JOURNAL DESCRIPTION
The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.
Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.
Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.
The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.
Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.
The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.
Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.
The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.
Issues journals
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 72-82
REVIEW
L.M. Rozhdestvensky
Radiation Countermeasures (Protection and Therapy): Modern Statement, Problems and Prospectives
Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
In Russia radiobiological invesigations there are 2 actual directions of studying pharmacological radiation countermeasures according to real radiation accident scenarios. The first one is effectiveness increasing the severe radiation injury therapy. Another one is searching a radioprotector of prolonged action that would capable to protect against the prolonged radiation exposure of low radiation rate.
On the first direction there is a real possibility to increase effectiveness of the world consensus treatment protocol regarding severe human radiation injuries by means of the home preparation betaleukine usage as a means of the urgent therapy. In experiments on dogs it has been shown that a single s/c betaleukine injection in limits 2 h after lethal radiation exposure is as effective as the G-CSF 3 week course.
At the same time there is a crisis concerning progress in solving such problems as an elaboration of a radioprotector against prolonged low dose rate exposure, a revealing an indicator/ marker of the pharmacologically increased radioresistance (dissolving the problem of the clinical trial 2nd phase realization regarding radioprotectors), the radioprotectors broad usage in a praxis of radiochemotherapy.
Western countries excel now Russia in elaborating new approaches and new preparations in radiation countermeasures, especially in mastering recombinant cytokines and their combinations.
Prospectives in overcoming crisis regarding radiation countermeasures investigations lie in the expansion of genomics and proteomics studies, in knowing intracellular signaling pathways regarding as ionizing radiation as radiation countermeasures action. It is necessary also to modify the radiation countermeasures studying in a way of cell and genomic tests use besides the survival test.
Key words: radiation countermeasures, radioprotectors, antiradiation therapy means, prolonged action radioprotectors, radiation injury scenarios, elevated radioresistance indicators
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 66-71
RADIATION PHYSICS, TECHNOLOGY AND DOSIMETRY
V.V. Kalashnikov, L.A. Naumova, E.V. Rabinkova, O.V. Shishkova
Sterility of Medical Devices after Irradiation and Sterility Test in A.I. Burnazyan FMBC in 2007-2009 years
Burnasyan Federal Medical Biophysical Center of FMBA, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Purpose: To determine the sterility of medical devices that have passed irradiation and sterility test in Burnazyan FMBC.
Material and methods: Measurement presterilization contamination and sterility test sample production batch of products are held in FMBC methods established for the state supervision over the production of radiation-sterilized products, taking into account the species composition of micro flora, which gave rise during incubation, and if there is evidence that sterilization in approved production batch mode.
Results: The direct measurement of acceptance microbiological contamination presterilization, sterilization and sterility test were parts of the production of sterile products. Actually received the product to be sterilized with contamination presterilization 104-105 CFU. It is for these major items is set dose products in the series. The probability of presence of microorganisms capable of division in medical products, which passed in 2007-2009 years of exposure and tests for sterility in FMBC, less than 1x10-6.
Conclusion: The quality of sterilization products irradiated in FMBC beyond the quality of sterilization of products in health care settings. If the mode of sterilization approved, for direct microbiological acceptance of goods of an opportunity to customize the incubation period - seven days and a single medium, provided that it is universal for the cultivation of aerobic and anaerobic bacteria.
Key words: sterilization, medical products, quality of sterilization, test for sterility, presterilization contamination
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 54-57
NUCLEAR MEDICINE
Yu.B. Lishmanov1, N.G. Krivonogov1, T.S. Ageeva2, K.V. Zavadovskiy1, A.V. Dubodelova2
Scintigraphic Peculiariries of Lung Affection in Case of Bronchial Asthma
1. Institute of Cardiology of Tomsk Research Center of the RAMS, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Siberian State Medical University, Tomsk, Russia
Abstract
Purpose: To determine typical scintigraphic signs of ventilationperfusion disorders for bronchial asthma. Material and methods: 20 patients with the verified diagnosis of bronchial asthma at the stage of remission and 10 healthy non-smoking volunteers took part in the study. All the examined subjects underwent ventilation-perfusion lung scintigraphy.
Results: Bronchial asthma patients have positive bilateral increase of the apical-basal gradient of perfusion, reduction of the apical-basal gradient of ventilation and acceleration of alveolar-capillary permeability during the 30th minute of the study as compared to the analogues rates of healthy individuals.
Conclusion: The data received testify to the fact that the scintigraphic assessment of alveolar-capillary permeability of lungs as well as the evaluation of apical-basal gradients of ventilation and perfusion can be used as additional criteria to diagnose bronchial asthma at early stages.
Key words: ventilation-perfusion lung scintigraphy, bronchial asthma, apical-basal gradient of perfusion and ventilation, alveolar-capillary permeability
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 58-65
NUCLEAR MEDICINE
V.D. Zavadovskaya, A.P. Kourazhov, O.Yu. Kilina, I.E. Gerbek, Z.A.Mayevskaya, M.A. Zorkaltsev
199Tl-Chloride-Scintigraphy in Diagnostics of Neoplastic Processes in Lungs and Mediastinum
Siberian State Medical University, Tomsk, Russia, e-mail This email address is being protected from spambots. You need JavaScript enabled to view it. , This email address is being protected from spambots. You need JavaScript enabled to view it.
Abstract
Purpose: Assessment of 199Tl-chloride scintigraphy efficiency in diagnostics of lungs and mediastinum neoplastic processes.
Material and methods: Patients with lungs and mediastinum tumors or inflammations were undergone 199Tl-chloride scintigraphy in early and delayed phases (15 males and 17 females, 33 localizations).
Results: Sensitivity, specificity, positive and negative predictive values and accuracy in the nonspecific indications of the tumor processes were 77.3, 63.6, 81.0, 58.3 and 72.7 %, respectively. Causes of the false negative results were tumors less 2 cm or some histological types of them. Specificity of this method in diagnostics of tumors was increased by the quantitative criteria of RI > –0.199(ER)+1.169. In total, sensitivity, specificity, positive and negative predictive values, and accuracy of the tumor diagnostics in lung and mediastinum were 77.3, 100, 100, 68.8 and 84.8 %, respectively.
Conclusion: 199Tl-chloride scintigraphy may be used successfully for indication of lung and mediastinum tumors of more than 2 cm size. The specificity of 199Tl-chloride scintigraphy was increased by considering the different pharmacokinetics of this marker in the tumor and inflammatory focuses.
Key words: 199Tl-chloride scintigraphy, neoplastic processes, retention index, radionuclide diagnostics, diagnostic efficiency
Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 47-53
RADIATION DIAGNOSTICS
N.A. Chupova1, I.V. Bodrova1, S.К. Ternovoy1, Ya.О. Grusha1,2, S.S. Danilov2
The Role оf Functional Multislice Computed Tomography in Determining the Contractility of the Rectus Muscles in Orbital Trauma
1. I.M. Sechenov First Moscow State Medical University, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. SRI of Eye Diseases of RAMS, Moscow, Russia
Abstract
Purpose: To study the possibilities of a functional multislice computed tomography (fMSCT) in diagnosis of lesion of rectus muscles in orbital trauma in a choice of treatment strategy, planning of tactics and volume of surgical intervention.
Material and methods: This study included 66 patients. From them, women count 40.9 % and men count 59.1 %. The average patient age was 38.6 years. All patients had full ophthalmologic examination, MSCT and fМSCТ of the eyes. Patients were divided into two groups. The first group consisted of 20 patients (volunteers) without the revealed pathological changes at ophthalmologic examination; the 2nd group consisted of 46 patients with the clinical diagnosis - orbital trauma. In three cases, the injury of an orbit was bilateral, in others - unilateral. Surgical treatment was done in 29 orbits that allowed comparing fMSCT data with operative findings.
Results: In the study of 46 patients with orbital trauma according to MSCT, the topography of orbital deformations was detailed. From the second group, 17 (38 %) patients had lesion of the inferior wall of an orbit, 20 (44 %) - of medial wall, nine (20 %) - of lateral wall, nine (20 %) - of superior wall; 25 (56 %) patients had lesion of two or more walls; three (6.7 %) patients did not have any changes of the orbital walls. According by fMSCT data, the diligence of a muscle to a fracture area of a bone wall without violation of contractile ability was found in six cases. In 10 cases, the fixation of a muscle to a fracture area with strands (‘commissure’) with preservation of contractile ability was noted. In eight of these cases, the restriction of motility of an eyeball was caused by existence of these strands. In three cases, the strangulation of rectus muscle in a fracture area and decrease of contractile ability was found. In three cases, the paralysis of a lateral rectus muscle was revealed. Also at fMSCT, the reduction of cross-section of a rectus muscle with decrease of contractile ability was found in three cases; in one case, the rupture of an lateral rectus muscle without violation of contractile ability was revealed; in one case, the displacement and a pressing of a rectus muscle by a bone implant with preservation of its contractile ability was revealed. In 10 cases, fractures of the walls without changes of the muscular system were only found.
Conclusion: The obtained results allowed to develop the protocol of fMSCT, to study normal functional anatomy of the eye, and to estimate normal contractile ability of rectus muscles. The research showed the necessity of using the fMSCT of the eye with orbital trauma in assessment of contractile ability of rectus muscles and their involvement in relation to the field of fracture. The improvement of diagnosis obtained by fMSCT has allowed to choose an optimal tactics and scope of surgical intervention.
Key words: multislice computed tomography (MSCT), functional multislice computed tomography (fMSCT), orbit, rectus muscles, orbital trauma