tarasova E.Yu., Shinkarev S.M., Rumyantsev E.A.

   

  

CONTENTS № 1 - 2024

View or download the full issue in PDF (Russian)

GENERAL
ISSUES

5

Results of the 70-th Session of the United Nations Scientific Committee on the Effects of the Atomic Radiation (UNSCEAR) (Vienna, 19–23 June, 2023)

Akleyev A.V., Azizova T.V., Ivanov S.A., Kiselev S.M., Takhauov R.M., Fesenko S.V., Shinkarev S.M.

RADIATION BIOLOGY 

15

Post-Radiation Changes in The Number of Phosphorylated H2ax and Atm Protein Foci in Low Dose X-Ray Irradiated Human Mesenchymal Stem Cells

Chigasova A.K., Pustovalova M.V., Osipov A.A., Korneva S.A., Eremin P.S., Yashkina E.I.,
Ignatov M.A., Fedotov Yu.A., Vorobyeva N.Yu., Osipov A.N.

20

Comparative Assessment of the Effect of Local Proton Radiation with a Dose of 30 Gy in BALB/c and C57BL/6 Mice

Anikina V.A., Sorokina S.S., Shemyakov A.E., Zamyatina E.A., Popova N.R.

28

Fluorimetric Evaluation of the Effect of Malic, Succinic and Ascorbic Acids on the Growth Properties of A549 Cells in Culture

Romodin L.A., Yashkina E.I., Moskovskij A.A.

RADIATION SAFETY  

33

Digital Twin of Worker of  Nuclear Facility at the Stage of Pre-Shift Control

Baranov L.I., Tsarev A.N., Torubarov F.S., Kretov A.S., Petrova V.V.,
Vasilyev E.V., Dumansky S.M., Tikhonova O.A., Bulanova T.M., Kalinina M.V., Shulepov P.A., Dibirgadzhiyev I.,
Samoilov A.S.

41

Radio-Ecological Situation in the Area of the Uranium Legacy Site – Stepnaya Mine (Kalmykia)

Titov A.V., Belskikh Iu.S., Isaev D.V., Shandala N.K., Doroneva T.A., Bogdanov I.I., Semenova M.P., Shitova A.A., Burthev S.L. 

50

Assessment of the Radiation Situation during Short-Term Flights to the Moon

Ivanov I.V., Burmistrov V.I., Matkevich E.I.

RADIATION MEDICINE

61

Comparative Retrospective Analysis of the Results of Cytogenetic Studies of Employees of the Object of Use of Ionizing Radiation

Vishnevskaya T.V., Isubakova D.S., Tsyplenkova M.Yu., Tsymbal O.S.,
Milto I.V., Takhauov R.M.

67

Multiple Primary Malignant Tumors in Workers Chronically Exposed to Ionizing Radiation

Zhuntova G.V., Azizova T.V., Bannikova M.V.

RADIATION EPIDEMIOLOGY

73

The Sublimate Production Cohort of the Siberian Chemical Plant (Dosimetric Characteristics)

Kalinkin D.E., Milto I.V., Takhauov A.R., Takhauova L.R., Samoilova Y.A., Gorina G.V., Litvinova O.V., Takhauov R.M. 

RADIATION THERAPY 

77

Water Bolus Utilization for the Radiation Therapy of Patients with Isolated Superficial Lesions of Cutaneous T-Cell Lymphoma

Shkuratov A., Golub S., Kirpichev Y., Moiseev A., Korovin I., Kryaneva A.

NUCLEAR MEDICINE

83

Own Experience of using the Radiopharmaceutical 99mTc-sentiskan in Visualization of Sentinel Lymph Nodes in Patients with Breast Cancer

Tamrazov R.I., Khusnutdinov R.D., Alekhin E.N., Averina N.V.,
Pyshkina Yu.S., Pashkov D.А.

88

The Impotance of SPECT/CT in Simultaneous Assessment of Calcinosis of Coronary Arteries, Perfusion and Contractile Function of the Myocardium among Females with Coronary Heart Disease

Tomashevsky I.O., Kornikova O.S.

RADIATION PHYSICS, ENGINEERING AND DOSIMETRY 

92

Study of 239Pu Microdistribution in Liver of Mayak Workers Using Neutron-Activated Measurement Method

Sypko S.A., Bobov G.N., Vvedensky V.E., Nazarenkova A.V.

   

  

CONTENTS № 5 - 2023

View or download the full issue in PDF (Russian)

RADIATION
BIOLOGY

5

Protective Properties of Compound Aicar in Vivo Exposed to Radiation

Abdullaev S.A., Saleeva D.V., Dushenko M.V., Raeva N.F., Abdullaeva А.I., Zasukhina G.D., Osipov A.N.

11

Late Effects of γ, n-Irradiation of Mice: Shortening of Telomeres and Tumors Development

Moskaleva E.Yu., Vysotskaya O.V., Zhorova E.S., Shaposhnikova D.A.,
Saprykin V.P., Cheshigin I.V., Smirnova O.D., Zhirnik A.S.

RADIATION

SAFETY

19

Integration of Icrp Oir Models Into the iDose 2 Dosimetry System

Vostrotin V.V.

28

Radiation Situation Around Commissioning Mine No. 6 of Pjsc ‘Priargunskiy Mining and Chemical Production Association’

Shandala N.K., Gushchina I.V., Titov A.V., Belskikh I.S., Seregin V.А., Doroneva T.A., Isaev D.V., Starinskiy V.G., Shitova A.A. 

34

When the Factor of Crystallized Intelligence Can Be a Professionally “Undesirable” Personal Quality of Operators

Kosenkov A.A.

38

To the Question of the Interpretation of the Terms “Dose Limit” and “Radiation Accident”
in the Development of New Norms of Radiation Safety

Ryzhov S.A., Narkevich B.Ya., Vodovatov A.V.

RADIATION MEDICINE

44

State of Bone Marrow Hematopoiesis in Chronic Radiation Disease Patients, Irradiated with Different Dose Rates

Galstian I.A., Bushmanov A.Yu., Metlyaeva N.A., Konchalovsky M.V.,
Nugis V.Yu., Torubarov F.S., Shcherbatykh O.V., Zvereva Z.F., Yunanova L.A.

50

Comparative Characteristics of Eeg Frequency Bands and Cerebral Energy Exchange
at a Low Level of Psychophysiological Adaptation in Employees of Nuclear Hazardous Enterprises and Productions

Zvereva Z.F., Torubarov F.S., Vanchakova N.P., Lukyanova S.N.,
Miroshnik E.V., Denisova E.A.

RADIATION EPIDEMIOLOGY

60

Individualized Approach to the Formation of High Cancer Risk Groups Based on the Assessment of Immunological Indicators in Chronically Exposed People

Kodintseva E.A., Akleyev A.А.

65

Risk of Thyroid Diseases Associated with Iodine Deficiency of Liquidators of the Consequences of the Accident at the Chernobyl NPP ‒ Employees of Nuclear Industry Enterprises

Tukov A.R., Shafransky I.L., Prohorova O.N., Mikhaylenko A.M.,
Ziyatdinov M.N.

RADIATION

THERAPY

71

Ten-Year Results of Complex Treatment of Patients with Primary Local Advanced Breast Cancer

Velikaya V.V., Startseva Zh.A., Goldberg V.E., Popova N.O.

77

Thermoradiochemotherapy in the Combined Treatment of Rectal Cancer

Plaskeeva D.A., Konovalov A.I., Startseva Zh.A., Afanasyev S.G.

NUCLEAR

MEDICINE

82

Variants of Sentinel Lymph Node Research Protocols in Breast Cancer

Azimova E.K., Abdulloeva Sh.Sh., Usov F.N., Zikiryakhodzhaev A.D.,
Egina E.I.

 

88

Radionuclide Diagnosis of Sentinel Lymph Nodes in Breast cancer with a Radiopharmaceutical Based on Technetium-99m Labeled Gamma Aluminum Oxide

Medvedeva A.A., Rуbina A.N., Zeltchan R.V., Bragina O.D.,
Doroshenko A.V., Garbukov E.Iu., Tarabanovskaya N.A., Tashireva L.A., Chernov V.I.

96

SPECT/CT with 99mTc-technetryl in Staging, Planning of External Radiotherapy and Follow-up in Lung Cancer: a Clinical Case and Case – Addressed Review of Literature

Minin S.M., Anashbayev Zh.Zh., Samoylova E.A., Zheravin A.A.,
Ussov W.Yu., Krasilnikov S.E., Cherniavsky A.M.

   

  

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