SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 43–47

S.S. Aleksanin, S.V. Serebryakova, I.M. Levashkina

Neocortex (Frontal and Temporal Lobe) Discirculatory Lesions of the Chernobyl Accident Liquidators at the Remote Period (Based on Diffusion Tensor MRI Data)

A.M. Nikiforov Russian Center of Emergency and Radiation Medicine EMERCOM of Russia, S-Petersburg, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To find the distinctive features of the white matter tracts’ structural changes for Chernobyl accident liquidators with ebcephalopathy at the remote period using DT-MRI methods.

Material and methods: Chernobyl accident liquidators group (41 subjects) and group of control (49 subjects), all subjects with stage II of encephalopathy, mean age of liquidators’ group 68.3 ± 6.9 years, gropup of control — 68.6 ± 5.8 years. All subjects were clinically examined to confirm encephalopathy stage, hypertension, diabetes (and prove patients of both groups have comparable level of damage of those deseases), as well as with routine MRI and DT-MRI protocols. According routine MRI results, all subjects of both groups had high level of discirculatory damages: multifocal lesions of white matter and periventricular leukoaraiosis, mixed replacement hydrocephalus.

Results: Liquidator’s group average fraction anisotropy coefficient (CFA) had shown statistically significant reduction in four frontal and temporal lobe tracts of neocortex if compare with average CFA in the group of control: superior longitudinal fasciculi (р < 0.02); front sections of corona radiata (р < 0.02); anterior horn of internal capsule (р < 0.01), inferior longitudinal fasciculi (р < 0.01).

Conclusion: Frontal and temporal lobe tracts of neocortex, responsible for cognitive processes, are the most sensible to accident liquidation negative factors. Cerebral structure changes, found for group of liquidators, are similar to elder people with encephalopathy, but are clnically more strongly marked, what proves hyoptesis of early aging of liquidators’ brain structures.

Key words: nuclear accidents, Chernobyl Nuclear Power Plant, Chernobyl accident liquidator, diffusion-tensor MRI (DT‑MRI), fraction anysotropy (FA), cognitive disorders, discirculatory encephalopathy

For citation: Aleksanin SS, Serebryakova SV, Levashkina IM. Neocortex (Frontal and Temporal Lobe) Discirculatory Lesions of the Chernobyl Accident Liquidators at the Remote Period (Based on Diffusion Tensor MRI Data). Medical Radiology and Radiation Safety. 2020;65(4):43-7 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-43-47

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PDF (RUS) Полная версия статьи

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 15.08.2020. Принята к публикации: 01.09.2020.
Article received: 15.08.2020. Accepted for publication: 01.09.2020.


Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 48–57

T.V. Azizova1, N. Hamada2, E.S. Grigoryeva1, E.V. Bragin1

Risk of Various Types of Cataracts in a Cohort of Mayak Workers Following Chronic Occupational Exposure to Ionizing Radiation

1 Southern Urals Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia
2 Radiation Safety Research Center, Nuclear Technology Research Laboratory,
Central Research Institute of Electric Power Industry, Tokyo, Japan
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To assess cataract type specific risks in a cohort of workers occupationally exposed to ionizing radiation over prolonged periods.

Material and methods: The present retrospective cohort study included 22,377 workers first employed at a nuclear production facility in 1948–1982 and followed up till the end of 2008. By the end of the follow-up period in the study worker cohort 3123 cases of cortical cataract, 1239 cases of posterior subcapsular cataract (PSC) and 2033 cases of nuclear cataracts were registered over 486,245, 489,162, 492,004 person-years of follow-up, respectively.

Results: The incidence of PSC, cortical and nuclear cataracts was significantly linearly associated with the cumulative radiation dose. The excess relative risk per unit dose of external gamma-ray exposure (ERR/Sv) was 0.91 (95 % CI: 0.67–1.20) for PSC, 0.63 (95 % CI: 0.49–0.76) for cortical cataracts and 0.47 (95 % CI: 0.35–0.60) for nuclear cataracts. Exclusion of an adjustment for neutron dose and inclusion of additional adjustments for body mass index and smoking index reduced ERRs/Sv for all types of cataracts. However, an additional adjustment for glaucoma increased the incidence risks of cortical and nuclear cataracts just modestly (but not for PSC). Inclusion of an adjustment for diabetes mellitus reduced the ERR/Sv of external gamma-ray exposure only for PSC incidence. Increased incidence risks of all cataract types were observed in both males and females of the study cohort, but ERR/Sv was significantly higher in females (p < 0.001), especially for PSC.

Conclusion: The incidence of various types of cataracts in the cohort of workers occupationally chronically exposed to ionizing radiation was associated with the cumulative dose of external gamma-ray exposure.

Key words: ionizing radiation, chronic exposure, Mayak PA workers, posterior subcapsular cataract, cortical cataract, nuclear cataract, sex differences

For citation: Azizova TV, Hamada N, Grigoryeva ES, Bragin EV. Risk of Various Types of Cataracts in a Cohort of Mayak Workers Following Chronic Occupational Exposure to Ionizing Radiation. Medical Radiology and Radiation Safety. 2020;65(4):48-57 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-48-57

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  40. Rafnsson V, Olafsdottir E, Hrafnkelsson J, Sasaki H, Amarsson A, Jonasson F. Cosmic radiation increases the risk of nuclear cataract in 3984 airline pilots: A population-based case-control study. Arch Ophthalmol. 2005;123(8):1102-3985. DOI: 10.1001/archopht.123.8.1102.
  41. Hamada N, Sato T. Cataractogenesis following high-LET radiation exposure. Mutat Res. 2016;770(Pt B):262-91. DOI: 10.1016/j.mrrev.2016.08.005.
  42. Azizova TV, Hamada N, Grigoryeva ES, Bragin EV. Risk of various types of cataracts in a cohort of Mayak workers following chronic occupational exposure to ionizing radiation. Eur J Epidemiol. 2018;33(12):1193-204. DOI: 10/1007/s10654-018-0450-4.
  43. Hamada N, Azizova T, Little M. An update on effects of ionizing radiation exposure on the eye. Br J Radiol. 2020;93:20190829. DOI: 10.1259/bjr.20190829.

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Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 29.07.2020. Принята к публикации: 10.09.2020.
Article received: 29.07.2020. Accepted for publication: 10.09.2020.

Information about the autors

Azizova T.V. http://orcid.org/0000-0001-6954-2674
Grigoryeva E.S. http://orcid.org/0000-0003-1806-9922
Bragin E.V. http://orcid.org/0000-0003-0410-5048


Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 65–73

M.V. Osipov1, E.P. Fomin2, M.E. Sokolnikov1

Evaluation of Effects of Diagnostic Exposure Using Data from Epidemiological Registry of Ozyorsk Population Exposed to Computed Tomography

1 Southern Urals Biophysics Institute, Ozyorsk, Russia
2 Clinical Hospital No. 71, Ozyorsk, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To assess the contribution of low doses of diagnostic radiation due to computed tomography to carcinogenic risk among population of Ozersk.

Material and methods: The study describes the results of the analysis of data from the radiation-epidemiological register created in the laboratory of radiation epidemiology of the Southern Urals Biophysics Institute of Ozersk. The register contains information on 26,626 CT examinations of Ozersk residents of all age groups, including children under 1 year old, carried out in medical departments of the Chelyabinsk region during the period from 1993 to 2018.

Results: Based on the analyzed medical and dosimetric information from the CT Register database, the chances of malignant neoplasms among patients exposed to diagnostic irradiation during computed tomography were assessed taking into account the presence of the main radiation and non-radiation factors (age, sex, occupational exposure, number of CT examinations, effective dose and DLP).

Conclusion: In a cohort of Ozersk residents who were exposed to low doses of diagnostic radiation during computed tomography, a statistically significant effect of sex and age attained to malignant neoplasm was obtained. Also, a significant relationship was found between the effective dose from diagnostic CT and the likelihood of subsequent cancer development diagnosed no earlier than 2 years after the first CT examination. At the same time, the DLP did not statistically significantly increase the chances of developing a malignant neoplasm in the study cohort for both the population and the personnel of the Mayak PA.

Key words: medical exposure, computed tomography, diagnostic exposure, occupational exposure, low doses, cancer, radiogenic risk

For citation: Osipov MV, Fomin EP, Sokolnikov ME. Evaluation of Effects of Diagnostic Exposure Using Data from Epidemiological Registry of Ozyorsk Population Exposed to Computed Tomography. Medical Radiology and Radiation Safety. 2020;65(4):65-73 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-65-73

Список литературы / References

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Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 21.08.2020. Принята к публикации: 28.08.2020.
Article received: 21.08.2020. Accepted for publication: 28.08.2020.

Information about the author:
Osipov M.V. http://orcid.org/0000-0002-0732-0379


Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 58–64

S.S. Silkin1, L.Y. Krestinina1, A.V. Akleyev1,2

Solid Cancer Incidence Risk among the Population Exposed
in the East Urals Radioactive Trace over 1957–2014

1 Urals Research Center for Radiation Medicine, Chelyabinsk, Russia
2 Chelyabinsk State University, Chelyabinsk, Russia
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: Assessment of solid cancer incidence risk in the cohort of exposed population on the territory of the East Urals radioactive trace over the period of follow-up from 1957 to 2014 with the use of the individual doses provided by the latest TRDS dosimetry system.

Material and methods: The explosion of the liquid radioactive waste storage tank at the «Mayak» Production Association on 29 September 1957 led to the pollution of the territories of the Chelyabinsk and Sverdlovsk Regions and the formation of the EURT, and the population residing on its territory was subjected to protracted chronic external and internal exposure. The analyzed cohort includes 21,384 people, 2,055 of whom received additional radiation before the 1957 accident due to residing in one of the Techa River settlements. The mean dose to the stomach for the members of the EURT cohort was 36 mGy, the maximum — 1.13 Gy. The analysis was performed using the DATAB and AMFIT programs (statistical software package EPICURE). A simple parametric model of excess relative risk (ERR) was used. Statistical significance and confidence intervals were obtained using the maximum likelihood method.

Results: As a result of the analysis of the solid cancer incidence risk in the EURT cohort during the 57-year follow-up period using the linear model and the 5-year latent period, a statistically significant ERR was obtained which equals to 0.052 / 100 mGy (95 % CI 0.01–0.10, p = 0.02) in the entire EURT cohort. When the group of people additionally exposed on the Techa River before the 1957 accident was excluded from the cohort, the risk became insignificant. No significant modification of the dose dependence by non-radiation factors was revealed. The obtained results are compared well with the previous studies of the exposed population in the Southern Urals which were conducted in the Urals Research Center for Radiation Medicine, as well as in the world, devoted to the study of the effects of radiation exposure on population.

Key words: population, radiation risk, East Urals radioactive trace (EURT), solid cancer, incidence risk, excessive relative risk

For citation: Silkin SS, Krestinina LY, Akleyev AV. Solid Cancer Incidence Risk among the Population Exposed in the East Urals Radioactive Trace over 1957–2014. Medical Radiology and Radiation Safety. 2020;65(4):58-64 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-58-64

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  43. Hamada N, Azizova T, Little M. An update on effects of ionizing radiation exposure on the eye. Br J Radiol. 2020;93:20190829. DOI: 10.1259/bjr.20190829.

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Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 14.08.2020. Принята к публикации: 21.08.2020.
Article received: 14.08.2020. Accepted for publication: 21.08.2020.

Information about the authors:

Silkin S.S. https://orcid.org/0000-0002-4412-4481
Krestinina L.Y. https://orcid.org/0000-0003-0497-5879
Akleyev A.V. https://orcid.org/0000-0003-2583-5808


Medical Radiology and Radiation Safety. 2020. Vol. 65. No. 4. P. 74–86

I.S. Kuznetsova1, M. Gillies2

Radiation Risk of Leukemia Incidence and Mortality in the Pooled Cohort of Nuclear Industry Workers of Russia and Great Britain

1 Southern Urals Biophysics Institute, Ozyorsk, Russia
2 Centre for Radiation Chemical and Environmental Hazards, Public Health England, Oxford, UK
E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: The estimation of the radiation risk of leukemia incidence and mortality for occupational exposure.

Material and methods: The study was conducted in the pooled cohort comprised 45,817 workers from the two enterprises; 23,443 radiation workers first employed in 1947–2002 from the Sellafield plant (Great Britain) and 22,774 workers from the Mayak PA (Russia) first employed at the main plants in 1948–1982. The period of follow-up was terminated at the end of 2008 for Mayak workers who were Ozyorsk city residents, and at the end of 2005 for Sellafield workers and Mayak workers who had migrated from Ozyorsk.

Results: Comparable radiation risk estimates of leukemia incidence and mortality were found among Mayak PA and Sellafield workers as for the whole dose range and separate dose intervals. Averaged by attained age estimate of excess relative risk per 1 Gy of external gamma-dose was 3.0 (95 % CI: 1.3–6.3) under the assumption of the linear dose–effect model. The quadratic model with attained age modification showed the best quality of fit. Risk estimates were statistically significant in the dose range 0.15–1.5 Gy. There was no evidence of any relationship between leukemia risks and accumulated red bone marrow dose of internal alpha-exposure due to incorporated Pu-239.

Conclusion: Preliminary analysis of the pooled cohort data has demonstrated the feasibility and efficiency of a research project looking at leukemia risks in a joint cohort of Mayak and Sellafield workers. The current study provides further evidence about the already well established link between external-gamma exposure and leukemia risk. However, it fails to provide any firm further evidence about the absence or presence of relationship between plutonium exposure and leukemia risk.

Key words: occupational exposure, radiation risk, incidence, mortality, leukemia, Russia, Great Britain, pooled cohort

For citation: Kuznetsova IS, Gillies M. Radiation Risk of Leukemia Incidence and Mortality in the Pooled Cohort of Nuclear Industry Workers of Russia and Great Britain. Medical Radiology and Radiation Safety. 2020;65(4):74-86 (In Russ.).

DOI: 10.12737/1024-6177-2020-65-4-74-86

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PDF (RUS) Полная версия статьи

Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.
Conflict of interest. The authors declare no conflict of interest.
Финансирование. Исследование не имело спонсорской поддержки.
Financing. The study had no sponsorship.
Участие авторов. Cтатья подготовлена с равным участием авторов.
Contribution. Article was prepared with equal participation of the authors.
Поступила: 21.08.2020. Принята к публикации: 27.08.2020.
Article received: 21.08.2020. Accepted for publication: 27.08.2020.

Information about the autor:

Kuznetsova I.S. https://orcid.org/0000-0002-1214-295X


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