CONTENTS № 4 - 2025

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RADIATION 
BIOLOGY

5

Investigation of the Combined Effect of Protons and the Chemotherapy Drug Doxorubicin on the Expression of BIRC5 (Survivin) Genes and PMAIP1 (Noxa) in MCF-7 Cells

Melnikova A.A., Afonin A.A., Komarova L.N., Saburov V.O.

10

Sensitivity to Chemoradiation Effects of Human Non-Small Cell Lung Cancer Cells Surviving Fractionated Irradiation with a Total Dose of 20 Gy

Molodtsova D.V., Kotenkova E.A., Polishchuk E.K., Osipov A.A.,
Guryev D.V., Chigasova A.K., Vorobyeva N.Yu., Osipov A.N. 

16

Study of Proton Beam Influence on the Growth Dynamics and Viability of 3D Cell Spheroids Formed From 4T1 Carcinoma Cells

Mysina E.A., Popova N.R., Shemyakov A.E., Savintseva I.V.,
Chukavin N.N., Popov A.L.

21

Experimental Study of Radioprotective Efficiency of Indralin in Outbred Mice ICR (CD-1) SPF-Category Irradiation with Pulsed Bremsstrahlung X-Rays in Ultra-High Dose Rate (FLASH) Mode 

Soloviev V.Yu., Bushmanov A.Yu., Ushakov I.B., Nikitenko O.V.,
Bychkova T.M., Ivanov A.A., Fedotov Yu.A., Ganzhelyuk M.L.,
Mershin L.Yu., Kretov A.S., Gimadova T.I., Alekseev Dmitrij M.,
Alekseev Daniil M., Osipov A.N.

25

The Contribution of Effector Cells of the Innate and Adaptive Immunity to the Pathogenesis of Radiation-Induced Carcinogenesis. Review (Part 1)

Kodintseva E.A., Akleyev A.А.

33

Evaluation of the Use of a Modified Hydrogel in the Treatment of Local Radiation-Induced Skin Injures of Laboratory Animals

Merkulov M.V., Astrelina T.A., Usupzhanova D.Yu., Brunchukov V.A., Kobzeva I.V., Suchkova Yu.B., Iashin N.P., Mikhadarkina O.G., Nikitina V.A., Malivanova T.F., Dubova E.A., Lishchuk S.V., Pavlov K.A., Serova O.F..

RADIATION 
SAFETY

39

The Digital Twin and the Digital Profile as the Basis for the Collection and Analysis of Medical Data

Baranov L.I., Bushmanov A.Yu., Vasilev Е.V., Tsarev A.N.,
Dumansky S.M., Dibirgadzhiyev I.G., Bulanova T.M., Popova E.V.,
Smirnov Yu.E., Kalinina M.V.

46

Using Artificial Intelligence Technologies for Radiation Protection during Decommissioning of Radiation and Nuclear Facilities

Barchukov V.G., Bolotov A.A., Zhirnov Y.N., Samoylov A.S., 
Shinkarev S.M., Ushakov I.B., Tesnov I.K., Galuzin A.S., 
Kudinova D.A., Lizunov V.U.

RADIATION EPIDEMIOLOGY

55

Assessment of Radiation Risks of Digestive System Diseases among Chernobyl Liquidators, Considering the Influence of Other Diseases Identified in Them During the Follow-up Period

Chekin S.Yu., Gorski A.I., Maksioutov M.A., Karpenko S.V., Tumanov K.A., Shchukina N.V., Kochergina E.V.

 

66

Industry Bibliographical Databases: Perspectives of Use in the Fmba of Russia for Scientific Expertise in Decision-Making. Report 2. Database on Health and Other Effects in Uranium Miners

Koterov A.N., Ushenkova L.N., Bulanova T.M., Bogdanenko N.A.

RADIATION DIAGNOSTICS

78

Computed Tomography of Neoplasms of Small Vessels of the Liver in the Differential Diagnosis of Hypervascular Tumors (Clinical Case)

Bashkov A.N., Shabalin M.V., Veselkova A.Yu., Dubova E.A., Matkevich E.I., Dunaev A.P.

 

82

Avascular Necrosis and Bone Marrow Infarction as a Manifestation of Postcovoid Syndrome

Zainagutdinova A.M., Surovtsev E.N., Pyshkina Yu.S., Kapishnikov A.V.

87

Indirect Radionuclide Lymphoscintigraphy in the Assessment of Upper Limb Lymphostasis after Breast Cancer Treatment

Nikolaeva E.A., Krylov A.S., Ryzhkov A.A., Narkevich B.Ya., Filimonov A.V.

RADIATION 
THERAPY

96

Comparative Assessment of Dose Distributions During Proton and Photon Therapy in Patients with Recurrent High-Grade Gliomas

Medvedeva K.E., Adarova A.I., Minaeva N.G., Gulidov I.A., Koryakin S.N.

102

Features of Radiation Reactions in Patients with Prostate Cancer with Metabolic Syndrome on the Background of Thermoradiotherapy

Efanova E.V., Startseva Zh.A., Fursov S.A., Chernyshova A..L,
Tkachuk O.A.

NUCLEAR 
MEDICINE

106

SPECT/CT with 99mTc-PSMA in the Staging and Diagnosis of Hodgkin Lymphoma

Muravleva A.V., Chernov V.I., Goldberg V.E., Shamsimukhametova E.A.,
Zelchan R.V., Medvedeva A.A., Bragina O.D., Popova N.O.,
Vysotskaya V.V., Rybina A.N., Goldberg A.V.