SCIENTIFIC AND INFORMATION-ANALYTICAL MAGAZINE

ISSN 1024-6177 (Print), ISSN 2618-9615 (Online)

JOURNAL DESCRIPTION

The Medical Radiology and Radiation Safety journal ISSN 1024-6177 was founded in January 1956 (before December 30, 1993 it was entitled Medical Radiology, ISSN 0025-8334). In 2018, the journal received Online ISSN: 2618-9615 and was registered as an electronic online publication in Roskomnadzor on March 29, 2018. It publishes original research articles which cover questions of radiobiology, radiation medicine, radiation safety, radiation therapy, nuclear medicine and scientific reviews. In general the journal has more than 30 headings and it is of interest for specialists working in thefields of medicine¸ radiation biology, epidemiology, medical physics and technology. Since July 01, 2008 the journal has been published by State Research Center - Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency. The founder from 1956 to the present time is the Ministry of Health of the Russian Federation, and from 2008 to the present time is the Federal Medical Biological Agency.

Members of the editorial board are scientists specializing in the field of radiation biology and medicine, radiation protection, radiation epidemiology, radiation oncology, radiation diagnostics and therapy, nuclear medicine and medical physics. The editorial board consists of academicians (members of the Russian Academy of Science (RAS)), the full member of Academy of Medical Sciences of the Republic of Armenia, corresponding members of the RAS, Doctors of Medicine, professor, candidates and doctors of biological, physical mathematics and engineering sciences. The editorial board is constantly replenished by experts who work in the CIS and foreign countries.

Six issues of the journal are published per year, the volume is 13.5 conventional printed sheets, 88 printer’s sheets, 1.000 copies. The journal has an identical full-text electronic version, which, simultaneously with the printed version and color drawings, is posted on the sites of the Scientific Electronic Library (SEL) and the journal's website. The journal is distributed through the Rospechat Agency under the contract № 7407 of June 16, 2006, through individual buyers and commercial structures. The publication of articles is free.

The journal is included in the List of Russian Reviewed Scientific Journals of the Higher Attestation Commission. Since 2008 the journal has been available on the Internet and indexed in the RISC database which is placed on Web of Science. Since February 2nd, 2018, the journal "Medical Radiology and Radiation Safety" has been indexed in the SCOPUS abstract and citation database.

Brief electronic versions of the Journal have been publicly available since 2005 on the website of the Medical Radiology and Radiation Safety Journal: http://www.medradiol.ru. Since 2011, all issues of the journal as a whole are publicly available, and since 2016 - full-text versions of scientific articles. Since 2005, subscribers can purchase full versions of other articles of any issue only through the National Electronic Library. The editor of the Medical Radiology and Radiation Safety Journal in accordance with the National Electronic Library agreement has been providing the Library with all its production since 2005 until now.

The main working language of the journal is Russian, an additional language is English, which is used to write titles of articles, information about authors, annotations, key words, a list of literature.

Since 2017 the journal Medical Radiology and Radiation Safety has switched to digital identification of publications, assigning to each article the identifier of the digital object (DOI), which greatly accelerated the search for the location of the article on the Internet. In future it is planned to publish the English-language version of the journal Medical Radiology and Radiation Safety for its development. In order to obtain information about the publication activity of the journal in March 2015, a counter of readers' references to the materials posted on the site from 2005 to the present which is placed on the journal's website. During 2015 - 2016 years on average there were no more than 100-170 handlings per day. Publication of a number of articles, as well as electronic versions of profile monographs and collections in the public domain, dramatically increased the number of handlings to the journal's website to 500 - 800 per day, and the total number of visits to the site at the end of 2017 was more than 230.000.

The two-year impact factor of RISC, according to data for 2017, was 0.439, taking into account citation from all sources - 0.570, and the five-year impact factor of RISC - 0.352.

Issues journals

Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 47-53

RADIATION DIAGNOSTICS

N.A. Chupova1, I.V. Bodrova1, S.К. Ternovoy1, Ya.О. Grusha1,2, S.S. Danilov2

The Role оf Functional Multislice Computed Tomography in Determining the Contractility of the Rectus Muscles in Orbital Trauma

1. I.M. Sechenov First Moscow State Medical University, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. SRI of Eye Diseases of RAMS, Moscow, Russia

Abstract

Purpose: To study the possibilities of a functional multislice computed tomography (fMSCT) in diagnosis of lesion of rectus muscles in orbital trauma in a choice of treatment strategy, planning of tactics and volume of surgical intervention.

Material and methods: This study included 66 patients. From them, women count 40.9 % and men count 59.1 %. The average patient age was 38.6 years. All patients had full ophthalmologic examination, MSCT and fМSCТ of the eyes. Patients were divided into two groups. The first group consisted of 20 patients (volunteers) without the revealed pathological changes at ophthalmologic examination; the 2nd group consisted of 46 patients with the clinical diagnosis - orbital trauma. In three cases, the injury of an orbit was bilateral, in others - unilateral. Surgical treatment was done in 29 orbits that allowed comparing fMSCT data with operative findings.

Results: In the study of 46 patients with orbital trauma according to MSCT, the topography of orbital deformations was detailed. From the second group, 17 (38 %) patients had lesion of the inferior wall of an orbit, 20 (44 %) - of medial wall, nine (20 %) - of lateral wall, nine (20 %) - of superior wall; 25 (56 %) patients had lesion of two or more walls; three (6.7 %) patients did not have any changes of the orbital walls. According by fMSCT data, the diligence of a muscle to a fracture area of a bone wall without violation of contractile ability was found in six cases. In 10 cases, the fixation of a muscle to a fracture area with strands (‘commissure’) with preservation of contractile ability was noted. In eight of these cases, the restriction of motility of an eyeball was caused by existence of these strands. In three cases, the strangulation of rectus muscle in a fracture area and decrease of contractile ability was found. In three cases, the paralysis of a lateral rectus muscle was revealed. Also at fMSCT, the reduction of cross-section of a rectus muscle with decrease of contractile ability was found in three cases; in one case, the rupture of an lateral rectus muscle without violation of contractile ability was revealed; in one case, the displacement and a pressing of a rectus muscle by a bone implant with preservation of its contractile ability was revealed. In 10 cases, fractures of the walls without changes of the muscular system were only found.

Conclusion: The obtained results allowed to develop the protocol of fMSCT, to study normal functional anatomy of the eye, and to estimate normal contractile ability of rectus muscles. The research showed the necessity of using the fMSCT of the eye with orbital trauma in assessment of contractile ability of rectus muscles and their involvement in relation to the field of fracture. The improvement of diagnosis obtained by fMSCT has allowed to choose an optimal tactics and scope of surgical intervention.

Key words: multislice computed tomography (MSCT), functional multislice computed tomography (fMSCT), orbit, rectus muscles, orbital trauma

 Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 42-46

RADIATION THERAPY

K.G. Moskalik, A.P. Kozlov

Clinical and Morphological Factors in Evaluation of Efficacy of Facial Carcinoma Treatment by High-energy Pulsed Neodymium Laser

N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: This trial has estimated an influence of clinicalmorphological factors of facial carcinomas on the results of its treatment by means of Neodymium laser radiation.

Material and methods: The radiation of high-energy mono-pulsed laser (λ = 1060 nm) was used for treatment of 2,805 patients with 2,940 morphologically confirmed facial carcinoma of stages T1–2N0M0. Out of them, there were 2,845 primary basal cell carcinoma (BCC) and 95 squamous cells carcinoma (SCC). The patients were followed-up from 1 to 13 years.

Results: Overall, the recurrence rate after laser radiation was 2.0 % of all irradiated tumours. The highest rate of recurrences was found in SCC (5.3 %) if compared to BCC (1.9 %). Also high rate of recurrences was detected in infiltrative-ulcerative (4.5 %) tumours as well as in lesions located in nasolabial area (3.2 %). Rate of recurrences has increased along with the enlarging stage of disease.

Conclusion: Neodymium laser radiation is a practical and useful method for treatment of facial carcinomas, which results depend on tumour morphology, their clinical characteristic, localization and stage of disease.

Key words: facial carcinoma, neodymium laser, non-ionization radiation

Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 31-36

RADIATION MEDICINE

I.A. Galstyan, N.M. Nadejina

Local Radiation Injuries as Complications of Medical Radiation Exposure

Burnazyan Federal Medical Biophysic Center of Federal Medical Biology Agency of Russia, Moscow, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To familiarize medical doctors with situations of diagnostic and therapeutic medical radiation exposure where the development of acute radiation injuries in patients is possible. The clinical cases are addressed to medical doctors to whom patients with complaints in connection with developing local radiation injuries (LRI) can apply.

Material and methods: The analysis of archival materials of 214 patients with the LRI which were under dynamic supervision of clinic of Burnazyan FMBC has allowed to reveal 15 patients injured with medical radiation.

Results: Descriptions of case histories for 13 out of 15 patients exposed to medical radiation concerning various neoplasms and nononcological diseases and at which LRI of the II-IV degree were developed.

Conclusions: 1. Carrying out radiation diagnostic and therapeutic procedures occasionally can become complicated by LRI development.

  1. The reasons of development of radiation injuries can be: technical malfunction of the equipment, safety measures violation by personnel carrying out procedures, the specific features of the patient changing routine characteristics of exposure; the severe somatic status of the patient is the reason of more severe trophopathy of irradiated tissues.
  2. In cardiological practice of the diagnostic and medical procedures which are carried out under an X-ray control, approximately 3 % of cases led to development of acute LRI. Repeated interventions possibly develop of signs of chronic radiation dermatitis.

Key words: local radiation injuries, complications of medical radiation exposure, radiation therapy, X-rays -examination

REFERENCES

  1. Chida K., Saito H., Otani H. et al. Relationship between fluoroscopic time, dose-area product, body weight, and maximum radiation skin dose in cardiac interventional procedures. Amer. J. Roentgenol. 2006. Vol. 186. No. 3. P. 774-778.
  2. Slovut D. Cutaneous radiation injury after complex coronary intervention. JACC Cardiovasc. Interv. 2009. Vol. 2. No. 7. P. 701-702.
  3. Mettler F.A., Jr., Ortiz-Lopez P. Accidents in radiation therapy. In “Medical Management of Radiation Accidents”. Ed. by I.A. Gusev, A.K. Guskova, F.A. Mettler. CRC Press. 2001. P. 291-297.
  4. Sharp Ch. Medical accidents with local injury from use of medical fluoroscopy. In “Medical Management of Radiation Accidents”. Ed. by I.A. Gusev, A.K. Guskova, F.A. Mettler. CRC Press. 2001. P. 313-318.
  5. Tanaka J. The potential patient skin injuries from radiologically guided interventional procedure: the present condition and recommendable measure. Igaku Butsuri. 2002. Vol. 22. No. 2. P. 98-104.
  6. Kato M., Chida R., Sato T. et al. Patient skin injury in cardiac intervention procedures. Nihon Hoshasen Gijutsu Gakkai Zasshi. 2010. Vol. 66. No. 6. P. 688-689.
  7. Aerts A., Decraene T., van den Oord J.J. et al. Chronic radiodermatitis following percutaneous coronary interventions: a report of two cases. J. Eur. Acad. Dermatol. Venereol. 2003. Vol. 17. No. 3. P. 340-343.
  8. Banaag L.O., Carter M.J. Radionecrosis induced by cardiac imaging procedures: a case study of a 66-yearold diabetic male with comorbidities. J. Invasive Cardiol. 2008. Vol. 20. No. 8. P. 233-236.
  9. Valentin J. Avoidance of Radiation Injuries from Medical Interventional procedures. Ann. ICRP. 2000. Vol. 30. No. 2. P. 7-67.
  10. Vlietstra R.E., Wagner L.K., Koenig T., Mettler F. Radiation burns as a severe complication of fluoroscopically guided cardiological interventions. J. Interv. Cardiol. 2004. Vol. 17. No. 3. P. 131-142.
  11. Wong L., Rehm J. Radiation injury from a fluoroscopic procedure. N. Engl. J. Med. 2004. Vol. 350. No. 25. P. 23-32.
  12. Bogaert E., Bacher K., Lemmens K. et al. A large-scale multicentre study of patient skin doses in interventional cardiology: dose-area product action levels and dose reference levels. Brit. J. Radiol. 2009. Vol. 82. No. 976. P. 303-312.
  13. Mettler F.A. Jr., Koenig T.R., Wagner L.K., Kelsey C.A. Radiation injuries after fluoroscopic procedures. Semin. Ultrasound. CT. MR. 2002. Vol. 23. No. 5. P. 428-442.
  14. Granel F., Barbaud A., Gillet-Terver M.N. et al. Chronic radiodermatitis after interventional cardiac catheterization. Four cases. Ann. Dermatol. Venerol. 1998. Vol. 125. No. 6-7. P. 405-407.
  15. Vano E., Goicolea J., Galvan C. et al. Skin radiation injuries in patients following repeated coronary angioplasty procedures. Brit. J. Radiol. 2001. Vol. 74. No. 887. P. 1023-1031.
  16. Kawakami T., Saito R., Miyazaki S. Chronic radiodermatitis following repeated percutaneous transluminal coronary angioplasty. Brit. J. Dermatol. 1999. Vol. 141. No. 1. P. 150-153.
  17. Sovik E., Klow N.E., Hellesnes J., Lykke J. Radiationinduced skin injuey after percutaneous transluminal coronary angioplasty. Case report. Acta Radiol. 1996. Vol. 37. No. 1. Pt. 1. P. 305-306.
  18. Monaco J.L., Bowen K., Tadros P.N., Witt P.D. Iatrogenic deep muscolocutaneous radiation injury following percutaneous coronary intervention. J. Invasive Cardiol. 2003. Vol. 15. No. 8. P. 451-453.
  19. Kotenko K.V., Eremin I.I., Moroz B.B. et. al.  Kletochnye tekhnologii v lechenii radiatsionnykh ozhogov: opyt FMBTs im. A.I. Burnazyana. Kletochnaya transplantologiya i tkanevaya inzheneriya. 2012, Vol. VII. No. 2. P. 97-102.

Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 37-41

RADIATION THERAPY

N.V. Ilyin, Yu.N. Vinogradova, A.I. Karyagina, A.I. Urbansky, E.V. Trishkina

Electron-Photon Therapy in Malignant Solid Tumors Treatment with Lesions of the Eye

Russian Research Centre for Radiology and Surgical Technologies, Saint-Petersburg, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Abstract

Purpose: To increase the radiation therapy efficacy in ophthalmooncological patients.

Material and methods: Investigation includes 36 patients with verified malignant solid tumors with lesions of the organ of sight - 32 patients with recurrence after operative treatment and 4 patients with metastases in the orbit. In 16 patients, besides the lesion of eyelids and orbit, an involvement of the maxillary sinus, ethmoidal labyrinth, frontal sinus, skin and soft tissues of face was revealed. All patients received electron-photon therapy (EFT) within period of 1994-2011, including irradiation of the structures of the organ of sight, and in 16 patients, in addition, neighboring injured areas. EFT was carried out at electron linear accelerators SL 75-5 (Philips) of 6 MeV and Elekta Precise by bremsstrahlung radiation of 6 and 18 MV or electrons of 4-18 MeV in 3 regimen of fractionation – conventional (CF, 18 patients), average (AF, 9 patients) and multi-fractionation (MF, 9 patients) to total focal equivalent doses of 55-70 Gy.

Results: After EFT, an objective response was recorded in 29 patients out of 36 (80.6 %), in 12 (33.3 %) out of them - complete response; stabilization was observed in 11 (19.5 %) patients without any

progression at the background of the treatment. In case of the irradiation of eyelids or eyelids and neighbouring structures, the complete or partial remission was noted in all patients; in EFT of the orbit or orbit and neighbouring structures, the response was recorded in 73.9 % of patients (p < 0.01). Irradiation of patients in regimen AF and MF was more effective in comparison with CF - 94.4 % and 66.7 % remissions, correspondingly, p < 0.01; and only in locally spread tumors, the response to the treatment was observed in all patients received EFT in regimen AF and MF. EFT enables to reveal early radiation reactions of stages I-II in 83.7 % of patients; there were not severe complications; reactions rate was higher in CF (94.4 % of patients) and in total in CF and AF (92.6 % of patients) than that in patients irradiated twice a day - 66.7 % of patients, p < 0.05. Onset time of radiation reactions appearance did not depend on fractionation regimen. After EFT, overall 3-5-year survival was 85.9 % and 70.4 %, respectively.

Conclusion: EFT is the important and effective method of treatment in patients with malignant solid tumors with lesions of the organ of sight.

Key words: radiotherapy, organ of sight, solid tumors

Medical Radiology and Radiation Safety. 2012. Vol. 57. No. 5. P. 20-30

RADIATION SAFETY

V.F. Demin1, V.V. Romanov2, V.Yu. Soloviev3

Harmonized Approach to the Health Safety Regulation in Different Areas of Human Activity

1. National Research Center “Kurchatov Institute”, Moscow, Russia, e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. ; 2. Federal Medical Biological Agency, Moscow, Russia; 3. Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency, Moscow, Russia

Abstract

Purpose: To create harmonization approach to the development of health safety standards (HSS) in nanotechnology and other areas of human activity.

Material and methods: Main principles of health risk assessment are: principles of justification and optimization of protection; risk level limit application.

Results: Two types of harmonization are suggested: at the first stage it is necessary to overcome existing divergences and prepare scientific basis of harmonization of hygienic regulations in different areas of human activity. It makes possible to prepare basis for international harmonization of health safety standards (HSS) and other hygienic regulations.

General approach to establishing HSSs and other levels of health risk assessment using risk analysis in different areas of human activity is suggested. On the basis of this approach, universal HSSs for workers and public are suggested. Based on these universal HSSs, general HSSs and other levels of health risk assessment for different modern harm sources are proposed.

Conclusion: The approach can be the basis for harmonization of international regulations and methodological documents in the area of innovative projects’ protection in different areas of industrial and economic human activities.

Key words: risk assessment, risk index, methodology, health risk standard, harmonization, decision making principle

  1. 2012-5-Kiselev-eng
  2. 2012-5-Kotenko-eng
  3. 2012-6-Guskova-eng
  4. 2012-6-Sharypova-eng

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